@article{ART003322338},
author={정아인 and Yoon-Young Chung and Hwang Hyo In and 신혜경 and YONGHYUN JUN},
title={Understanding the Diverse Mechanisms of Stroke: Excitotoxiicty, Cell Death, and Inflammation},
journal={Anatomy & Biological Anthropology},
issn={2671-5651},
year={2026},
volume={39},
number={1},
pages={31-35},
doi={10.11637/aba.2026.39.1.31}
TY - JOUR
AU - 정아인
AU - Yoon-Young Chung
AU - Hwang Hyo In
AU - 신혜경
AU - YONGHYUN JUN
TI - Understanding the Diverse Mechanisms of Stroke: Excitotoxiicty, Cell Death, and Inflammation
JO - Anatomy & Biological Anthropology
PY - 2026
VL - 39
IS - 1
PB - 대한체질인류학회
SP - 31
EP - 35
SN - 2671-5651
AB - stroke remains one of the most challenging neurological conditions worldwide, contributing heavily to mortality, disability, and long-term medical costs. Although advances in imaging, early detection, and reperfusion therapy have improved acute outcomes, there is still a striking lack of effective neuroprotective treatments. This review outlines the primary biological processes associated with ischemic injury-excitotoxicity, apoptosis, necrosis/necroptosis, altered autophagy, and post-ischemic inflammation-and describes how these mechanisms interact over time. Their interdependence affects the evolution of tissue damage and ultimately shapes recovery. A clearer understanding of how these pathways intersect may help identify new therapeutic targets. Current treatments focus almost entirely on getting blood flowing again, but they offer limited efficacy in sustaining neuronal viability or facilitating long-term functional recovery. We need a shift toward multimodal protection, immune modulation, and therapies that actually account for the specific type of clot and the patient’s own biology.
KW - Excitotoxicity;Apoptosis;Necroptosis;Autophagy;Inflammation
DO - 10.11637/aba.2026.39.1.31
ER -
정아인, Yoon-Young Chung, Hwang Hyo In, 신혜경 and YONGHYUN JUN. (2026). Understanding the Diverse Mechanisms of Stroke: Excitotoxiicty, Cell Death, and Inflammation. Anatomy & Biological Anthropology, 39(1), 31-35.
정아인, Yoon-Young Chung, Hwang Hyo In, 신혜경 and YONGHYUN JUN. 2026, "Understanding the Diverse Mechanisms of Stroke: Excitotoxiicty, Cell Death, and Inflammation", Anatomy & Biological Anthropology, vol.39, no.1 pp.31-35. Available from: doi:10.11637/aba.2026.39.1.31
정아인, Yoon-Young Chung, Hwang Hyo In, 신혜경, YONGHYUN JUN "Understanding the Diverse Mechanisms of Stroke: Excitotoxiicty, Cell Death, and Inflammation" Anatomy & Biological Anthropology 39.1 pp.31-35 (2026) : 31.
정아인, Yoon-Young Chung, Hwang Hyo In, 신혜경, YONGHYUN JUN. Understanding the Diverse Mechanisms of Stroke: Excitotoxiicty, Cell Death, and Inflammation. 2026; 39(1), 31-35. Available from: doi:10.11637/aba.2026.39.1.31
정아인, Yoon-Young Chung, Hwang Hyo In, 신혜경 and YONGHYUN JUN. "Understanding the Diverse Mechanisms of Stroke: Excitotoxiicty, Cell Death, and Inflammation" Anatomy & Biological Anthropology 39, no.1 (2026) : 31-35.doi: 10.11637/aba.2026.39.1.31
정아인; Yoon-Young Chung; Hwang Hyo In; 신혜경; YONGHYUN JUN. Understanding the Diverse Mechanisms of Stroke: Excitotoxiicty, Cell Death, and Inflammation. Anatomy & Biological Anthropology, 39(1), 31-35. doi: 10.11637/aba.2026.39.1.31
정아인; Yoon-Young Chung; Hwang Hyo In; 신혜경; YONGHYUN JUN. Understanding the Diverse Mechanisms of Stroke: Excitotoxiicty, Cell Death, and Inflammation. Anatomy & Biological Anthropology. 2026; 39(1) 31-35. doi: 10.11637/aba.2026.39.1.31
정아인, Yoon-Young Chung, Hwang Hyo In, 신혜경, YONGHYUN JUN. Understanding the Diverse Mechanisms of Stroke: Excitotoxiicty, Cell Death, and Inflammation. 2026; 39(1), 31-35. Available from: doi:10.11637/aba.2026.39.1.31
정아인, Yoon-Young Chung, Hwang Hyo In, 신혜경 and YONGHYUN JUN. "Understanding the Diverse Mechanisms of Stroke: Excitotoxiicty, Cell Death, and Inflammation" Anatomy & Biological Anthropology 39, no.1 (2026) : 31-35.doi: 10.11637/aba.2026.39.1.31
