@article{ART002713029},
author={Hong Jeon-a and kim kyung yo and Ryu Do Gon and Park Hye Sun and Kim Hyoung-soon},
title={Effects of Yuldahansotang water extract on Cultured Spinal Sensory Neurons Damaged by Xanthine Oxidase/Hypoxanthine},
journal={Journal of Sasang Constitution and Immune Medicine},
issn={1226-4075},
year={2001},
volume={13},
number={1},
pages={88-96}
TY - JOUR
AU - Hong Jeon-a
AU - kim kyung yo
AU - Ryu Do Gon
AU - Park Hye Sun
AU - Kim Hyoung-soon
TI - Effects of Yuldahansotang water extract on Cultured Spinal Sensory Neurons Damaged by Xanthine Oxidase/Hypoxanthine
JO - Journal of Sasang Constitution and Immune Medicine
PY - 2001
VL - 13
IS - 1
PB - The Society of Sasang Constitution and Immune Medicine
SP - 88
EP - 96
SN - 1226-4075
AB - To evaluate the effect of Yuldahansotang(YHT) water extract on cultuted mouse spinal sensory neuron which was inhibited by xanthine oxidase(XO) and hypoxanthine(HX)-induced oxigen radicals, MIT assay, NR assay, Neurofilament enzymeimmuno assay and LDH activity assay were carried our after the cultured mouse spinal sensory neuron were preincubated with various concentrations of YHT water extract for 3 hours prior to exposure of XO/HX.
The results obtained were as follows: 1. XO/HX, a oxigen radical, decreased the survival rate of the cultured mouse spinal sensory neuron cells on NR assay and MTT assay.
2. MTT50 value and NR50 value pf XO/HX were 20 mU/ml XO/0.2 mM HX and 40 mU/ml XO/0.2 mM HX.
3. YHT water extract have efficacy of increasing neurofilament.
4. YHT water extract have efficacy of increasing LDH activity.
From above the results, It is concluded that YHT has marked efficacy as a treatment for the damages caused in the XO/HX-mediated oxidative process.
KW - Xanthine Oxidase(XO);Hypoxanthine(HX);MTT;NR;Yuldahansotang(YHT);Neurofilament;LDH activity
DO -
UR -
ER -
Hong Jeon-a, kim kyung yo, Ryu Do Gon, Park Hye Sun and Kim Hyoung-soon. (2001). Effects of Yuldahansotang water extract on Cultured Spinal Sensory Neurons Damaged by Xanthine Oxidase/Hypoxanthine. Journal of Sasang Constitution and Immune Medicine, 13(1), 88-96.
Hong Jeon-a, kim kyung yo, Ryu Do Gon, Park Hye Sun and Kim Hyoung-soon. 2001, "Effects of Yuldahansotang water extract on Cultured Spinal Sensory Neurons Damaged by Xanthine Oxidase/Hypoxanthine", Journal of Sasang Constitution and Immune Medicine, vol.13, no.1 pp.88-96.
Hong Jeon-a, kim kyung yo, Ryu Do Gon, Park Hye Sun, Kim Hyoung-soon "Effects of Yuldahansotang water extract on Cultured Spinal Sensory Neurons Damaged by Xanthine Oxidase/Hypoxanthine" Journal of Sasang Constitution and Immune Medicine 13.1 pp.88-96 (2001) : 88.
Hong Jeon-a, kim kyung yo, Ryu Do Gon, Park Hye Sun, Kim Hyoung-soon. Effects of Yuldahansotang water extract on Cultured Spinal Sensory Neurons Damaged by Xanthine Oxidase/Hypoxanthine. 2001; 13(1), 88-96.
Hong Jeon-a, kim kyung yo, Ryu Do Gon, Park Hye Sun and Kim Hyoung-soon. "Effects of Yuldahansotang water extract on Cultured Spinal Sensory Neurons Damaged by Xanthine Oxidase/Hypoxanthine" Journal of Sasang Constitution and Immune Medicine 13, no.1 (2001) : 88-96.
Hong Jeon-a; kim kyung yo; Ryu Do Gon; Park Hye Sun; Kim Hyoung-soon. Effects of Yuldahansotang water extract on Cultured Spinal Sensory Neurons Damaged by Xanthine Oxidase/Hypoxanthine. Journal of Sasang Constitution and Immune Medicine, 13(1), 88-96.
Hong Jeon-a; kim kyung yo; Ryu Do Gon; Park Hye Sun; Kim Hyoung-soon. Effects of Yuldahansotang water extract on Cultured Spinal Sensory Neurons Damaged by Xanthine Oxidase/Hypoxanthine. Journal of Sasang Constitution and Immune Medicine. 2001; 13(1) 88-96.
Hong Jeon-a, kim kyung yo, Ryu Do Gon, Park Hye Sun, Kim Hyoung-soon. Effects of Yuldahansotang water extract on Cultured Spinal Sensory Neurons Damaged by Xanthine Oxidase/Hypoxanthine. 2001; 13(1), 88-96.
Hong Jeon-a, kim kyung yo, Ryu Do Gon, Park Hye Sun and Kim Hyoung-soon. "Effects of Yuldahansotang water extract on Cultured Spinal Sensory Neurons Damaged by Xanthine Oxidase/Hypoxanthine" Journal of Sasang Constitution and Immune Medicine 13, no.1 (2001) : 88-96.
