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@article{ART002807749},
author={Kim Mee Kyung},
title={Anti-inflammatory Effect of Broccoli Leaf Hexane Fraction in LPS-stimulated RAW264.7 Cells},
journal={Journal of The Korea Society of Computer and Information},
issn={1598-849X},
year={2022},
volume={27},
number={1},
pages={175-181},
doi={10.9708/jksci.2022.27.01.175}

TY - JOUR
AU - Kim Mee Kyung
TI - Anti-inflammatory Effect of Broccoli Leaf Hexane Fraction in LPS-stimulated RAW264.7 Cells
JO - Journal of The Korea Society of Computer and Information
PY - 2022
VL - 27
IS - 1
PB - The Korean Society Of Computer And Information
SP - 175
EP - 181
SN - 1598-849X
AB - In this study, we tested the anti-inflammatory effects of broccoli leaf hexane fraction to confirm the applicability as a functional material in food and cosmetics. This sample was extracted using 70% ethanol from Broccoli leaf and then fractionated with hexane. The production of pro-inflammatory cytokines (TNF-α, IL-4, IL-6, IL-1β), protein expression of iNOS and COX-2, phosphorylation of MAPKs (ERK, JNK, p38) and NF-κB with broccoli leaf hexane fraction were assayed on LPS-stimulated RAW264.7 cells. The broccoli leaf hexane fraction inhibited the secretion of pro-inflammatory cytokines and protein expression of iNOS and COX-2. Also, the broccoli leaf hexane fraction reduced the phosphorylation of MAPKs and NF-κB. Therefore, it is considered that th broccoli leaf hexane fraction has the potential to be used as a natural anti-inflammatory material in food and cosmetics. In the future, it is considered necessary to study the anti-inflammatory mechanism and identification of major bioactive substances.
KW - Anti-inflammatory effect;Broccoli leaf;iNOS & COX-2;MAPKs;NF-κB
DO - 10.9708/jksci.2022.27.01.175
ER -

Kim Mee Kyung. (2022). Anti-inflammatory Effect of Broccoli Leaf Hexane Fraction in LPS-stimulated RAW264.7 Cells. Journal of The Korea Society of Computer and Information, 27(1), 175-181.

Kim Mee Kyung. 2022, "Anti-inflammatory Effect of Broccoli Leaf Hexane Fraction in LPS-stimulated RAW264.7 Cells", Journal of The Korea Society of Computer and Information, vol.27, no.1 pp.175-181. Available from: doi:10.9708/jksci.2022.27.01.175

Kim Mee Kyung "Anti-inflammatory Effect of Broccoli Leaf Hexane Fraction in LPS-stimulated RAW264.7 Cells" Journal of The Korea Society of Computer and Information 27.1 pp.175-181 (2022) : 175.

Kim Mee Kyung. Anti-inflammatory Effect of Broccoli Leaf Hexane Fraction in LPS-stimulated RAW264.7 Cells. 2022; 27(1), 175-181. Available from: doi:10.9708/jksci.2022.27.01.175

Kim Mee Kyung. "Anti-inflammatory Effect of Broccoli Leaf Hexane Fraction in LPS-stimulated RAW264.7 Cells" Journal of The Korea Society of Computer and Information 27, no.1 (2022) : 175-181.doi: 10.9708/jksci.2022.27.01.175

Kim Mee Kyung. Anti-inflammatory Effect of Broccoli Leaf Hexane Fraction in LPS-stimulated RAW264.7 Cells. Journal of The Korea Society of Computer and Information, 27(1), 175-181. doi: 10.9708/jksci.2022.27.01.175

Kim Mee Kyung. Anti-inflammatory Effect of Broccoli Leaf Hexane Fraction in LPS-stimulated RAW264.7 Cells. Journal of The Korea Society of Computer and Information. 2022; 27(1) 175-181. doi: 10.9708/jksci.2022.27.01.175

Kim Mee Kyung. Anti-inflammatory Effect of Broccoli Leaf Hexane Fraction in LPS-stimulated RAW264.7 Cells. 2022; 27(1), 175-181. Available from: doi:10.9708/jksci.2022.27.01.175

Kim Mee Kyung. "Anti-inflammatory Effect of Broccoli Leaf Hexane Fraction in LPS-stimulated RAW264.7 Cells" Journal of The Korea Society of Computer and Information 27, no.1 (2022) : 175-181.doi: 10.9708/jksci.2022.27.01.175