@article{ART003241561},
author={Ding Lixin and Sun Na and Zuo He and Luan Fang and Hou Lin and Chen Zhiyou and Sun Xue and Zheng Yuting and Dai Zongyu and Lv Yuguang and Hou Xingyu},
title={Green one-step synthesis of carbon dots via waste grape seeds as fluorescent probe for detection of folic acid in biological samples},
journal={Carbon Letters},
issn={1976-4251},
year={2025},
volume={35},
number={3},
pages={1397-1406},
doi={10.1007/s42823-025-00875-w}
TY - JOUR
AU - Ding Lixin
AU - Sun Na
AU - Zuo He
AU - Luan Fang
AU - Hou Lin
AU - Chen Zhiyou
AU - Sun Xue
AU - Zheng Yuting
AU - Dai Zongyu
AU - Lv Yuguang
AU - Hou Xingyu
TI - Green one-step synthesis of carbon dots via waste grape seeds as fluorescent probe for detection of folic acid in biological samples
JO - Carbon Letters
PY - 2025
VL - 35
IS - 3
PB - Korean Carbon Society
SP - 1397
EP - 1406
SN - 1976-4251
AB - Waste utilization is not only a way to protect the environment and realize green chemistry, but also a means to create novel materials. In this study, based on waste grape seeds as the biowaste-derived carbon dots (G-BCDs), a straightforward one-pot green method was employed for the rapid detection of folic acid (FA). Owing to the internal filter effect and the static mixing quenching mechanism, the sensing principle of G-BCDs was effectively quenched by FA. The results showed fluorescence at an emission wavelength of 415 nm upon excitation at 330 nm with a quantum yield of 1.5%. Particularly, the FA sensing assay obtained a broad linear range of 2–220 μM and the limit of detection was 0.48 μM. In addition, the fluorescence probe was successfully utilized for detecting FA in tablets, blood, and urine samples, yielding desirable results, which indicated promising applications in the fields of biological and pharmaceutical analysis.
KW - Biowaste-derived carbon dots;Green synthesis;Folic acid;Static quenching;Internal filter effect
DO - 10.1007/s42823-025-00875-w
ER -
Ding Lixin, Sun Na, Zuo He, Luan Fang, Hou Lin, Chen Zhiyou, Sun Xue, Zheng Yuting, Dai Zongyu, Lv Yuguang and Hou Xingyu. (2025). Green one-step synthesis of carbon dots via waste grape seeds as fluorescent probe for detection of folic acid in biological samples. Carbon Letters, 35(3), 1397-1406.
Ding Lixin, Sun Na, Zuo He, Luan Fang, Hou Lin, Chen Zhiyou, Sun Xue, Zheng Yuting, Dai Zongyu, Lv Yuguang and Hou Xingyu. 2025, "Green one-step synthesis of carbon dots via waste grape seeds as fluorescent probe for detection of folic acid in biological samples", Carbon Letters, vol.35, no.3 pp.1397-1406. Available from: doi:10.1007/s42823-025-00875-w
Ding Lixin, Sun Na, Zuo He, Luan Fang, Hou Lin, Chen Zhiyou, Sun Xue, Zheng Yuting, Dai Zongyu, Lv Yuguang, Hou Xingyu "Green one-step synthesis of carbon dots via waste grape seeds as fluorescent probe for detection of folic acid in biological samples" Carbon Letters 35.3 pp.1397-1406 (2025) : 1397.
Ding Lixin, Sun Na, Zuo He, Luan Fang, Hou Lin, Chen Zhiyou, Sun Xue, Zheng Yuting, Dai Zongyu, Lv Yuguang, Hou Xingyu. Green one-step synthesis of carbon dots via waste grape seeds as fluorescent probe for detection of folic acid in biological samples. 2025; 35(3), 1397-1406. Available from: doi:10.1007/s42823-025-00875-w
Ding Lixin, Sun Na, Zuo He, Luan Fang, Hou Lin, Chen Zhiyou, Sun Xue, Zheng Yuting, Dai Zongyu, Lv Yuguang and Hou Xingyu. "Green one-step synthesis of carbon dots via waste grape seeds as fluorescent probe for detection of folic acid in biological samples" Carbon Letters 35, no.3 (2025) : 1397-1406.doi: 10.1007/s42823-025-00875-w
Ding Lixin; Sun Na; Zuo He; Luan Fang; Hou Lin; Chen Zhiyou; Sun Xue; Zheng Yuting; Dai Zongyu; Lv Yuguang; Hou Xingyu. Green one-step synthesis of carbon dots via waste grape seeds as fluorescent probe for detection of folic acid in biological samples. Carbon Letters, 35(3), 1397-1406. doi: 10.1007/s42823-025-00875-w
Ding Lixin; Sun Na; Zuo He; Luan Fang; Hou Lin; Chen Zhiyou; Sun Xue; Zheng Yuting; Dai Zongyu; Lv Yuguang; Hou Xingyu. Green one-step synthesis of carbon dots via waste grape seeds as fluorescent probe for detection of folic acid in biological samples. Carbon Letters. 2025; 35(3) 1397-1406. doi: 10.1007/s42823-025-00875-w
Ding Lixin, Sun Na, Zuo He, Luan Fang, Hou Lin, Chen Zhiyou, Sun Xue, Zheng Yuting, Dai Zongyu, Lv Yuguang, Hou Xingyu. Green one-step synthesis of carbon dots via waste grape seeds as fluorescent probe for detection of folic acid in biological samples. 2025; 35(3), 1397-1406. Available from: doi:10.1007/s42823-025-00875-w
Ding Lixin, Sun Na, Zuo He, Luan Fang, Hou Lin, Chen Zhiyou, Sun Xue, Zheng Yuting, Dai Zongyu, Lv Yuguang and Hou Xingyu. "Green one-step synthesis of carbon dots via waste grape seeds as fluorescent probe for detection of folic acid in biological samples" Carbon Letters 35, no.3 (2025) : 1397-1406.doi: 10.1007/s42823-025-00875-w
