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The regulatory effect of AST cream on atopic dermatitis-like skin disease.

  • CELLMED
  • Abbr : CellMed
  • 2019, 9(3), pp.7-7
  • Publisher : Cellmed Orthocellular Medicine and Pharmaceutical Association
  • Research Area : Medicine and Pharmacy > General Medicine
  • Published : August 31, 2019

Hyun-Ja Jeong 1 Hyung-Min Kim 2 nara Han 2

1호서대학교
2경희대학교

Candidate

ABSTRACT

In this study, we investigated an inhibitory effect of AST cream on atopic dermatitis (AD) using a 2,4-dinitrochlorobenzene-induced AD murine model. Topical treatment with AST cream ameliorated the severity of AD-like lesional skin through decreases in infiltration of inflammatory cells and time of scratching behaviors. Also, AST cream reduced histamine and IgE levels in serum. The protein levels of IL-4 and IL-6 in AD-like lesional skin were suppressed by AST cream. These findings suggest that AST cream would be an alternative therapeutic agent for AD-like skin diseases.

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