@article{ART003273036},
author={Hale Alvandi and Anahid Shafie and Fatemeh Najafi and Mahdi Sabzini and Mohammad Mashayekhi and Sahand Hedayati Omami and Mohammad Mahdi Eskandarisani and Shamim Dashti and Alireza Javanmard and Mohammadreza Tajik and Stefan Bräse and Ahmad Reza Farmani},
title={Carbon-based nanostructure drug delivery systems and their biologic applications – a review},
journal={Carbon Letters},
issn={1976-4251},
year={2025},
volume={35},
number={4},
pages={1529-1587},
doi={10.1007/s42823-025-00927-1}
TY - JOUR
AU - Hale Alvandi
AU - Anahid Shafie
AU - Fatemeh Najafi
AU - Mahdi Sabzini
AU - Mohammad Mashayekhi
AU - Sahand Hedayati Omami
AU - Mohammad Mahdi Eskandarisani
AU - Shamim Dashti
AU - Alireza Javanmard
AU - Mohammadreza Tajik
AU - Stefan Bräse
AU - Ahmad Reza Farmani
TI - Carbon-based nanostructure drug delivery systems and their biologic applications – a review
JO - Carbon Letters
PY - 2025
VL - 35
IS - 4
PB - Korean Carbon Society
SP - 1529
EP - 1587
SN - 1976-4251
AB - Presently, the majority of cancer treatments are non-specific, leading to undesirable side effects from intense medications. This issue may be addressed through the revolutionary advancement of nanotechnology, which enables the control of materials at the nanoscale. By offering advantages such as customized drug delivery, minimized dose-associated side effects, and extended drug circulation times, nanotechnology has significantly impacted cancer therapy over recent decades. Due to their unique combination of superior optical, thermal, electrical, and mechanical properties, carbon-based nanoparticles are emerging as promising tools in cancer research. These nanoparticles also offer ease of modification and a large surface area, making them ideal for efficient drug delivery. These nanoplatforms can serve as carriers for multiple types of molecules, enabling targeted and controlled delivery of pharmaceuticals, nucleotides, and diagnostic agents. The synthesis techniques and functionalization approaches of carbon-based nanostructures, both covalently and noncovalently bound, will be explored in detail within this review. In addition, the properties of carbon nanostructures, their potential for delivering anticancer drugs and genetic material, as well as their antibacterial capabilities, will be analyzed. Lastly, the challenges associated with utilizing carbon nanostructures and future perspectives will be discussed.
KW - Carbon-based nanostructures;Functionalization;Anticancer activity;Antibacterial activity;Gene delivery
DO - 10.1007/s42823-025-00927-1
ER -
Hale Alvandi, Anahid Shafie, Fatemeh Najafi, Mahdi Sabzini, Mohammad Mashayekhi, Sahand Hedayati Omami, Mohammad Mahdi Eskandarisani, Shamim Dashti, Alireza Javanmard, Mohammadreza Tajik, Stefan Bräse and Ahmad Reza Farmani. (2025). Carbon-based nanostructure drug delivery systems and their biologic applications – a review. Carbon Letters, 35(4), 1529-1587.
Hale Alvandi, Anahid Shafie, Fatemeh Najafi, Mahdi Sabzini, Mohammad Mashayekhi, Sahand Hedayati Omami, Mohammad Mahdi Eskandarisani, Shamim Dashti, Alireza Javanmard, Mohammadreza Tajik, Stefan Bräse and Ahmad Reza Farmani. 2025, "Carbon-based nanostructure drug delivery systems and their biologic applications – a review", Carbon Letters, vol.35, no.4 pp.1529-1587. Available from: doi:10.1007/s42823-025-00927-1
Hale Alvandi, Anahid Shafie, Fatemeh Najafi, Mahdi Sabzini, Mohammad Mashayekhi, Sahand Hedayati Omami, Mohammad Mahdi Eskandarisani, Shamim Dashti, Alireza Javanmard, Mohammadreza Tajik, Stefan Bräse, Ahmad Reza Farmani "Carbon-based nanostructure drug delivery systems and their biologic applications – a review" Carbon Letters 35.4 pp.1529-1587 (2025) : 1529.
Hale Alvandi, Anahid Shafie, Fatemeh Najafi, Mahdi Sabzini, Mohammad Mashayekhi, Sahand Hedayati Omami, Mohammad Mahdi Eskandarisani, Shamim Dashti, Alireza Javanmard, Mohammadreza Tajik, Stefan Bräse, Ahmad Reza Farmani. Carbon-based nanostructure drug delivery systems and their biologic applications – a review. 2025; 35(4), 1529-1587. Available from: doi:10.1007/s42823-025-00927-1
Hale Alvandi, Anahid Shafie, Fatemeh Najafi, Mahdi Sabzini, Mohammad Mashayekhi, Sahand Hedayati Omami, Mohammad Mahdi Eskandarisani, Shamim Dashti, Alireza Javanmard, Mohammadreza Tajik, Stefan Bräse and Ahmad Reza Farmani. "Carbon-based nanostructure drug delivery systems and their biologic applications – a review" Carbon Letters 35, no.4 (2025) : 1529-1587.doi: 10.1007/s42823-025-00927-1
Hale Alvandi; Anahid Shafie; Fatemeh Najafi; Mahdi Sabzini; Mohammad Mashayekhi; Sahand Hedayati Omami; Mohammad Mahdi Eskandarisani; Shamim Dashti; Alireza Javanmard; Mohammadreza Tajik; Stefan Bräse; Ahmad Reza Farmani. Carbon-based nanostructure drug delivery systems and their biologic applications – a review. Carbon Letters, 35(4), 1529-1587. doi: 10.1007/s42823-025-00927-1
Hale Alvandi; Anahid Shafie; Fatemeh Najafi; Mahdi Sabzini; Mohammad Mashayekhi; Sahand Hedayati Omami; Mohammad Mahdi Eskandarisani; Shamim Dashti; Alireza Javanmard; Mohammadreza Tajik; Stefan Bräse; Ahmad Reza Farmani. Carbon-based nanostructure drug delivery systems and their biologic applications – a review. Carbon Letters. 2025; 35(4) 1529-1587. doi: 10.1007/s42823-025-00927-1
Hale Alvandi, Anahid Shafie, Fatemeh Najafi, Mahdi Sabzini, Mohammad Mashayekhi, Sahand Hedayati Omami, Mohammad Mahdi Eskandarisani, Shamim Dashti, Alireza Javanmard, Mohammadreza Tajik, Stefan Bräse, Ahmad Reza Farmani. Carbon-based nanostructure drug delivery systems and their biologic applications – a review. 2025; 35(4), 1529-1587. Available from: doi:10.1007/s42823-025-00927-1
Hale Alvandi, Anahid Shafie, Fatemeh Najafi, Mahdi Sabzini, Mohammad Mashayekhi, Sahand Hedayati Omami, Mohammad Mahdi Eskandarisani, Shamim Dashti, Alireza Javanmard, Mohammadreza Tajik, Stefan Bräse and Ahmad Reza Farmani. "Carbon-based nanostructure drug delivery systems and their biologic applications – a review" Carbon Letters 35, no.4 (2025) : 1529-1587.doi: 10.1007/s42823-025-00927-1
