A Treatment Guideline for Neuropathic Pain (신경병증성 통증의 치료 지침에 대한 고찰)

정국진; Lee, Jae Hyup (이재협); 황창주; 안면환

A Treatment Guideline for Neuropathic Pain

Journal of Korean Society of Spine Surgery
Abbr : J Kor Spine Sur
2011, 18(4), pp.246-253
Publisher : Korean Society Of Spine Surgery
Research Area : Medicine and Pharmacy > Orthopedic Surgery

정국진 ¹, Lee, Jae Hyup ², 황창주 ³, 안면환 ⁴

¹한림대학교
²서울대학교
³울산대학교
⁴영남대학교

Accredited

ABSTRACT

Study Design: A review of literature including definition, diagnosis and treatment of neuropathic pain. Objectives: To review and discuss the treatment guideline for neuropathic pain. Summary of Literature Review: Neuropathic pains are characterized by partial or complete somatosensory change caused by various disorders affecting central and peripheral nervous system, and are especially problematic because of their severity, chronicity and resistance to simple analgesics. Materials and Methods: Review of literature. Results: Tricyclic antidepressants and the anticonvulsants gabapentin and pregablin were recommended as first-line treatments for neuropathic pain. Opioid analgesics and tramadol were recommended as second-line treatments that can be considered for first-line use in selected clinical circumstances. Other medications such as dual reuptake inhibitors of both serotonin and norepinephrine would be used in severe cases. More invasive interventions (e.g., spinal cord stimulation) may sometimes be helpful. Conclusions: Treatment must be individualized for each patient and aggressive, combinatory pharmacotherapy and multidisciplinary approach are recommended for the treatment of neuropathic pain.

KEYWORDS

Neuropathic pain, Definition, Diagnosis, Treatment guideline

Citation status

* References for papers published after 2023 are currently being built.

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