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The effect of Taeumjowetang and Herba Ephedrae on the Obese mRNA and TNF-α mRNA in obesity-induced rats

  • Journal of Sasang Constitution and Immune Medicine
  • Abbr : J Sasang Constitut Med
  • 2001, 13(1), pp.79-87
  • Publisher : The Society of Sasang Constitution and Immune Medicine
  • Research Area : Medicine and Pharmacy > Korean Medicine
  • Received : June 30, 2001
  • Accepted : June 30, 2001
  • Published : June 30, 2001

Shin Dong-jun 1 Dal Rae Kim 1 Kim Sun Hyung 2

1상지대학교 한의과대학 사상체질의학교실
2상지대학교

ABSTRACT

In order to investigate the effect of Taeumjowetang and Herba Ephedrae on obesity-induced rats, after Taeumjowetang and Herba Ephedrae were administered by mouth, and then body-weight, serum triglyceride, total cholesterol, Obese mRNA and TNF-α mRNA were measured. The reselts were as follows ; 1. The body-weight was decresed with the statistical significance in both the Taeumjowetang and the Herba Ephedrae group as compared with the control group. 2. The quantitation of serum triglyceride was decresed with the statistical significance in both the Taeumjowetang and the Herba Ephedrae group as compared with the control group. 3. The total cholesterol was slightly decresed in both the Taeumjowetang and the Herba Ephedrae group as compared with the control group, but there was no statistical significance. 4. The manifestation of Obese mRNA and TNF-α mRNA in epidymal, retroperitoneal, mesenteric and skeletal muscle tissues were inhibited in Taeumjowetang and Herba Ephedrae group. According to the above results, Taeumjowerang and Herba Ephedrae were recognized to be helpful for the treatment of obesity.

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