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The Antimicrobial Activity of Bojungikgi-tang, Gwakhyangjeonggi-san, and Gunggwihyangso-san to Klebsiella pneumoniae 289 extracted from Allergic Rhinitis Patients

  • Journal of Sasang Constitution and Immune Medicine
  • Abbr : JSCIM
  • 2004, 16(3), pp.85-95
  • Publisher : The Society of Sasang Constitution and Immune Medicine
  • Research Area : Medicine and Pharmacy > Korean Medicine
  • Received : December 31, 2004
  • Accepted : December 31, 2004
  • Published : December 31, 2004

Suh Ji Yong 1 Seo Eun Hee 1 Park Suk Joon 1 Goo Deok Mo 1

1

ABSTRACT

1. Objectives Although the incidence of allergic rhinitis is increasing continually, Sasang Constitutional Medicine is showing favorable treatment outcomes. This study was aimed to test the antimicrobial effects of Bojungikgi-tang, Gwakhyangjeonggi-san, and Gunggwihyangso-san which are being applied to allergic rhinitis of Soeumin. 2. Methods Klebsiella pneumoniae 289 was extracted from allergic rhinitis patients. Bojungikgi-tang, Gwakhyangjeonggi-san, and Gunggwihyangso-san were boiled down and concentrated, and the substances obtained were tested for the effects on stability to temperature and pH and on antimicrobial activity 3. Results When measured the level of antimicrobial activity, the inhibition zones of Bojungikgi-tang, Gwakhyangjeonggi-san, and Gunggwihyangso-san were found 11.42, 11.07, and 10.63mm, respectively. The levels of MIC were 15㎕, 20 ㎕, and 10 ㎕ in that order. The antimicrobial activities were increased 13.88% in Bojungikgi-tang, 16.63% in Gwakhyangjeonggi-san, and 10.72% in Gunggwihyangso-san. There was no influence of pH to antimicrobial activity of all three substances. 4. Conclusions Bojungikgi-tang, Gwakhyangjeonggi-san, and Gunggwihyangso-san had a high level of antimicrobial activity to Klebsiella pneumoniae 289 even at a low concentration.

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