@article{ART001646691},
author={장문희 and 최재송 and Nayoung, Bae and TaekWon ahn},
title={Effects Of TAM (Taraxacum mongolicum) On Th2 Cytokine Production In MC/9 Mast Cells},
journal={Journal of Sasang Constitution and Immune Medicine},
issn={1226-4075},
year={2012},
volume={24},
number={1},
pages={54-65}
TY - JOUR
AU - 장문희
AU - 최재송
AU - Nayoung, Bae
AU - TaekWon ahn
TI - Effects Of TAM (Taraxacum mongolicum) On Th2 Cytokine Production In MC/9 Mast Cells
JO - Journal of Sasang Constitution and Immune Medicine
PY - 2012
VL - 24
IS - 1
PB - The Society of Sasang Constitution and Immune Medicine
SP - 54
EP - 65
SN - 1226-4075
AB - 1. Objectives The purpose of this study is to investigate the effects of TAM (Taraxacum mongolicum) on Th2 cytokine production in MC/9 mast cells.
2. Methods The effects of TAM was analyzed by ELISA and Real-time PCR in MC/9 mast cells. Levels of IL-5, IL-13 were measured using enzyme-linked immunosorbent assays(ELISA). mRNA levels of IL-4, IL-5, IL-6, IL-13 were analyzed with Real-time PCR.
3. Results 1) TAM inhibited the IL-4 production significantly in comparison to PI-control group at concentration of 50 ㎍/㎖, 100 ㎍/㎖, 200 ㎍/㎖.
2) TAM inhibited the IL-13 production significantly in comparison to PI-control group at concentration of 50 ㎍/㎖, 100 ㎍/㎖, 200 ㎍/㎖.
3) TAM inhibited the IL-4 mRNA expression significantly in comparison to PI-control group at concentration of 100 ㎍/㎖.
4) TAM inhibited the IL-5 mRNA expression significantly in comparison to PI-control group at concentration of 50 ㎍/㎖, 100 ㎍/㎖.
5) TAM inhibited the IL-6 mRNA expression significantly in comparison to PI-control group at concentration of 100 ㎍/㎖.
6) TAM inhibited the IL-13 mRNA expression significantly in comparison to PI-control group at concentration of 100 ㎍/㎖.
4. Conclusion These results indicate that TAM (Taraxacum mongolicum) has the effect of decreasing the Th2 cytokine production in the MC/9 mast cell.
KW - TAM (Taraxacum mongolicum);Cytokine;MC/9 Mast Cell;Atopic Dermatitis.
DO -
UR -
ER -
장문희, 최재송, Nayoung, Bae and TaekWon ahn. (2012). Effects Of TAM (Taraxacum mongolicum) On Th2 Cytokine Production In MC/9 Mast Cells. Journal of Sasang Constitution and Immune Medicine, 24(1), 54-65.
장문희, 최재송, Nayoung, Bae and TaekWon ahn. 2012, "Effects Of TAM (Taraxacum mongolicum) On Th2 Cytokine Production In MC/9 Mast Cells", Journal of Sasang Constitution and Immune Medicine, vol.24, no.1 pp.54-65.
장문희, 최재송, Nayoung, Bae, TaekWon ahn "Effects Of TAM (Taraxacum mongolicum) On Th2 Cytokine Production In MC/9 Mast Cells" Journal of Sasang Constitution and Immune Medicine 24.1 pp.54-65 (2012) : 54.
장문희, 최재송, Nayoung, Bae, TaekWon ahn. Effects Of TAM (Taraxacum mongolicum) On Th2 Cytokine Production In MC/9 Mast Cells. 2012; 24(1), 54-65.
장문희, 최재송, Nayoung, Bae and TaekWon ahn. "Effects Of TAM (Taraxacum mongolicum) On Th2 Cytokine Production In MC/9 Mast Cells" Journal of Sasang Constitution and Immune Medicine 24, no.1 (2012) : 54-65.
장문희; 최재송; Nayoung, Bae; TaekWon ahn. Effects Of TAM (Taraxacum mongolicum) On Th2 Cytokine Production In MC/9 Mast Cells. Journal of Sasang Constitution and Immune Medicine, 24(1), 54-65.
장문희; 최재송; Nayoung, Bae; TaekWon ahn. Effects Of TAM (Taraxacum mongolicum) On Th2 Cytokine Production In MC/9 Mast Cells. Journal of Sasang Constitution and Immune Medicine. 2012; 24(1) 54-65.
장문희, 최재송, Nayoung, Bae, TaekWon ahn. Effects Of TAM (Taraxacum mongolicum) On Th2 Cytokine Production In MC/9 Mast Cells. 2012; 24(1), 54-65.
장문희, 최재송, Nayoung, Bae and TaekWon ahn. "Effects Of TAM (Taraxacum mongolicum) On Th2 Cytokine Production In MC/9 Mast Cells" Journal of Sasang Constitution and Immune Medicine 24, no.1 (2012) : 54-65.