@article{ART001316165},
author={김형준 and 홍서영 and 허동석 and 윤일지 and Minseok Oh},
title={The Inhibitory Effects of Sansayukbokhap-bang(SSYBHB) on the Obese-Mouse Induced High Fat Diet},
journal={Journal of Korean Medicine for Obesity Research},
issn={1976-9334},
year={2008},
volume={8},
number={1},
pages={33-49}
TY - JOUR
AU - 김형준
AU - 홍서영
AU - 허동석
AU - 윤일지
AU - Minseok Oh
TI - The Inhibitory Effects of Sansayukbokhap-bang(SSYBHB) on the Obese-Mouse Induced High Fat Diet
JO - Journal of Korean Medicine for Obesity Research
PY - 2008
VL - 8
IS - 1
PB - The Society of Korean Medicine for Obesity Research
SP - 33
EP - 49
SN - 1976-9334
AB - Objectives
In order to investigate the effects of Sansayukbokhap-bang (SSYBHB) on the hematological and histological changes.
Methods
C57BL/6 mice were fed with high fat diet. C57BL/6 mice were divided into four groups and fed for 15weeks.
Results
1. The body weight of SSYBHB intake mice was significantly lower than high fat diet group.
2. The final increase of body weight was decreased significantly.
3. The levels of ALT, AST, total cholesterol, LDL-Cholesterol, triglyceride, Leptin were decreased significantly.
4. The levels of creatinine were decreased but did not show significance.
5. The level of HDL-cholesterol and the expression of β3AR mRNA gene in 3T3-L1 Adipocytes were increased significantly.
6. Adipocytes' size was decreased significantly.
7. The expression of β3AR mRNA gene, Leptin mRNA gene and serotinin mRNA gene in Adipocytes tissue was decreased significantly.
Conclusion
Based on these results, it is proved that SSYBHB is effective on the therapy of obesity by referring to obese-gene and obese inhibitory. So,
it is espected that the clinical application of SSYBHB can help the treatment of obesity.
KW - Sansayukbokhap-bang;obesity;C57BL/6mice;body weight
DO -
UR -
ER -
김형준, 홍서영, 허동석, 윤일지 and Minseok Oh. (2008). The Inhibitory Effects of Sansayukbokhap-bang(SSYBHB) on the Obese-Mouse Induced High Fat Diet. Journal of Korean Medicine for Obesity Research, 8(1), 33-49.
김형준, 홍서영, 허동석, 윤일지 and Minseok Oh. 2008, "The Inhibitory Effects of Sansayukbokhap-bang(SSYBHB) on the Obese-Mouse Induced High Fat Diet", Journal of Korean Medicine for Obesity Research, vol.8, no.1 pp.33-49.
김형준, 홍서영, 허동석, 윤일지, Minseok Oh "The Inhibitory Effects of Sansayukbokhap-bang(SSYBHB) on the Obese-Mouse Induced High Fat Diet" Journal of Korean Medicine for Obesity Research 8.1 pp.33-49 (2008) : 33.
김형준, 홍서영, 허동석, 윤일지, Minseok Oh. The Inhibitory Effects of Sansayukbokhap-bang(SSYBHB) on the Obese-Mouse Induced High Fat Diet. 2008; 8(1), 33-49.
김형준, 홍서영, 허동석, 윤일지 and Minseok Oh. "The Inhibitory Effects of Sansayukbokhap-bang(SSYBHB) on the Obese-Mouse Induced High Fat Diet" Journal of Korean Medicine for Obesity Research 8, no.1 (2008) : 33-49.
김형준; 홍서영; 허동석; 윤일지; Minseok Oh. The Inhibitory Effects of Sansayukbokhap-bang(SSYBHB) on the Obese-Mouse Induced High Fat Diet. Journal of Korean Medicine for Obesity Research, 8(1), 33-49.
김형준; 홍서영; 허동석; 윤일지; Minseok Oh. The Inhibitory Effects of Sansayukbokhap-bang(SSYBHB) on the Obese-Mouse Induced High Fat Diet. Journal of Korean Medicine for Obesity Research. 2008; 8(1) 33-49.
김형준, 홍서영, 허동석, 윤일지, Minseok Oh. The Inhibitory Effects of Sansayukbokhap-bang(SSYBHB) on the Obese-Mouse Induced High Fat Diet. 2008; 8(1), 33-49.
김형준, 홍서영, 허동석, 윤일지 and Minseok Oh. "The Inhibitory Effects of Sansayukbokhap-bang(SSYBHB) on the Obese-Mouse Induced High Fat Diet" Journal of Korean Medicine for Obesity Research 8, no.1 (2008) : 33-49.