@article{ART001339606},
author={Hwayong Park and 유현주 and 구임희 and 김종열},
title={Short Tandem Repeat Allele Frequencies in Sasang Constitution},
journal={Journal of Sasang Constitutional Medicine},
issn={1226-4075},
year={2009},
volume={21},
number={1},
pages={227-236}
TY - JOUR
AU - Hwayong Park
AU - 유현주
AU - 구임희
AU - 김종열
TI - Short Tandem Repeat Allele Frequencies in Sasang Constitution
JO - Journal of Sasang Constitutional Medicine
PY - 2009
VL - 21
IS - 1
PB - The Society Of Sasang Constitutional Medicine
SP - 227
EP - 236
SN - 1226-4075
AB - 1. Objectives
As a basic trial for identification of Sasang constitutional gene marker, we genotyped and analysed statistical relationships of STR(short tandem repeat) alleles and its distribution in each constitution.
2. Methods
After obtaining basic constitutional data with questionnaire (QSCC II), decision of constitution was made by 3 different constitution specialists' diagnosis, and only the samples of specialists' agreement of each constitution by discussion were taken into this research. Using multiplex PCR kit, total 146 constitutional samples were amplified in 16 autosomal STR marker, genotyped, and analysed statistically. Among 16 markers, 15 were analysed in this study excluding the amelogenin marker is used for in gender identification.
3. Results and Conclusions
It is difficult to determine the relationship between constitution and STR marker as the sample size is small, however, Penta D and vWA were shown to be related statistically with constitution. It has been know that STRs has no genetic informations, however there are some recent research results showing STRs as a regulatory element, relationship between microsatellite instability and repeat number and size, and post-transcriptional sigualing. STRs which is not known about its function currently, are proposed to have function and/or regulatory activities anyhow with Sasang constitution. It is believed that the results of this study can halp determine and deatify the markers related to Sasang Constitutional Medicien.
KW - Sasang constitution;STR;Genotyping
DO -
UR -
ER -
Hwayong Park, 유현주, 구임희 and 김종열. (2009). Short Tandem Repeat Allele Frequencies in Sasang Constitution. Journal of Sasang Constitutional Medicine, 21(1), 227-236.
Hwayong Park, 유현주, 구임희 and 김종열. 2009, "Short Tandem Repeat Allele Frequencies in Sasang Constitution", Journal of Sasang Constitutional Medicine, vol.21, no.1 pp.227-236.
Hwayong Park, 유현주, 구임희, 김종열 "Short Tandem Repeat Allele Frequencies in Sasang Constitution" Journal of Sasang Constitutional Medicine 21.1 pp.227-236 (2009) : 227.
Hwayong Park, 유현주, 구임희, 김종열. Short Tandem Repeat Allele Frequencies in Sasang Constitution. 2009; 21(1), 227-236.
Hwayong Park, 유현주, 구임희 and 김종열. "Short Tandem Repeat Allele Frequencies in Sasang Constitution" Journal of Sasang Constitutional Medicine 21, no.1 (2009) : 227-236.
Hwayong Park; 유현주; 구임희; 김종열. Short Tandem Repeat Allele Frequencies in Sasang Constitution. Journal of Sasang Constitutional Medicine, 21(1), 227-236.
Hwayong Park; 유현주; 구임희; 김종열. Short Tandem Repeat Allele Frequencies in Sasang Constitution. Journal of Sasang Constitutional Medicine. 2009; 21(1) 227-236.
Hwayong Park, 유현주, 구임희, 김종열. Short Tandem Repeat Allele Frequencies in Sasang Constitution. 2009; 21(1), 227-236.
Hwayong Park, 유현주, 구임희 and 김종열. "Short Tandem Repeat Allele Frequencies in Sasang Constitution" Journal of Sasang Constitutional Medicine 21, no.1 (2009) : 227-236.
