@article{ART001509398},
author={정다영 and 하혜경 and 이호영 and 이진아 and Nam-Hun Lee and 이준경 and 황대선 and 신현규},
title={Stimulation of the Immune Response by Yanggyuksanhwa-tang},
journal={Journal of Sasang Constitution and Immune Medicine},
issn={1226-4075},
year={2010},
volume={22},
number={4},
pages={77-84}
TY - JOUR
AU - 정다영
AU - 하혜경
AU - 이호영
AU - 이진아
AU - Nam-Hun Lee
AU - 이준경
AU - 황대선
AU - 신현규
TI - Stimulation of the Immune Response by Yanggyuksanhwa-tang
JO - Journal of Sasang Constitution and Immune Medicine
PY - 2010
VL - 22
IS - 4
PB - The Society of Sasang Constitution and Immune Medicine
SP - 77
EP - 84
SN - 1226-4075
AB - 1. Objectives Yanggyuksanhwa-tang for Soyangin was applied to investigate the immunological activities on antigen (Ag)-specific or Ag-non-specific immune responses on murine macrophage cell line (RAW 264.7) and ovalbumin/aluminium (OVA/Alum)-immunized mice.
2. Methods This study were carried out in nitric oxide (NO) synthesis on RAW 264.7 cells and cellular proliferation on mouse splenocytes. C57BL/6 mice were immunized intraperitonially with OVA/Alum (100 μg/200 μg) on day 1, 8, and 15. Yanggyuksanhwa-tang was administrated to mice orally for 3 weeks from day 1. On day 22, OVA-, lipopolysaccharide (LPS)-, and concanavalin A (Con A)-stimulated splenocyte proliferation and antibodies (OVA-specific antibodies of the IgG, IgG1, and total IgM classes) in plasma were measured.
3. Results Yanggyuksanhwa-tang significantly enhanced cellular proliferation by LPS and Con A on splenocytes from OVA/Alum-immunized mice (p<.001). Yanggyuksanhwa-tang also significantly enhanced plasma OVA-specific IgG (p<.001), IgG1 (p<.001), and total IgM (p<.01) levels compared with the OVA/Alum group.
4. Conclusions These results suggested that Yanggyuksanhwa-tang for Soyangin could be used as immunopotent.
KW - Yanggyuksanhwa-tang (Lianggesanhuo-tang);Antibodies;LPS;Con A;OVA
DO -
UR -
ER -
정다영, 하혜경, 이호영, 이진아, Nam-Hun Lee, 이준경, 황대선 and 신현규. (2010). Stimulation of the Immune Response by Yanggyuksanhwa-tang. Journal of Sasang Constitution and Immune Medicine, 22(4), 77-84.
정다영, 하혜경, 이호영, 이진아, Nam-Hun Lee, 이준경, 황대선 and 신현규. 2010, "Stimulation of the Immune Response by Yanggyuksanhwa-tang", Journal of Sasang Constitution and Immune Medicine, vol.22, no.4 pp.77-84.
정다영, 하혜경, 이호영, 이진아, Nam-Hun Lee, 이준경, 황대선, 신현규 "Stimulation of the Immune Response by Yanggyuksanhwa-tang" Journal of Sasang Constitution and Immune Medicine 22.4 pp.77-84 (2010) : 77.
정다영, 하혜경, 이호영, 이진아, Nam-Hun Lee, 이준경, 황대선, 신현규. Stimulation of the Immune Response by Yanggyuksanhwa-tang. 2010; 22(4), 77-84.
정다영, 하혜경, 이호영, 이진아, Nam-Hun Lee, 이준경, 황대선 and 신현규. "Stimulation of the Immune Response by Yanggyuksanhwa-tang" Journal of Sasang Constitution and Immune Medicine 22, no.4 (2010) : 77-84.
정다영; 하혜경; 이호영; 이진아; Nam-Hun Lee; 이준경; 황대선; 신현규. Stimulation of the Immune Response by Yanggyuksanhwa-tang. Journal of Sasang Constitution and Immune Medicine, 22(4), 77-84.
정다영; 하혜경; 이호영; 이진아; Nam-Hun Lee; 이준경; 황대선; 신현규. Stimulation of the Immune Response by Yanggyuksanhwa-tang. Journal of Sasang Constitution and Immune Medicine. 2010; 22(4) 77-84.
정다영, 하혜경, 이호영, 이진아, Nam-Hun Lee, 이준경, 황대선, 신현규. Stimulation of the Immune Response by Yanggyuksanhwa-tang. 2010; 22(4), 77-84.
정다영, 하혜경, 이호영, 이진아, Nam-Hun Lee, 이준경, 황대선 and 신현규. "Stimulation of the Immune Response by Yanggyuksanhwa-tang" Journal of Sasang Constitution and Immune Medicine 22, no.4 (2010) : 77-84.
