@article{ART002008028},
author={임태형 and Park Hye Sun},
title={The Effects of GalGunSeunggi-tang (GST) on Mice Induced Allergic Contact Dermatitis (ACD) by DNCB},
journal={Journal of Sasang Constitution and Immune Medicine},
issn={1226-4075},
year={2015},
volume={27},
number={2},
pages={240-253},
doi={10.7730/JSCM.2015.27.2.}
TY - JOUR
AU - 임태형
AU - Park Hye Sun
TI - The Effects of GalGunSeunggi-tang (GST) on Mice Induced Allergic Contact Dermatitis (ACD) by DNCB
JO - Journal of Sasang Constitution and Immune Medicine
PY - 2015
VL - 27
IS - 2
PB - The Society of Sasang Constitution and Immune Medicine
SP - 240
EP - 253
SN - 1226-4075
AB - Objectives The aim of this study was to investigate the effects of GalGunSeungGi-Tang (GST) on allergic contact dermatitis (ACD) induced by 2,4-dintrochlorobenzone (DNCB) Methods In this study, The changes of body weight, ear weight, ear thickness, spleen weight, dorsum skin thickness, symptom score by eyesight, histological finding, proliferation rates of splenocyte in vitro and in vivo are investigated to check effects of GST. The mice are divided into four group; Normal (naive mice) , Control (DW administered), GST-L (GST 500mg/Kg/day administered), GST-H (GST 1,000mg/Kg/day administered).
Results GST inhibited weight of ear significantly (P < 0.05) and also thickness (P < 0.01). In addition, There are significant decrease in thickness of dorsum skin and proliferation rates of splenocyte in vivo in GST administered group. Finally, GST reduced symptom score and hyperkeratosis, hyperpigmentation, increase of granulocyte and parakeratosis in histological finding.
Conclusions These results suggest that GST can decrease symptoms of ACD.
KW - Sasang Constitutional Medicine;GalGunSeungGi-Tang;Allergic Contact Dermatitis;DNCB
DO - 10.7730/JSCM.2015.27.2.
ER -
임태형 and Park Hye Sun. (2015). The Effects of GalGunSeunggi-tang (GST) on Mice Induced Allergic Contact Dermatitis (ACD) by DNCB. Journal of Sasang Constitution and Immune Medicine, 27(2), 240-253.
임태형 and Park Hye Sun. 2015, "The Effects of GalGunSeunggi-tang (GST) on Mice Induced Allergic Contact Dermatitis (ACD) by DNCB", Journal of Sasang Constitution and Immune Medicine, vol.27, no.2 pp.240-253. Available from: doi:10.7730/JSCM.2015.27.2.
임태형, Park Hye Sun "The Effects of GalGunSeunggi-tang (GST) on Mice Induced Allergic Contact Dermatitis (ACD) by DNCB" Journal of Sasang Constitution and Immune Medicine 27.2 pp.240-253 (2015) : 240.
임태형, Park Hye Sun. The Effects of GalGunSeunggi-tang (GST) on Mice Induced Allergic Contact Dermatitis (ACD) by DNCB. 2015; 27(2), 240-253. Available from: doi:10.7730/JSCM.2015.27.2.
임태형 and Park Hye Sun. "The Effects of GalGunSeunggi-tang (GST) on Mice Induced Allergic Contact Dermatitis (ACD) by DNCB" Journal of Sasang Constitution and Immune Medicine 27, no.2 (2015) : 240-253.doi: 10.7730/JSCM.2015.27.2.
임태형; Park Hye Sun. The Effects of GalGunSeunggi-tang (GST) on Mice Induced Allergic Contact Dermatitis (ACD) by DNCB. Journal of Sasang Constitution and Immune Medicine, 27(2), 240-253. doi: 10.7730/JSCM.2015.27.2.
임태형; Park Hye Sun. The Effects of GalGunSeunggi-tang (GST) on Mice Induced Allergic Contact Dermatitis (ACD) by DNCB. Journal of Sasang Constitution and Immune Medicine. 2015; 27(2) 240-253. doi: 10.7730/JSCM.2015.27.2.
임태형, Park Hye Sun. The Effects of GalGunSeunggi-tang (GST) on Mice Induced Allergic Contact Dermatitis (ACD) by DNCB. 2015; 27(2), 240-253. Available from: doi:10.7730/JSCM.2015.27.2.
임태형 and Park Hye Sun. "The Effects of GalGunSeunggi-tang (GST) on Mice Induced Allergic Contact Dermatitis (ACD) by DNCB" Journal of Sasang Constitution and Immune Medicine 27, no.2 (2015) : 240-253.doi: 10.7730/JSCM.2015.27.2.