@article{ART003208919},
author={Dhamodharan A. and Murugan E. and Pang Huan and Perumal K. and Jhansirani K. and Gao Yajun},
title={Facile fabrication of CdS@GO binary nanocomposite coated GCE for separate and parallel electrochemical sensing of ascorbic acid, uric acid and nitrite},
journal={Carbon Letters},
issn={1976-4251},
year={2025},
volume={35},
number={2},
pages={881-893},
doi={10.1007/s42823-024-00838-7}
TY - JOUR
AU - Dhamodharan A.
AU - Murugan E.
AU - Pang Huan
AU - Perumal K.
AU - Jhansirani K.
AU - Gao Yajun
TI - Facile fabrication of CdS@GO binary nanocomposite coated GCE for separate and parallel electrochemical sensing of ascorbic acid, uric acid and nitrite
JO - Carbon Letters
PY - 2025
VL - 35
IS - 2
PB - Korean Carbon Society
SP - 881
EP - 893
SN - 1976-4251
AB - The accurate detection of vital biomarkers such as Ascorbic Acid (AA), Uric Acid (UA) and Nitrite (NO2−) is crucial for human health surveillance. However, existing methods often struggle with concurrent detection and quantification of multiple species, highlighting the need for a more effective solution. To address this challenge, this study aimed to develop a multifunctional electrochemical sensor capable of parallel detection of AA, UA and NO2− using a synergistic combination of Graphene Oxide (GO) and Cadmium Sulfide (CdS) materials. Notably, the fabricated CdS@GO/Glassy Carbon Electrode (GCE) exhibited exceptional electrochemical activity, as evidenced by Differential Pulse Voltammetry (DPV) analysis. The sensor demonstrated remarkable sensitivity (8.13, 10.12, and 9.05 μA·μM−1·cm−2) and ultra-low detection limits (0.034, 0.062, and 0.084 µM) for AA, UA and NO2−, respectively. Furthermore, it successfully identified single molecules of each analyte in aqueous and biologic fluid samples, with recovery values comparable to those obtained using High-Performance Liquid Chromatography (HPLC) standard addition methods. The significance of this study lies in developing a novel CdS@GO/GCE sensor that enables concurrent detection and quantification of multiple vital biomarkers, offering a promising tool for human health monitoring and diagnosis.
KW - Graphene Oxide Cadmium Sulfide Voltammetry Uric Acid Nitrite Simultaneous sensing
DO - 10.1007/s42823-024-00838-7
ER -
Dhamodharan A., Murugan E., Pang Huan, Perumal K., Jhansirani K. and Gao Yajun. (2025). Facile fabrication of CdS@GO binary nanocomposite coated GCE for separate and parallel electrochemical sensing of ascorbic acid, uric acid and nitrite. Carbon Letters, 35(2), 881-893.
Dhamodharan A., Murugan E., Pang Huan, Perumal K., Jhansirani K. and Gao Yajun. 2025, "Facile fabrication of CdS@GO binary nanocomposite coated GCE for separate and parallel electrochemical sensing of ascorbic acid, uric acid and nitrite", Carbon Letters, vol.35, no.2 pp.881-893. Available from: doi:10.1007/s42823-024-00838-7
Dhamodharan A., Murugan E., Pang Huan, Perumal K., Jhansirani K., Gao Yajun "Facile fabrication of CdS@GO binary nanocomposite coated GCE for separate and parallel electrochemical sensing of ascorbic acid, uric acid and nitrite" Carbon Letters 35.2 pp.881-893 (2025) : 881.
Dhamodharan A., Murugan E., Pang Huan, Perumal K., Jhansirani K., Gao Yajun. Facile fabrication of CdS@GO binary nanocomposite coated GCE for separate and parallel electrochemical sensing of ascorbic acid, uric acid and nitrite. 2025; 35(2), 881-893. Available from: doi:10.1007/s42823-024-00838-7
Dhamodharan A., Murugan E., Pang Huan, Perumal K., Jhansirani K. and Gao Yajun. "Facile fabrication of CdS@GO binary nanocomposite coated GCE for separate and parallel electrochemical sensing of ascorbic acid, uric acid and nitrite" Carbon Letters 35, no.2 (2025) : 881-893.doi: 10.1007/s42823-024-00838-7
Dhamodharan A.; Murugan E.; Pang Huan; Perumal K.; Jhansirani K.; Gao Yajun. Facile fabrication of CdS@GO binary nanocomposite coated GCE for separate and parallel electrochemical sensing of ascorbic acid, uric acid and nitrite. Carbon Letters, 35(2), 881-893. doi: 10.1007/s42823-024-00838-7
Dhamodharan A.; Murugan E.; Pang Huan; Perumal K.; Jhansirani K.; Gao Yajun. Facile fabrication of CdS@GO binary nanocomposite coated GCE for separate and parallel electrochemical sensing of ascorbic acid, uric acid and nitrite. Carbon Letters. 2025; 35(2) 881-893. doi: 10.1007/s42823-024-00838-7
Dhamodharan A., Murugan E., Pang Huan, Perumal K., Jhansirani K., Gao Yajun. Facile fabrication of CdS@GO binary nanocomposite coated GCE for separate and parallel electrochemical sensing of ascorbic acid, uric acid and nitrite. 2025; 35(2), 881-893. Available from: doi:10.1007/s42823-024-00838-7
Dhamodharan A., Murugan E., Pang Huan, Perumal K., Jhansirani K. and Gao Yajun. "Facile fabrication of CdS@GO binary nanocomposite coated GCE for separate and parallel electrochemical sensing of ascorbic acid, uric acid and nitrite" Carbon Letters 35, no.2 (2025) : 881-893.doi: 10.1007/s42823-024-00838-7
