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Effects of CheongSimYeonJaTang(CSYJT) on Control of Immune-function in highly purified mouse B cells and Mast cell

  • Journal of Sasang Constitution and Immune Medicine
  • Abbr : JSCIM
  • 2003, 15(2), pp.166~179
  • Publisher : The Society of Sasang Constitution and Immune Medicine
  • Research Area : Medicine and Pharmacy > Korean Medicine
  • Received : August 31, 2003
  • Accepted : August 31, 2003
  • Published : August 30, 2003

Park Seung Chan 1

1대전대학교

ABSTRACT

In order to evaluate the antiallergic effects of CSYJT, studies were done. We measured the cytotoxic activity for cytokines transcript expression, production of IL-4, IgE, IFN−γ, proliferation of B cell in HRF plus anti-CD40mAb plus rIL-4 stimulated murine splenic B cells. and cytokines transcript expression of IgE in Mast cell The results were obtained as follows: 1. CSYJT decreased the expression of IL-4 in mast cell significantly. 2. CSYJT decreased the production of IL-4 significantly. 3. CSYJT decreased the expression of IgE in mast cell significantly. 4. CSYJT decreased the production of IgE significantly. 5. CSYJT increased the appearance of IFN−γ. The facts above prove that CSYJT is effective against the allergy. Thus, I think that we should study on this continuously.

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