본문 바로가기
  • Home

Effects of Taeyeumjoweetang against Glucose Oxidase-induced Neurotoxicity in the Cultured Mouse Cerebral Cortical Neurons

  • Journal of Sasang Constitutional Medicine
  • Abbr : J Sasang Constitut Med
  • 1999, 11(2), pp.267-281
  • Publisher : The Society Of Sasang Constitutional Medicine
  • Research Area : Medicine and Pharmacy > Korean Medicine
  • Received : December 31, 1999
  • Accepted : December 31, 1999
  • Published : December 31, 1999

Kim Jong-kwan 1 Ryu Do Gon 2 kim kyung yo 2

1원광대학교 한의과대학 사상의학교실
2원광대학교

ABSTRACT

1. Purpose : The purpose of this study was to determine the effects of Taeyeumjoweetang on the cerebral neurons injured by glucose oxidase(GO). 2. Methods : I observed cell viability in mouse cerebral neurons exposed to glucose oxidase by NR assay and MTT assay and determined lipid peroxidation in mouse cerebral neurons exposed to glucose oxidase. After administration of Taeyeumjoweetang water extracts, I observed significant changes of cell viability, lipid peroxidation in mouse cerebral neurons exposed to glucose oxidase. 3. Results : GO induced cell degeneration such as the decrease of cell viability was measured by MTT and NR assay in the cultured mouse cerebral cortical neurons. Taeyeumjoweetang was effective in the increase of total protein of neurons inhibited by GO. Taeyeumjoweetang was effective in the decrease of lipid peroxidation of neurons produced by GO.

Citation status

* References for papers published after 2022 are currently being built.