Carbon Letters 2024 KCI Impact Factor : 0.95 KCI-WoS Impact Factor : 5.79
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pISSN : 1976-4251 / eISSN : 2233-4998
- https://journal.kci.go.kr/carbon
KJCKorea
Journal Central
Determination of the antibacterial activity of various metal-doped carbon quantum dots
- Carbon Letters
- Abbr : Carbon Lett.
- 2024, 34(8), pp.2183~2193
- DOI : 10.1007/s42823-024-00781-7
- Publisher : Korean Carbon Society
- Research Area : Natural Science > Natural Science General > Other Natural Sciences General
- Received : April 11, 2024
- Accepted : June 27, 2024
- Published : December 5, 2024
Jeong Hyojin 1, Jo Seunghyeon 1, Yang Seulah 1, Lee Songhee 1, Subramani Surendran 2, Nguyen duong nguyen 3, baeckunbeom 3, Jung Kyu Kim 3, Uk Sim 4, Shin Sooim 1
1전남대학교
2Korea Institute of Energy Technology
3성균관대학교
4Research Institute, NEEL Sciences, INC., Naju, Republic of Korea
Accredited
ABSTRACT
Carbon quantum dots (CQDs) are novel nanocarbon materials and widely used nanoparticles. They have gradually gained popularity in various fields due to their abundance, inexpensive cost, small size, ease of engineering, and distinct properties. To determine the antibacterial activity of metal-doped CQDs (metal-CQDs) containing Fe, Zn, Mn, Ni, and Co, we chose Staphylococcus aureus as a representative Gram-positive strain and Escherichia coli as a representative Gram-negative bacterial strain. Paper disc diffusion tests were conducted for the qualitative results, and a cell growth curve was drawn for quantitative results. The minimum inhibitory concentration (MIC), minimum bactericidal concentration (MBC), and IC50 were measured from cell growth curves. As a result, all of the metal-CQDs showed toxicity against both Gram-positive and Gram-negative bacteria. Furthermore, Gram-negative bacteria was vulnerable to metal-CQDs than Gram-positive bacteria. The toxicity differed concerning the type of metal-CQDs; Mn-CQDs exhibited the highest efficacy. Hence, this study suggested that CQDs can be used as new nanoparticles for antibiotics.
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This paper was written with support from the National Research Foundation of Korea.