@article{ART003241561},
author={Lixin Ding and Na Sun and He Zuo and Fang Luan and Lin Hou and Zhiyou Chen and Xue Sun and Yuting Zheng and Zongyu Dai and Yuguang Lv and Xingyu Hou},
title={Green one-step synthesis of carbon dots via waste grape seeds as fluorescent probe for detection of folic acid in biological samples},
journal={Carbon Letters},
issn={1976-4251},
year={2025},
volume={35},
number={3},
pages={1397-1406},
doi={10.1007/s42823-025-00875-w}
TY - JOUR
AU - Lixin Ding
AU - Na Sun
AU - He Zuo
AU - Fang Luan
AU - Lin Hou
AU - Zhiyou Chen
AU - Xue Sun
AU - Yuting Zheng
AU - Zongyu Dai
AU - Yuguang Lv
AU - Xingyu Hou
TI - Green one-step synthesis of carbon dots via waste grape seeds as fluorescent probe for detection of folic acid in biological samples
JO - Carbon Letters
PY - 2025
VL - 35
IS - 3
PB - Korean Carbon Society
SP - 1397
EP - 1406
SN - 1976-4251
AB - Waste utilization is not only a way to protect the environment and realize green chemistry, but also a means to create novel materials. In this study, based on waste grape seeds as the biowaste-derived carbon dots (G-BCDs), a straightforward one-pot green method was employed for the rapid detection of folic acid (FA). Owing to the internal filter effect and the static mixing quenching mechanism, the sensing principle of G-BCDs was effectively quenched by FA. The results showed fluorescence at an emission wavelength of 415 nm upon excitation at 330 nm with a quantum yield of 1.5%. Particularly, the FA sensing assay obtained a broad linear range of 2–220 μM and the limit of detection was 0.48 μM. In addition, the fluorescence probe was successfully utilized for detecting FA in tablets, blood, and urine samples, yielding desirable results, which indicated promising applications in the fields of biological and pharmaceutical analysis.
KW - Biowaste-derived carbon dots;Green synthesis;Folic acid;Static quenching;Internal filter effect
DO - 10.1007/s42823-025-00875-w
ER -
Lixin Ding, Na Sun, He Zuo, Fang Luan, Lin Hou, Zhiyou Chen, Xue Sun, Yuting Zheng, Zongyu Dai, Yuguang Lv and Xingyu Hou. (2025). Green one-step synthesis of carbon dots via waste grape seeds as fluorescent probe for detection of folic acid in biological samples. Carbon Letters, 35(3), 1397-1406.
Lixin Ding, Na Sun, He Zuo, Fang Luan, Lin Hou, Zhiyou Chen, Xue Sun, Yuting Zheng, Zongyu Dai, Yuguang Lv and Xingyu Hou. 2025, "Green one-step synthesis of carbon dots via waste grape seeds as fluorescent probe for detection of folic acid in biological samples", Carbon Letters, vol.35, no.3 pp.1397-1406. Available from: doi:10.1007/s42823-025-00875-w
Lixin Ding, Na Sun, He Zuo, Fang Luan, Lin Hou, Zhiyou Chen, Xue Sun, Yuting Zheng, Zongyu Dai, Yuguang Lv, Xingyu Hou "Green one-step synthesis of carbon dots via waste grape seeds as fluorescent probe for detection of folic acid in biological samples" Carbon Letters 35.3 pp.1397-1406 (2025) : 1397.
Lixin Ding, Na Sun, He Zuo, Fang Luan, Lin Hou, Zhiyou Chen, Xue Sun, Yuting Zheng, Zongyu Dai, Yuguang Lv, Xingyu Hou. Green one-step synthesis of carbon dots via waste grape seeds as fluorescent probe for detection of folic acid in biological samples. 2025; 35(3), 1397-1406. Available from: doi:10.1007/s42823-025-00875-w
Lixin Ding, Na Sun, He Zuo, Fang Luan, Lin Hou, Zhiyou Chen, Xue Sun, Yuting Zheng, Zongyu Dai, Yuguang Lv and Xingyu Hou. "Green one-step synthesis of carbon dots via waste grape seeds as fluorescent probe for detection of folic acid in biological samples" Carbon Letters 35, no.3 (2025) : 1397-1406.doi: 10.1007/s42823-025-00875-w
Lixin Ding; Na Sun; He Zuo; Fang Luan; Lin Hou; Zhiyou Chen; Xue Sun; Yuting Zheng; Zongyu Dai; Yuguang Lv; Xingyu Hou. Green one-step synthesis of carbon dots via waste grape seeds as fluorescent probe for detection of folic acid in biological samples. Carbon Letters, 35(3), 1397-1406. doi: 10.1007/s42823-025-00875-w
Lixin Ding; Na Sun; He Zuo; Fang Luan; Lin Hou; Zhiyou Chen; Xue Sun; Yuting Zheng; Zongyu Dai; Yuguang Lv; Xingyu Hou. Green one-step synthesis of carbon dots via waste grape seeds as fluorescent probe for detection of folic acid in biological samples. Carbon Letters. 2025; 35(3) 1397-1406. doi: 10.1007/s42823-025-00875-w
Lixin Ding, Na Sun, He Zuo, Fang Luan, Lin Hou, Zhiyou Chen, Xue Sun, Yuting Zheng, Zongyu Dai, Yuguang Lv, Xingyu Hou. Green one-step synthesis of carbon dots via waste grape seeds as fluorescent probe for detection of folic acid in biological samples. 2025; 35(3), 1397-1406. Available from: doi:10.1007/s42823-025-00875-w
Lixin Ding, Na Sun, He Zuo, Fang Luan, Lin Hou, Zhiyou Chen, Xue Sun, Yuting Zheng, Zongyu Dai, Yuguang Lv and Xingyu Hou. "Green one-step synthesis of carbon dots via waste grape seeds as fluorescent probe for detection of folic acid in biological samples" Carbon Letters 35, no.3 (2025) : 1397-1406.doi: 10.1007/s42823-025-00875-w
