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@article{ART002129603},
author={Kwang-Soon Kang},
title={Effects of Purslane Extract on Obesity and Diabetes in High-Fat Diet-Induced Obese Mice},
journal={Journal of The Korea Society of Computer and Information},
issn={1598-849X},
year={2016},
volume={21},
number={7},
pages={61-66}

TY - JOUR
AU - Kwang-Soon Kang
TI - Effects of Purslane Extract on Obesity and Diabetes in High-Fat Diet-Induced Obese Mice
JO - Journal of The Korea Society of Computer and Information
PY - 2016
VL - 21
IS - 7
PB - The Korean Society Of Computer And Information
SP - 61
EP - 66
SN - 1598-849X
AB - The frequency of obesity has risen dramatically in recent years but only few safe and effective drugs are currently available. In addition, obesity can induce type 2 diabetes (T2DM), hyperlipidemia and fatty liver disease. Recently, protective effect of purslane extract (PE) on obesity has been reported, but little is known about the role and mechanism of PE in obesity. This study aimed to evaluate the effect of PE on obesity and diabetes in obese mice. In addition, the effect of PE was compared with anti-obesity and diabetes drugs. High-fat diet (HFD)-induced obese mice were treated for 8 weeks with drugs as follows: PE, orlistat, metformin, voglibose or pioglitazone. While PE mixed with normal diet did not have any effects on BW in non-obese mice, PE mixed with HFD significantly reduced BW gain, insulin resistance, and glucose intolerance, without affecting food intake and appetite in obese mice. The effect was comparable to the effects of anti-obesity and diabetes drugs. Furthermore, PE significantly increased the activity of hepatocellular anti-oxidant enzymes, leading to protection of liver from oxidative stress in obese mice. These results suggest that PE treatment may be a useful tool for preventing obesity and complication of obesity.
KW - Purslane;Obesity;Type 2 diabetes;glucose tolerance;fatty liver
DO -
UR -
ER -

Kwang-Soon Kang. (2016). Effects of Purslane Extract on Obesity and Diabetes in High-Fat Diet-Induced Obese Mice. Journal of The Korea Society of Computer and Information, 21(7), 61-66.

Kwang-Soon Kang. 2016, "Effects of Purslane Extract on Obesity and Diabetes in High-Fat Diet-Induced Obese Mice", Journal of The Korea Society of Computer and Information, vol.21, no.7 pp.61-66.

Kwang-Soon Kang "Effects of Purslane Extract on Obesity and Diabetes in High-Fat Diet-Induced Obese Mice" Journal of The Korea Society of Computer and Information 21.7 pp.61-66 (2016) : 61.

Kwang-Soon Kang. Effects of Purslane Extract on Obesity and Diabetes in High-Fat Diet-Induced Obese Mice. 2016; 21(7), 61-66.

Kwang-Soon Kang. "Effects of Purslane Extract on Obesity and Diabetes in High-Fat Diet-Induced Obese Mice" Journal of The Korea Society of Computer and Information 21, no.7 (2016) : 61-66.

Kwang-Soon Kang. Effects of Purslane Extract on Obesity and Diabetes in High-Fat Diet-Induced Obese Mice. Journal of The Korea Society of Computer and Information, 21(7), 61-66.

Kwang-Soon Kang. Effects of Purslane Extract on Obesity and Diabetes in High-Fat Diet-Induced Obese Mice. Journal of The Korea Society of Computer and Information. 2016; 21(7) 61-66.

Kwang-Soon Kang. Effects of Purslane Extract on Obesity and Diabetes in High-Fat Diet-Induced Obese Mice. 2016; 21(7), 61-66.

Kwang-Soon Kang. "Effects of Purslane Extract on Obesity and Diabetes in High-Fat Diet-Induced Obese Mice" Journal of The Korea Society of Computer and Information 21, no.7 (2016) : 61-66.