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A Complex Region Analysis Algorithm of Two Dimensional Electrophoresis Images Using Accumulated Gradients

  • Journal of The Korea Society of Computer and Information
  • Abbr : JKSCI
  • 2009, 14(7), pp.41-48
  • Publisher : The Korean Society Of Computer And Information
  • Research Area : Engineering > Computer Science

김미애 1 YOON YOUNG WOO 2

1경북전략산업기획단
2영남대학교

Accredited

ABSTRACT

A solution to the problems of recognizing as one spot or detection failures for complex regions, in which many spots representing proteins are overlapped and saturated, is suggested. The accumulated gradients of each point in complex regions are calculated, and the resulting accumulated gradient image segmented using watershed technique. The suggested solution show better and efficient result than existing method for spot separation, detects more protein spots hidden in the image of 2-dimensional electrophoresis, and expands the scope of prediction.

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