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@article{ART001143077},
author={김현진 and 강지혜 and 이승호 and 유선열 and 김민석 and 김원재 and 정지연 and 전수경 and SUN-HUN KIM and 이은주},
title={Effects of Chorda-lingual Denervation on NOS Expression in the Rat Submandibular Gland},
journal={Anatomy & Biological Anthropology},
issn={2671-5651},
year={2007},
volume={20},
number={1},
pages={59-68},
doi={10.11637/aba.2007.20.1.59}

TY - JOUR
AU - 김현진
AU - 강지혜
AU - 이승호
AU - 유선열
AU - 김민석
AU - 김원재
AU - 정지연
AU - 전수경
AU - SUN-HUN KIM
AU - 이은주
TI - Effects of Chorda-lingual Denervation on NOS Expression in the Rat Submandibular Gland
JO - Anatomy & Biological Anthropology
PY - 2007
VL - 20
IS - 1
PB - 대한체질인류학회
SP - 59
EP - 68
SN - 2671-5651
AB - Nitric oxide (NO) gas has been recognized to diffuse readily across the membrane and bind directly to molecule (s) inside target cells. In the salivary gland, eNOS and nNOS are constitutively expressed. iNOS was also reported to express in neoplastic salivary tissues. Regarding the role of NO in the salivary gland, it has been suggested that it may control blood flow to the glands and furthermore involve in growth and development of the gland. The present study hypothesized that denervation of parasympathetic secretomotor fibers may lead to salivary secretion dysfunction, changing NOS expression. The gland weight on the denervated side significantly decreased from 3 days after the denervation, comparing the control (p⁄0.01). Some atrophic and hyperchromatic changes, but no inflammatory reactions were found for the whole period of the experiment. All three kinds of NOS were mainly expressed in the ducts of the gland in both the control and experimental sides. Immunoreactivities of nNOS and eNOS were not noticeably different from those of the control. However, iNOS was also detected in ducts in the normal submandibular gland by immunohistochemical staining. The iNOS expression increased more than 2 times at denervated side of the gland than the control. These results suggest that NOS isoforms, especially iNOS following chorda-lingual denervation may lead to matrix loss or cell death in the salivary gland.
KW - Chorda-lingual denervation;NOS;Submandibular gland
DO - 10.11637/aba.2007.20.1.59
ER -

김현진, 강지혜, 이승호, 유선열, 김민석, 김원재, 정지연, 전수경, SUN-HUN KIM and 이은주. (2007). Effects of Chorda-lingual Denervation on NOS Expression in the Rat Submandibular Gland. Anatomy & Biological Anthropology, 20(1), 59-68.

김현진, 강지혜, 이승호, 유선열, 김민석, 김원재, 정지연, 전수경, SUN-HUN KIM and 이은주. 2007, "Effects of Chorda-lingual Denervation on NOS Expression in the Rat Submandibular Gland", Anatomy & Biological Anthropology, vol.20, no.1 pp.59-68. Available from: doi:10.11637/aba.2007.20.1.59

김현진, 강지혜, 이승호, 유선열, 김민석, 김원재, 정지연, 전수경, SUN-HUN KIM, 이은주 "Effects of Chorda-lingual Denervation on NOS Expression in the Rat Submandibular Gland" Anatomy & Biological Anthropology 20.1 pp.59-68 (2007) : 59.

김현진, 강지혜, 이승호, 유선열, 김민석, 김원재, 정지연, 전수경, SUN-HUN KIM, 이은주. Effects of Chorda-lingual Denervation on NOS Expression in the Rat Submandibular Gland. 2007; 20(1), 59-68. Available from: doi:10.11637/aba.2007.20.1.59

김현진, 강지혜, 이승호, 유선열, 김민석, 김원재, 정지연, 전수경, SUN-HUN KIM and 이은주. "Effects of Chorda-lingual Denervation on NOS Expression in the Rat Submandibular Gland" Anatomy & Biological Anthropology 20, no.1 (2007) : 59-68.doi: 10.11637/aba.2007.20.1.59

김현진; 강지혜; 이승호; 유선열; 김민석; 김원재; 정지연; 전수경; SUN-HUN KIM; 이은주. Effects of Chorda-lingual Denervation on NOS Expression in the Rat Submandibular Gland. Anatomy & Biological Anthropology, 20(1), 59-68. doi: 10.11637/aba.2007.20.1.59

김현진; 강지혜; 이승호; 유선열; 김민석; 김원재; 정지연; 전수경; SUN-HUN KIM; 이은주. Effects of Chorda-lingual Denervation on NOS Expression in the Rat Submandibular Gland. Anatomy & Biological Anthropology. 2007; 20(1) 59-68. doi: 10.11637/aba.2007.20.1.59

김현진, 강지혜, 이승호, 유선열, 김민석, 김원재, 정지연, 전수경, SUN-HUN KIM, 이은주. Effects of Chorda-lingual Denervation on NOS Expression in the Rat Submandibular Gland. 2007; 20(1), 59-68. Available from: doi:10.11637/aba.2007.20.1.59

김현진, 강지혜, 이승호, 유선열, 김민석, 김원재, 정지연, 전수경, SUN-HUN KIM and 이은주. "Effects of Chorda-lingual Denervation on NOS Expression in the Rat Submandibular Gland" Anatomy & Biological Anthropology 20, no.1 (2007) : 59-68.doi: 10.11637/aba.2007.20.1.59