@article{ART001753068},
author={박수진 and 최영철 and 김진상},
title={The Effects of Exercise of Diverse Intensities on the Recovery of Articular Cartilage in Osteoarthritic Rats},
journal={Journal of the Korean Society of Physical Medicine},
issn={1975-311X},
year={2013},
volume={8},
number={1},
pages={127-135}
TY - JOUR
AU - 박수진
AU - 최영철
AU - 김진상
TI - The Effects of Exercise of Diverse Intensities on the Recovery of Articular Cartilage in Osteoarthritic Rats
JO - Journal of the Korean Society of Physical Medicine
PY - 2013
VL - 8
IS - 1
PB - The Korean Society of Physical Medicine
SP - 127
EP - 135
SN - 1975-311X
AB - PURPOSE: This study examined the effects of exercise of diverse intensities on the recovery of articular cartilage in osteoarthritic rats.
METHODS: Over a period of four weeks, the authors applied treadmill exercise programs of diverse intensities to Sprague-Dawley rats, to which intra-articular injection of monosodium iodoacetate(MIA, 3㎎/50㎕, diluted in saline)was applied to the right knee joint to induce osteoarthritis. The four-week exercise program was not carried out with the control group(CG, n=10). Exercise programs of applicable intensities were applied to the low-intensity exercise group(LEG,n=10), moderate-intensity exercise group(MEG, n=10), and high-intensity exercise group(HEG, n=10) over the four weeks. Observations were made of morphological changes in the rats’ articular cartilage, using hematoxylin and eosin stains.RESULTS: there were significant differences(p<.05) in the comparison of articular damage scores between the four groups involved. Articular cartilage damage scores were found to be significantly lower in the LEG, MEG, and HEG than in the CG, indicating that exercise helped with the recovery of cartilage. Of these latter three groups, the MEG showed the highest level of recovery, while the HEG showed the lowest.
CONCLUSION: These study results suggest that exercise is effective in treating OA. They also indicate that in prescribing exercise to treat osteoarthritic patients, exercise of moderate intensity is most suitable to patients’ physical conditions, rather than low or high intensity, maximizes, and so should be used to maximize the effects of therapy.
KW - Osteoarthritis;Articular cartilage;Exercise intensity
DO -
UR -
ER -
박수진, 최영철 and 김진상. (2013). The Effects of Exercise of Diverse Intensities on the Recovery of Articular Cartilage in Osteoarthritic Rats. Journal of the Korean Society of Physical Medicine, 8(1), 127-135.
박수진, 최영철 and 김진상. 2013, "The Effects of Exercise of Diverse Intensities on the Recovery of Articular Cartilage in Osteoarthritic Rats", Journal of the Korean Society of Physical Medicine, vol.8, no.1 pp.127-135.
박수진, 최영철, 김진상 "The Effects of Exercise of Diverse Intensities on the Recovery of Articular Cartilage in Osteoarthritic Rats" Journal of the Korean Society of Physical Medicine 8.1 pp.127-135 (2013) : 127.
박수진, 최영철, 김진상. The Effects of Exercise of Diverse Intensities on the Recovery of Articular Cartilage in Osteoarthritic Rats. 2013; 8(1), 127-135.
박수진, 최영철 and 김진상. "The Effects of Exercise of Diverse Intensities on the Recovery of Articular Cartilage in Osteoarthritic Rats" Journal of the Korean Society of Physical Medicine 8, no.1 (2013) : 127-135.
박수진; 최영철; 김진상. The Effects of Exercise of Diverse Intensities on the Recovery of Articular Cartilage in Osteoarthritic Rats. Journal of the Korean Society of Physical Medicine, 8(1), 127-135.
박수진; 최영철; 김진상. The Effects of Exercise of Diverse Intensities on the Recovery of Articular Cartilage in Osteoarthritic Rats. Journal of the Korean Society of Physical Medicine. 2013; 8(1) 127-135.
박수진, 최영철, 김진상. The Effects of Exercise of Diverse Intensities on the Recovery of Articular Cartilage in Osteoarthritic Rats. 2013; 8(1), 127-135.
박수진, 최영철 and 김진상. "The Effects of Exercise of Diverse Intensities on the Recovery of Articular Cartilage in Osteoarthritic Rats" Journal of the Korean Society of Physical Medicine 8, no.1 (2013) : 127-135.