@article{ART003208919},
author={A. Dhamodharan and E. Murugan and Huan Pang and K. Perumal and K. Jhansirani and Yajun Gao},
title={Facile fabrication of CdS@GO binary nanocomposite coated GCE for separate and parallel electrochemical sensing of ascorbic acid, uric acid and nitrite},
journal={Carbon Letters},
issn={1976-4251},
year={2025},
volume={35},
number={2},
pages={881-893},
doi={10.1007/s42823-024-00838-7}
TY - JOUR
AU - A. Dhamodharan
AU - E. Murugan
AU - Huan Pang
AU - K. Perumal
AU - K. Jhansirani
AU - Yajun Gao
TI - Facile fabrication of CdS@GO binary nanocomposite coated GCE for separate and parallel electrochemical sensing of ascorbic acid, uric acid and nitrite
JO - Carbon Letters
PY - 2025
VL - 35
IS - 2
PB - Korean Carbon Society
SP - 881
EP - 893
SN - 1976-4251
AB - The accurate detection of vital biomarkers such as Ascorbic Acid (AA), Uric Acid (UA) and Nitrite (NO2−) is crucial for human health surveillance. However, existing methods often struggle with concurrent detection and quantification of multiple species, highlighting the need for a more effective solution. To address this challenge, this study aimed to develop a multifunctional electrochemical sensor capable of parallel detection of AA, UA and NO2− using a synergistic combination of Graphene Oxide (GO) and Cadmium Sulfide (CdS) materials. Notably, the fabricated CdS@GO/Glassy Carbon Electrode (GCE) exhibited exceptional electrochemical activity, as evidenced by Differential Pulse Voltammetry (DPV) analysis. The sensor demonstrated remarkable sensitivity (8.13, 10.12, and 9.05 μA·μM−1·cm−2) and ultra-low detection limits (0.034, 0.062, and 0.084 µM) for AA, UA and NO2−, respectively. Furthermore, it successfully identified single molecules of each analyte in aqueous and biologic fluid samples, with recovery values comparable to those obtained using High-Performance Liquid Chromatography (HPLC) standard addition methods. The significance of this study lies in developing a novel CdS@GO/GCE sensor that enables concurrent detection and quantification of multiple vital biomarkers, offering a promising tool for human health monitoring and diagnosis.
KW - Graphene Oxide;Cadmium Sulfide;Voltammetry;Uric Acid;Nitrite;Simultaneous sensing
DO - 10.1007/s42823-024-00838-7
ER -
A. Dhamodharan, E. Murugan, Huan Pang, K. Perumal, K. Jhansirani and Yajun Gao. (2025). Facile fabrication of CdS@GO binary nanocomposite coated GCE for separate and parallel electrochemical sensing of ascorbic acid, uric acid and nitrite. Carbon Letters, 35(2), 881-893.
A. Dhamodharan, E. Murugan, Huan Pang, K. Perumal, K. Jhansirani and Yajun Gao. 2025, "Facile fabrication of CdS@GO binary nanocomposite coated GCE for separate and parallel electrochemical sensing of ascorbic acid, uric acid and nitrite", Carbon Letters, vol.35, no.2 pp.881-893. Available from: doi:10.1007/s42823-024-00838-7
A. Dhamodharan, E. Murugan, Huan Pang, K. Perumal, K. Jhansirani, Yajun Gao "Facile fabrication of CdS@GO binary nanocomposite coated GCE for separate and parallel electrochemical sensing of ascorbic acid, uric acid and nitrite" Carbon Letters 35.2 pp.881-893 (2025) : 881.
A. Dhamodharan, E. Murugan, Huan Pang, K. Perumal, K. Jhansirani, Yajun Gao. Facile fabrication of CdS@GO binary nanocomposite coated GCE for separate and parallel electrochemical sensing of ascorbic acid, uric acid and nitrite. 2025; 35(2), 881-893. Available from: doi:10.1007/s42823-024-00838-7
A. Dhamodharan, E. Murugan, Huan Pang, K. Perumal, K. Jhansirani and Yajun Gao. "Facile fabrication of CdS@GO binary nanocomposite coated GCE for separate and parallel electrochemical sensing of ascorbic acid, uric acid and nitrite" Carbon Letters 35, no.2 (2025) : 881-893.doi: 10.1007/s42823-024-00838-7
A. Dhamodharan; E. Murugan; Huan Pang; K. Perumal; K. Jhansirani; Yajun Gao. Facile fabrication of CdS@GO binary nanocomposite coated GCE for separate and parallel electrochemical sensing of ascorbic acid, uric acid and nitrite. Carbon Letters, 35(2), 881-893. doi: 10.1007/s42823-024-00838-7
A. Dhamodharan; E. Murugan; Huan Pang; K. Perumal; K. Jhansirani; Yajun Gao. Facile fabrication of CdS@GO binary nanocomposite coated GCE for separate and parallel electrochemical sensing of ascorbic acid, uric acid and nitrite. Carbon Letters. 2025; 35(2) 881-893. doi: 10.1007/s42823-024-00838-7
A. Dhamodharan, E. Murugan, Huan Pang, K. Perumal, K. Jhansirani, Yajun Gao. Facile fabrication of CdS@GO binary nanocomposite coated GCE for separate and parallel electrochemical sensing of ascorbic acid, uric acid and nitrite. 2025; 35(2), 881-893. Available from: doi:10.1007/s42823-024-00838-7
A. Dhamodharan, E. Murugan, Huan Pang, K. Perumal, K. Jhansirani and Yajun Gao. "Facile fabrication of CdS@GO binary nanocomposite coated GCE for separate and parallel electrochemical sensing of ascorbic acid, uric acid and nitrite" Carbon Letters 35, no.2 (2025) : 881-893.doi: 10.1007/s42823-024-00838-7
