@article{ART002211214},
author={Seung-Hwan Lee and Byeong-Mun Park and Kyung-Sub Song and Su-Keon Lee and 윤상필 and 이재철 and 이범석 and Bong-Seok Yang},
title={Risk Factors for Osteoporotic Vertebral Fracture in Cushing Syndrome},
journal={Journal of Korean Society of Spine Surgery},
issn={2093-4378},
year={2017},
volume={24},
number={1},
pages={1-6}
TY - JOUR
AU - Seung-Hwan Lee
AU - Byeong-Mun Park
AU - Kyung-Sub Song
AU - Su-Keon Lee
AU - 윤상필
AU - 이재철
AU - 이범석
AU - Bong-Seok Yang
TI - Risk Factors for Osteoporotic Vertebral Fracture in Cushing Syndrome
JO - Journal of Korean Society of Spine Surgery
PY - 2017
VL - 24
IS - 1
PB - Korean Society Of Spine Surgery
SP - 1
EP - 6
SN - 2093-4378
AB - Study design: Retrospective study.
Objectives: The goal of this study was to evaluate the risk factors of osteoporotic vertebral fractures (OVFs) in patients with Cushing syndrome.
Summary of Literature review: In most reports, vertebral fractures in Cushing syndrome have been found to be related to osteoporosis.
However, few studies have analyzed the clinical risk factors for OVFs.
Materials and Methods: Thirty-two patients with Cushing syndrome who visited the orthopaedic department complaining of back pain were included in this study. Standing lateral X-rays were performed to evaluate the presence of vertebral fractures, and bone mineral density (BMD) was measured.
Results: Of the 32 patients with Cushing syndrome with back pain, 8 (25%) were diagnosed with OVFs using morphometric criteria. The average weight and body mass index of the vertebral fracture group (VF group) were significantly higher than the values observed in the non-vertebral fracture group (non-VF group) (p=0.004, p=0.018). Lumbar BMD was significantly lower in the VF group (p=0.006). A risk factor for OVFs in Cushing syndrome was osteoporosis (odds ratio=18.56, 95% confidence interval=1.72-200.21, p=0.016) regardless of gender, obesity, menopause, or urine free cortisol levels.
Conclusions: OVFs in Cushing syndrome have been associated with overweight, and overweight is an indicator of compliance in the treatment of Cushing syndrome. Therefore, weight reduction and the prevention of osteoporosis should be emphasized in patients with Cushing syndrome to prevent OVFs.
KW - Cushing syndrome;Vertebral fracture;Osteoporosis
DO -
UR -
ER -
Seung-Hwan Lee, Byeong-Mun Park, Kyung-Sub Song, Su-Keon Lee, 윤상필, 이재철, 이범석 and Bong-Seok Yang. (2017). Risk Factors for Osteoporotic Vertebral Fracture in Cushing Syndrome. Journal of Korean Society of Spine Surgery, 24(1), 1-6.
Seung-Hwan Lee, Byeong-Mun Park, Kyung-Sub Song, Su-Keon Lee, 윤상필, 이재철, 이범석 and Bong-Seok Yang. 2017, "Risk Factors for Osteoporotic Vertebral Fracture in Cushing Syndrome", Journal of Korean Society of Spine Surgery, vol.24, no.1 pp.1-6.
Seung-Hwan Lee, Byeong-Mun Park, Kyung-Sub Song, Su-Keon Lee, 윤상필, 이재철, 이범석, Bong-Seok Yang "Risk Factors for Osteoporotic Vertebral Fracture in Cushing Syndrome" Journal of Korean Society of Spine Surgery 24.1 pp.1-6 (2017) : 1.
Seung-Hwan Lee, Byeong-Mun Park, Kyung-Sub Song, Su-Keon Lee, 윤상필, 이재철, 이범석, Bong-Seok Yang. Risk Factors for Osteoporotic Vertebral Fracture in Cushing Syndrome. 2017; 24(1), 1-6.
Seung-Hwan Lee, Byeong-Mun Park, Kyung-Sub Song, Su-Keon Lee, 윤상필, 이재철, 이범석 and Bong-Seok Yang. "Risk Factors for Osteoporotic Vertebral Fracture in Cushing Syndrome" Journal of Korean Society of Spine Surgery 24, no.1 (2017) : 1-6.
Seung-Hwan Lee; Byeong-Mun Park; Kyung-Sub Song; Su-Keon Lee; 윤상필; 이재철; 이범석; Bong-Seok Yang. Risk Factors for Osteoporotic Vertebral Fracture in Cushing Syndrome. Journal of Korean Society of Spine Surgery, 24(1), 1-6.
Seung-Hwan Lee; Byeong-Mun Park; Kyung-Sub Song; Su-Keon Lee; 윤상필; 이재철; 이범석; Bong-Seok Yang. Risk Factors for Osteoporotic Vertebral Fracture in Cushing Syndrome. Journal of Korean Society of Spine Surgery. 2017; 24(1) 1-6.
Seung-Hwan Lee, Byeong-Mun Park, Kyung-Sub Song, Su-Keon Lee, 윤상필, 이재철, 이범석, Bong-Seok Yang. Risk Factors for Osteoporotic Vertebral Fracture in Cushing Syndrome. 2017; 24(1), 1-6.
Seung-Hwan Lee, Byeong-Mun Park, Kyung-Sub Song, Su-Keon Lee, 윤상필, 이재철, 이범석 and Bong-Seok Yang. "Risk Factors for Osteoporotic Vertebral Fracture in Cushing Syndrome" Journal of Korean Society of Spine Surgery 24, no.1 (2017) : 1-6.