@article{ART002707474},
author={Ok Yun-young and Ryu Do Gon and kim kyung yo},
title={Effects of Taeumin Chungsimyeunjatang on the Cerebral neurons injured by Hydrogen Peroxide},
journal={Journal of Sasang Constitution and Immune Medicine},
issn={1226-4075},
year={1999},
volume={11},
number={2},
pages={251-266}
TY - JOUR
AU - Ok Yun-young
AU - Ryu Do Gon
AU - kim kyung yo
TI - Effects of Taeumin Chungsimyeunjatang on the Cerebral neurons injured by Hydrogen Peroxide
JO - Journal of Sasang Constitution and Immune Medicine
PY - 1999
VL - 11
IS - 2
PB - The Society of Sasang Constitution and Immune Medicine
SP - 251
EP - 266
SN - 1226-4075
AB - 1. Purpose : The purpose of this study was to determine the effects of Chungsimyeunjatang on the cerebral neurons injured by hydrogen peroxide(H₂O₂).
2. Methods : I observed cell viability in mouse cerebral neurons exposed to hydrogen peroxide by NR assay and MTT assay and determined lipid peroxidation and amounts of LDH release in mouse cerebral neurons exposed to hydrogen peroxide.
After administration of Chungsimyeunjatang water extracts, I observed significant changes of cell viability, lipid peroxidation and amounts of LDH release in mouse cerebral neurons exposed to hydrogen peroxide.
3. Results : Hydrogen peroxide showed neurotoxicity.
Cell viability in mouse cerebral neurons exposed to hydrogen peroxide decreased in NR assay and MTT assay.
Lipid peroxidation and amounts of LDH release in mouse cerebral neurons exposed to hydrogen peroxide increased.
Chungsimyeunjatang was very effective in blocking hydrogen peroxide-induced neurotoxicity.
KW - Chungsimyeunjatang;hydrogen peroxide;cell viability
DO -
UR -
ER -
Ok Yun-young, Ryu Do Gon and kim kyung yo. (1999). Effects of Taeumin Chungsimyeunjatang on the Cerebral neurons injured by Hydrogen Peroxide. Journal of Sasang Constitution and Immune Medicine, 11(2), 251-266.
Ok Yun-young, Ryu Do Gon and kim kyung yo. 1999, "Effects of Taeumin Chungsimyeunjatang on the Cerebral neurons injured by Hydrogen Peroxide", Journal of Sasang Constitution and Immune Medicine, vol.11, no.2 pp.251-266.
Ok Yun-young, Ryu Do Gon, kim kyung yo "Effects of Taeumin Chungsimyeunjatang on the Cerebral neurons injured by Hydrogen Peroxide" Journal of Sasang Constitution and Immune Medicine 11.2 pp.251-266 (1999) : 251.
Ok Yun-young, Ryu Do Gon, kim kyung yo. Effects of Taeumin Chungsimyeunjatang on the Cerebral neurons injured by Hydrogen Peroxide. 1999; 11(2), 251-266.
Ok Yun-young, Ryu Do Gon and kim kyung yo. "Effects of Taeumin Chungsimyeunjatang on the Cerebral neurons injured by Hydrogen Peroxide" Journal of Sasang Constitution and Immune Medicine 11, no.2 (1999) : 251-266.
Ok Yun-young; Ryu Do Gon; kim kyung yo. Effects of Taeumin Chungsimyeunjatang on the Cerebral neurons injured by Hydrogen Peroxide. Journal of Sasang Constitution and Immune Medicine, 11(2), 251-266.
Ok Yun-young; Ryu Do Gon; kim kyung yo. Effects of Taeumin Chungsimyeunjatang on the Cerebral neurons injured by Hydrogen Peroxide. Journal of Sasang Constitution and Immune Medicine. 1999; 11(2) 251-266.
Ok Yun-young, Ryu Do Gon, kim kyung yo. Effects of Taeumin Chungsimyeunjatang on the Cerebral neurons injured by Hydrogen Peroxide. 1999; 11(2), 251-266.
Ok Yun-young, Ryu Do Gon and kim kyung yo. "Effects of Taeumin Chungsimyeunjatang on the Cerebral neurons injured by Hydrogen Peroxide" Journal of Sasang Constitution and Immune Medicine 11, no.2 (1999) : 251-266.