@article{ART001339609},
author={마진열 and 황대선 and Siwoo Lee and 김종열 and 신현규},
title={Acute Toxicity Study on Yeoldahanso-tang in Mice},
journal={Journal of Sasang Constitutional Medicine},
issn={1226-4075},
year={2009},
volume={21},
number={1},
pages={247-253}
TY - JOUR
AU - 마진열
AU - 황대선
AU - Siwoo Lee
AU - 김종열
AU - 신현규
TI - Acute Toxicity Study on Yeoldahanso-tang in Mice
JO - Journal of Sasang Constitutional Medicine
PY - 2009
VL - 21
IS - 1
PB - The Society Of Sasang Constitutional Medicine
SP - 247
EP - 253
SN - 1226-4075
AB - 1. Objectives
This study was designed to andyze the acute toxicity and safety of Yeoldahanso-tang.
2. Methods
We investigated the acute toxicity for water-extracted Yeoldahanso-tang. 25 male and 25 female mice were observed for 14 days after one day oral administration of Yeoldahanso-tang at the respective doses of 0(control group), 2560, 3200, 4000 and 5000 ㎎/㎏.
3. Results
We observed survival rates, general toxicity, change of body weight and autopsy.
4. Conclusions
The data confirmed that Yeoldahanso-tang is free from the toxicity and safety problems in oral route respectively. Compared with the control group, we could not find any toxic alteration in all treated groups(2560, 3200, 4000 and 5000 ㎎/㎏). In conclusion, LD50 of Yeoldahanso-tang was over 5000 ㎎/㎏ and it is very safe to mice.
KW - Yeoldahanso-tang;acute toxicity;safety;LD50
DO -
UR -
ER -
마진열, 황대선, Siwoo Lee, 김종열 and 신현규. (2009). Acute Toxicity Study on Yeoldahanso-tang in Mice. Journal of Sasang Constitutional Medicine, 21(1), 247-253.
마진열, 황대선, Siwoo Lee, 김종열 and 신현규. 2009, "Acute Toxicity Study on Yeoldahanso-tang in Mice", Journal of Sasang Constitutional Medicine, vol.21, no.1 pp.247-253.
마진열, 황대선, Siwoo Lee, 김종열, 신현규 "Acute Toxicity Study on Yeoldahanso-tang in Mice" Journal of Sasang Constitutional Medicine 21.1 pp.247-253 (2009) : 247.
마진열, 황대선, Siwoo Lee, 김종열, 신현규. Acute Toxicity Study on Yeoldahanso-tang in Mice. 2009; 21(1), 247-253.
마진열, 황대선, Siwoo Lee, 김종열 and 신현규. "Acute Toxicity Study on Yeoldahanso-tang in Mice" Journal of Sasang Constitutional Medicine 21, no.1 (2009) : 247-253.
마진열; 황대선; Siwoo Lee; 김종열; 신현규. Acute Toxicity Study on Yeoldahanso-tang in Mice. Journal of Sasang Constitutional Medicine, 21(1), 247-253.
마진열; 황대선; Siwoo Lee; 김종열; 신현규. Acute Toxicity Study on Yeoldahanso-tang in Mice. Journal of Sasang Constitutional Medicine. 2009; 21(1) 247-253.
마진열, 황대선, Siwoo Lee, 김종열, 신현규. Acute Toxicity Study on Yeoldahanso-tang in Mice. 2009; 21(1), 247-253.
마진열, 황대선, Siwoo Lee, 김종열 and 신현규. "Acute Toxicity Study on Yeoldahanso-tang in Mice" Journal of Sasang Constitutional Medicine 21, no.1 (2009) : 247-253.
