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The Comparisons of Eating-Related Index and Pre- and Post-Prandial Gut Hormone Patterns between Normal-Overweight and Obese Subjects of Taeemin

  • Journal of Korean Medicine for Obesity Research
  • Abbr : J Korean Med Obes Res
  • 2014, 14(1), pp.36-45
  • DOI : 10.15429/jkomor.2014.14.1.36
  • Publisher : The Society of Korean Medicine for Obesity Research
  • Research Area : Medicine and Pharmacy > Korean Medicine
  • Published : June 30, 2014

이지원 1 박병주 1 Jun-Hee Lee 1

1경희대학교

Candidate

ABSTRACT

Objectives: The purpose of this studay was to compare the eating-related index and the patternsof pre- and post-prandial gut hormone level in normal-overweight and obese subjects of Taeeminpopulation. Methods: We enrolled healthy male participants who were diagnosed with Taeeumin by SasangConstitutional diagnosis and who were normal-overweight (18.5 kg/m2≤body mass index[BMI)< 25 kg/m2) or obese (25.0 kg/m2≤BMI<30 kg/m2). Eating behavior and gastrointestinalproblems were assessed by using standardized scale. Subjective appetite ratings using visualanalogue scales and the profiling of serum levels of ghrelin and peptide YY (PYY) were assessedbefore and after a standard meal (6 time points: 30 minutes pre-prandial, immediately beforemeal, 15, 30, 60, and 120 minutes post-prandial). Results: Tewnty two healthy Taeeumin people classified as normal-overweight group or obesegroup are the final subjects. External eating score of Dutch eating behavior questionaire scoresis higher in normal-overweight group than in obese group. The variations of subjective appetiteratings in obese group are smaller than in normal-overweight group. The pattern of ghrelin innormal-overweight group shows a high peak at 30 minutes post-prandial point, which is contraryto existing studies. The pattern of PYY in obese group decreases from 15 minutes post-prandialpoint and shows lower peak level, whereas in normal-overweight group shows increasingtendency from pre-prandial point until 30 minutes post-prandial point. Conclusions: There are differences in the eating-related index and the gut hormone patternsrelated to obesity.

Citation status

* References for papers published after 2023 are currently being built.

This paper was written with support from the National Research Foundation of Korea.