본문 바로가기
  • Home

Effect of Atractylodes Rhizoma Alba, Houttuyniae Herba, Lonicerae Flos, Agrobacterium Rhizogenes and Coptidis Rhizoma Extracts Combined with Metformin on the Antioxidant and Adipocyte Differentiate Inhibition

  • Journal of Korean Medicine for Obesity Research
  • Abbr : J Korean Med Obes Res
  • 2015, 15(1), pp.24-32
  • Publisher : The Society of Korean Medicine for Obesity Research
  • Research Area : Medicine and Pharmacy > Korean Medicine
  • Published : June 30, 2015

장세주 1 한경선 1 Jing-Hua Wang 1 채희성 2 Choi, Young-Hee 1 CHIN, YOUNG-WON 1 Choi, Han-Seok ORD ID 1 Hojun Kim 1

1동국대학교
2동국대학교 약학대학 약학교실

Candidate

ABSTRACT

Objectives: This study was to investigate the antioxiative capacity, antiobesity effects of Atractylodes Rhizoma Alba, Houttuyniae Herba, Lonicerae Flos, Agrobacterium Rhizogenes, and Coptidis Rhizoma on Raw 264.7 and 3T3-L1 cell lines.Methods: Three different types of herb extracts (A. Rhizoma Alba, H. Herba, L. Flos, A. Rhizogenes, and C. Rhizoma; water 100%, ethanol 30%, ethanol 100%) were used in this study. Total polyphenol compound, 1-diphenyl-2-picrylhydrazyl (DPPH) radical scavenging, reactive oxygen species (ROS) activity, NO production and cell proliferation were measured.Results: Total polyphenol compound measurement of L. Flos, A. Rhizogenes, and C. Rhizoma extracts were higher than A. Rhizoma Alba, H. Herba. DPPH radical scavenging activity, ROS activity and NO production of A. Rhizogenes, C. Rhizoma extracts were lower than L. Flos, A. Rhizoma, and H. Herba.Conclusions: Metformin and A. Rhizogenes, C. Rhizoma, A. Rhizoma Alba, and L. Flos extracts combination groups showed synergistic effect on adipocyte differentiation inhibition and antioxidative activity.

Citation status

* References for papers published after 2022 are currently being built.