@article{ART001051432},
author={Kim Eun-young and Kim Hoon and Kim Jong Won and 설유경 and 최재중 and 전수형},
title={Effect of Cheongpesagan-tang on the Change of Inhibitory Effect against Lipase Activity and Weight Loss, Plasma and UCP1, 2 mRNA Expression in db/db Mouse},
journal={Journal of Sasang Constitution and Immune Medicine},
issn={1226-4075},
year={2007},
volume={19},
number={1},
pages={171-185}
TY - JOUR
AU - Kim Eun-young
AU - Kim Hoon
AU - Kim Jong Won
AU - 설유경
AU - 최재중
AU - 전수형
TI - Effect of Cheongpesagan-tang on the Change of Inhibitory Effect against Lipase Activity and Weight Loss, Plasma and UCP1, 2 mRNA Expression in db/db Mouse
JO - Journal of Sasang Constitution and Immune Medicine
PY - 2007
VL - 19
IS - 1
PB - The Society of Sasang Constitution and Immune Medicine
SP - 171
EP - 185
SN - 1226-4075
AB - Effect of Cheongpesagan-tang on the Change of Inhibitory Effect against Lipase Activity and Weight Loss, Plasma and UCP1, 2 mRNA Expression in db/db Mouse
Eun Young Kim, Yu kyung Sul, Jae Jung Choi, Soo Hyung Jeon, Hoon Kim*, Jong Won Kim
Dept. of Sasang Constitution Medicine, College of Oriental Medicine, Dongeui University
*Dept. of Oriental Medical History, Dongeui University
1. Objectvies
This experimental study was designed to investigate the effect of cheongpesagan-tang extract on the obstruction of the lipase activity and weight, plasma, UCP1, 2 mRNA in db/db mouse. Material and Methods: The body weight loss, food intake, feeding efficiency ratio, weight of the internal organs (liver, kidney, epididymal fat, brown adipose tissue), plasma glucose, triglyceride, total cholesterol, white adipose tissue, adipocyte size distribution, expression of UCP1, 2 mRNA were measured in db/db mouse administered Cheongpesagan-tang extract for 6 weeks. These were then compared with those of control groups administered the diet.
2. Results
1) Inhibitory effect against lipase activity was Kilgyung(81.7%), Nabokja (73.1%), Seungma(73.0%), Daewhang (68.4%), Kalgeun (55.3%), Kobon(34.5%), Hwanggeum(4.2%).
2) In the sample group, the body weight was significantly decrease than that of control group.
3) In the sample group, the weight of epididymal fat showed significantly decrease than that of control group.
4) In the sample group, triglyceride showed significantly decrease than that of control group.
5) In the sample group, distribution of adipose tissue showed significantly larger than that of control group.
6) In the sample group, UCP1, 2 mRNA in BAT showed significantly increase than that of control group.
3. Conclusions
These results show that cheongpesagan-tang has an effect on the treatment of obesity.
KW - Cheongpesagan-tang;Obesity;Lipase. UCP1;2
DO -
UR -
ER -
Kim Eun-young, Kim Hoon, Kim Jong Won, 설유경, 최재중 and 전수형. (2007). Effect of Cheongpesagan-tang on the Change of Inhibitory Effect against Lipase Activity and Weight Loss, Plasma and UCP1, 2 mRNA Expression in db/db Mouse. Journal of Sasang Constitution and Immune Medicine, 19(1), 171-185.
Kim Eun-young, Kim Hoon, Kim Jong Won, 설유경, 최재중 and 전수형. 2007, "Effect of Cheongpesagan-tang on the Change of Inhibitory Effect against Lipase Activity and Weight Loss, Plasma and UCP1, 2 mRNA Expression in db/db Mouse", Journal of Sasang Constitution and Immune Medicine, vol.19, no.1 pp.171-185.
Kim Eun-young, Kim Hoon, Kim Jong Won, 설유경, 최재중, 전수형 "Effect of Cheongpesagan-tang on the Change of Inhibitory Effect against Lipase Activity and Weight Loss, Plasma and UCP1, 2 mRNA Expression in db/db Mouse" Journal of Sasang Constitution and Immune Medicine 19.1 pp.171-185 (2007) : 171.
Kim Eun-young, Kim Hoon, Kim Jong Won, 설유경, 최재중, 전수형. Effect of Cheongpesagan-tang on the Change of Inhibitory Effect against Lipase Activity and Weight Loss, Plasma and UCP1, 2 mRNA Expression in db/db Mouse. 2007; 19(1), 171-185.
Kim Eun-young, Kim Hoon, Kim Jong Won, 설유경, 최재중 and 전수형. "Effect of Cheongpesagan-tang on the Change of Inhibitory Effect against Lipase Activity and Weight Loss, Plasma and UCP1, 2 mRNA Expression in db/db Mouse" Journal of Sasang Constitution and Immune Medicine 19, no.1 (2007) : 171-185.
Kim Eun-young; Kim Hoon; Kim Jong Won; 설유경; 최재중; 전수형. Effect of Cheongpesagan-tang on the Change of Inhibitory Effect against Lipase Activity and Weight Loss, Plasma and UCP1, 2 mRNA Expression in db/db Mouse. Journal of Sasang Constitution and Immune Medicine, 19(1), 171-185.
Kim Eun-young; Kim Hoon; Kim Jong Won; 설유경; 최재중; 전수형. Effect of Cheongpesagan-tang on the Change of Inhibitory Effect against Lipase Activity and Weight Loss, Plasma and UCP1, 2 mRNA Expression in db/db Mouse. Journal of Sasang Constitution and Immune Medicine. 2007; 19(1) 171-185.
Kim Eun-young, Kim Hoon, Kim Jong Won, 설유경, 최재중, 전수형. Effect of Cheongpesagan-tang on the Change of Inhibitory Effect against Lipase Activity and Weight Loss, Plasma and UCP1, 2 mRNA Expression in db/db Mouse. 2007; 19(1), 171-185.
Kim Eun-young, Kim Hoon, Kim Jong Won, 설유경, 최재중 and 전수형. "Effect of Cheongpesagan-tang on the Change of Inhibitory Effect against Lipase Activity and Weight Loss, Plasma and UCP1, 2 mRNA Expression in db/db Mouse" Journal of Sasang Constitution and Immune Medicine 19, no.1 (2007) : 171-185.