@article{ART003273036},
author={Alvandi Hale and Shafie Anahid and Najafi Fatemeh and Sabzini Mahdi and Mashayekhi Mohammad and Omami Sahand Hedayati and Eskandarisani Mohammad Mahdi and Dashti Shamim and Javanmard Alireza and Tajik Mohammadreza and Bräse Stefan and Farmani Ahmad Reza},
title={Carbon-based nanostructure drug delivery systems and their biologic applications – a review},
journal={Carbon Letters},
issn={1976-4251},
year={2025},
volume={35},
number={4},
pages={1529-1587},
doi={10.1007/s42823-025-00927-1}
TY - JOUR
AU - Alvandi Hale
AU - Shafie Anahid
AU - Najafi Fatemeh
AU - Sabzini Mahdi
AU - Mashayekhi Mohammad
AU - Omami Sahand Hedayati
AU - Eskandarisani Mohammad Mahdi
AU - Dashti Shamim
AU - Javanmard Alireza
AU - Tajik Mohammadreza
AU - Bräse Stefan
AU - Farmani Ahmad Reza
TI - Carbon-based nanostructure drug delivery systems and their biologic applications – a review
JO - Carbon Letters
PY - 2025
VL - 35
IS - 4
PB - Korean Carbon Society
SP - 1529
EP - 1587
SN - 1976-4251
AB - Presently, the majority of cancer treatments are non-specific, leading to undesirable side effects from intense medications. This issue may be addressed through the revolutionary advancement of nanotechnology, which enables the control of materials at the nanoscale. By offering advantages such as customized drug delivery, minimized dose-associated side effects, and extended drug circulation times, nanotechnology has significantly impacted cancer therapy over recent decades. Due to their unique combination of superior optical, thermal, electrical, and mechanical properties, carbon-based nanoparticles are emerging as promising tools in cancer research. These nanoparticles also offer ease of modification and a large surface area, making them ideal for efficient drug delivery. These nanoplatforms can serve as carriers for multiple types of molecules, enabling targeted and controlled delivery of pharmaceuticals, nucleotides, and diagnostic agents. The synthesis techniques and functionalization approaches of carbon-based nanostructures, both covalently and noncovalently bound, will be explored in detail within this review. In addition, the properties of carbon nanostructures, their potential for delivering anticancer drugs and genetic material, as well as their antibacterial capabilities, will be analyzed. Lastly, the challenges associated with utilizing carbon nanostructures and future perspectives will be discussed.
KW - Carbon-based nanostructures;Functionalization;Anticancer activity;Antibacterial activity;Gene delivery
DO - 10.1007/s42823-025-00927-1
ER -
Alvandi Hale, Shafie Anahid, Najafi Fatemeh, Sabzini Mahdi, Mashayekhi Mohammad, Omami Sahand Hedayati, Eskandarisani Mohammad Mahdi, Dashti Shamim, Javanmard Alireza, Tajik Mohammadreza, Bräse Stefan and Farmani Ahmad Reza. (2025). Carbon-based nanostructure drug delivery systems and their biologic applications – a review. Carbon Letters, 35(4), 1529-1587.
Alvandi Hale, Shafie Anahid, Najafi Fatemeh, Sabzini Mahdi, Mashayekhi Mohammad, Omami Sahand Hedayati, Eskandarisani Mohammad Mahdi, Dashti Shamim, Javanmard Alireza, Tajik Mohammadreza, Bräse Stefan and Farmani Ahmad Reza. 2025, "Carbon-based nanostructure drug delivery systems and their biologic applications – a review", Carbon Letters, vol.35, no.4 pp.1529-1587. Available from: doi:10.1007/s42823-025-00927-1
Alvandi Hale, Shafie Anahid, Najafi Fatemeh, Sabzini Mahdi, Mashayekhi Mohammad, Omami Sahand Hedayati, Eskandarisani Mohammad Mahdi, Dashti Shamim, Javanmard Alireza, Tajik Mohammadreza, Bräse Stefan, Farmani Ahmad Reza "Carbon-based nanostructure drug delivery systems and their biologic applications – a review" Carbon Letters 35.4 pp.1529-1587 (2025) : 1529.
Alvandi Hale, Shafie Anahid, Najafi Fatemeh, Sabzini Mahdi, Mashayekhi Mohammad, Omami Sahand Hedayati, Eskandarisani Mohammad Mahdi, Dashti Shamim, Javanmard Alireza, Tajik Mohammadreza, Bräse Stefan, Farmani Ahmad Reza. Carbon-based nanostructure drug delivery systems and their biologic applications – a review. 2025; 35(4), 1529-1587. Available from: doi:10.1007/s42823-025-00927-1
Alvandi Hale, Shafie Anahid, Najafi Fatemeh, Sabzini Mahdi, Mashayekhi Mohammad, Omami Sahand Hedayati, Eskandarisani Mohammad Mahdi, Dashti Shamim, Javanmard Alireza, Tajik Mohammadreza, Bräse Stefan and Farmani Ahmad Reza. "Carbon-based nanostructure drug delivery systems and their biologic applications – a review" Carbon Letters 35, no.4 (2025) : 1529-1587.doi: 10.1007/s42823-025-00927-1
Alvandi Hale; Shafie Anahid; Najafi Fatemeh; Sabzini Mahdi; Mashayekhi Mohammad; Omami Sahand Hedayati; Eskandarisani Mohammad Mahdi; Dashti Shamim; Javanmard Alireza; Tajik Mohammadreza; Bräse Stefan; Farmani Ahmad Reza. Carbon-based nanostructure drug delivery systems and their biologic applications – a review. Carbon Letters, 35(4), 1529-1587. doi: 10.1007/s42823-025-00927-1
Alvandi Hale; Shafie Anahid; Najafi Fatemeh; Sabzini Mahdi; Mashayekhi Mohammad; Omami Sahand Hedayati; Eskandarisani Mohammad Mahdi; Dashti Shamim; Javanmard Alireza; Tajik Mohammadreza; Bräse Stefan; Farmani Ahmad Reza. Carbon-based nanostructure drug delivery systems and their biologic applications – a review. Carbon Letters. 2025; 35(4) 1529-1587. doi: 10.1007/s42823-025-00927-1
Alvandi Hale, Shafie Anahid, Najafi Fatemeh, Sabzini Mahdi, Mashayekhi Mohammad, Omami Sahand Hedayati, Eskandarisani Mohammad Mahdi, Dashti Shamim, Javanmard Alireza, Tajik Mohammadreza, Bräse Stefan, Farmani Ahmad Reza. Carbon-based nanostructure drug delivery systems and their biologic applications – a review. 2025; 35(4), 1529-1587. Available from: doi:10.1007/s42823-025-00927-1
Alvandi Hale, Shafie Anahid, Najafi Fatemeh, Sabzini Mahdi, Mashayekhi Mohammad, Omami Sahand Hedayati, Eskandarisani Mohammad Mahdi, Dashti Shamim, Javanmard Alireza, Tajik Mohammadreza, Bräse Stefan and Farmani Ahmad Reza. "Carbon-based nanostructure drug delivery systems and their biologic applications – a review" Carbon Letters 35, no.4 (2025) : 1529-1587.doi: 10.1007/s42823-025-00927-1
