@article{ART001753178},
author={권혁제 and 윤경식 and HAN-SUNG JUNG},
title={Expression Patterns of Ki-67, Cyclin A, and Cyclin D1 during Tooth Development},
journal={Anatomy & Biological Anthropology},
issn={2671-5651},
year={2013},
volume={26},
number={1},
pages={41-49},
doi={10.11637/aba.2013.26.1.41}
TY - JOUR
AU - 권혁제
AU - 윤경식
AU - HAN-SUNG JUNG
TI - Expression Patterns of Ki-67, Cyclin A, and Cyclin D1 during Tooth Development
JO - Anatomy & Biological Anthropology
PY - 2013
VL - 26
IS - 1
PB - 대한체질인류학회
SP - 41
EP - 49
SN - 2671-5651
AB - Dental epithelial and mesenchymal cells that form the teeth undergo dynamic changes in cell cycle during tooth development and morphogenesis. Although proliferation has been known as a key event during odontogenesis, the cell cycle phases and their relations with the complicated molecular mechanisms of tooth development are not fully understood yet. This study comparatively examined the expression patterns of Ki-67,cyclin A, and cyclin D1 during tooth development in the mouse incisor and molar in order to identify the cellcycle characteristics during odontogenesis. We found that Ki-67 and cyclin A were expressed in the proliferating cells in the dental epithelial and mesenchymal tissues at the bud, cap and bell stages. Cycln D1 showed distinct expression in the incisor odontoblast region and the enamel knot, in which Ki-67 nor cyclin A was expressed. Our results provide specific information on the cell cycle phases during tooth development that may provide clues to relate them with the complex odontogenic mechanisms. Furthermore, we suggest that our findings enlightened the previous studies on the incisor odontoblasts and the enamel knot during tooth development.
KW - Cell cycle;Ki-67;Cyclin A;Cyclin D1;Tooth development
DO - 10.11637/aba.2013.26.1.41
ER -
권혁제, 윤경식 and HAN-SUNG JUNG. (2013). Expression Patterns of Ki-67, Cyclin A, and Cyclin D1 during Tooth Development. Anatomy & Biological Anthropology, 26(1), 41-49.
권혁제, 윤경식 and HAN-SUNG JUNG. 2013, "Expression Patterns of Ki-67, Cyclin A, and Cyclin D1 during Tooth Development", Anatomy & Biological Anthropology, vol.26, no.1 pp.41-49. Available from: doi:10.11637/aba.2013.26.1.41
권혁제, 윤경식, HAN-SUNG JUNG "Expression Patterns of Ki-67, Cyclin A, and Cyclin D1 during Tooth Development" Anatomy & Biological Anthropology 26.1 pp.41-49 (2013) : 41.
권혁제, 윤경식, HAN-SUNG JUNG. Expression Patterns of Ki-67, Cyclin A, and Cyclin D1 during Tooth Development. 2013; 26(1), 41-49. Available from: doi:10.11637/aba.2013.26.1.41
권혁제, 윤경식 and HAN-SUNG JUNG. "Expression Patterns of Ki-67, Cyclin A, and Cyclin D1 during Tooth Development" Anatomy & Biological Anthropology 26, no.1 (2013) : 41-49.doi: 10.11637/aba.2013.26.1.41
권혁제; 윤경식; HAN-SUNG JUNG. Expression Patterns of Ki-67, Cyclin A, and Cyclin D1 during Tooth Development. Anatomy & Biological Anthropology, 26(1), 41-49. doi: 10.11637/aba.2013.26.1.41
권혁제; 윤경식; HAN-SUNG JUNG. Expression Patterns of Ki-67, Cyclin A, and Cyclin D1 during Tooth Development. Anatomy & Biological Anthropology. 2013; 26(1) 41-49. doi: 10.11637/aba.2013.26.1.41
권혁제, 윤경식, HAN-SUNG JUNG. Expression Patterns of Ki-67, Cyclin A, and Cyclin D1 during Tooth Development. 2013; 26(1), 41-49. Available from: doi:10.11637/aba.2013.26.1.41
권혁제, 윤경식 and HAN-SUNG JUNG. "Expression Patterns of Ki-67, Cyclin A, and Cyclin D1 during Tooth Development" Anatomy & Biological Anthropology 26, no.1 (2013) : 41-49.doi: 10.11637/aba.2013.26.1.41
