@article{ART002743410},
author={Han Sung Kyu and Chi, Sang-Eun and SunMi Choi},
title={A Study on the analysis of constitutional genes},
journal={Journal of Sasang Constitution and Immune Medicine},
issn={1226-4075},
year={2003},
volume={15},
number={1},
pages={109-117}
TY - JOUR
AU - Han Sung Kyu
AU - Chi, Sang-Eun
AU - SunMi Choi
TI - A Study on the analysis of constitutional genes
JO - Journal of Sasang Constitution and Immune Medicine
PY - 2003
VL - 15
IS - 1
PB - The Society of Sasang Constitution and Immune Medicine
SP - 109
EP - 117
SN - 1226-4075
AB - There have been several the reports that the mechanism of Sasang consititution might be understood in the level of genes. Previous study of the authors showed that HLA types and constitutional information had significant relationships. One hundred subjects who showed Taeum characteristics were selected in the present study. HLA-A, HLA-B, HLA-DRB1, ACE, ${\beta}-IIAR$, ${\beta}-IIIAR$, UCP-1, and ALDH2 polymorphisms were analyzed. Also, ACE, ${\beta}-IIAR$, ${\beta}-IIIAR$, UCP-1, and ALDH2 analyses were performed on the 100 samples of previous study who showed Taeyang characteristics. Despite of several significant differences of HLA allele frequencies between Taeum-inclined group and normal control group, this significance level was not sufficient ro support the association between constitution and HLA genes, because of the raised alpha error rate. The polymorphisrns of ACE, ${\beta}-IIAR$, ${\beta}-IIIAR$, UCP-1, and ALDH2 genes did not show relationship between Taeyang-inclined and Taeum-inclined groups, whereas BMI showed difference between Taeyang-inclined and Taeum-inclined groups. ALDH2 in Taeyang-inclined group confirmed the protective role of ALDH2*2 allele against alcoholism.
KW - constitution;HLA;ACE;β−IIAR;β−IIIAR;UCP-1;ALDH2;BMI
DO -
UR -
ER -
Han Sung Kyu, Chi, Sang-Eun and SunMi Choi. (2003). A Study on the analysis of constitutional genes. Journal of Sasang Constitution and Immune Medicine, 15(1), 109-117.
Han Sung Kyu, Chi, Sang-Eun and SunMi Choi. 2003, "A Study on the analysis of constitutional genes", Journal of Sasang Constitution and Immune Medicine, vol.15, no.1 pp.109-117.
Han Sung Kyu, Chi, Sang-Eun, SunMi Choi "A Study on the analysis of constitutional genes" Journal of Sasang Constitution and Immune Medicine 15.1 pp.109-117 (2003) : 109.
Han Sung Kyu, Chi, Sang-Eun, SunMi Choi. A Study on the analysis of constitutional genes. 2003; 15(1), 109-117.
Han Sung Kyu, Chi, Sang-Eun and SunMi Choi. "A Study on the analysis of constitutional genes" Journal of Sasang Constitution and Immune Medicine 15, no.1 (2003) : 109-117.
Han Sung Kyu; Chi, Sang-Eun; SunMi Choi. A Study on the analysis of constitutional genes. Journal of Sasang Constitution and Immune Medicine, 15(1), 109-117.
Han Sung Kyu; Chi, Sang-Eun; SunMi Choi. A Study on the analysis of constitutional genes. Journal of Sasang Constitution and Immune Medicine. 2003; 15(1) 109-117.
Han Sung Kyu, Chi, Sang-Eun, SunMi Choi. A Study on the analysis of constitutional genes. 2003; 15(1), 109-117.
Han Sung Kyu, Chi, Sang-Eun and SunMi Choi. "A Study on the analysis of constitutional genes" Journal of Sasang Constitution and Immune Medicine 15, no.1 (2003) : 109-117.