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@article{ART002588455},
author={Mohd Azahar and Qamar Uddin and Munawwar Husain Kazmi and Faiza Khatoon and Nazim Husain},
title={Therapeutic Evaluation of a Topical Unani Formulation, Tila-i Muhāsā in Buthūr Labaniyya (Acne Vulgaris): A Randomized, Controlled Clinical Study},
journal={CELLMED},
issn={3022-6805},
year={2020},
volume={10},
number={2},
pages={15-15},
doi={10.5667/CellMed.2020.0015}

TY - JOUR
AU - Mohd Azahar
AU - Qamar Uddin
AU - Munawwar Husain Kazmi
AU - Faiza Khatoon
AU - Nazim Husain
TI - Therapeutic Evaluation of a Topical Unani Formulation, Tila-i Muhāsā in Buthūr Labaniyya (Acne Vulgaris): A Randomized, Controlled Clinical Study
JO - CELLMED
PY - 2020
VL - 10
IS - 2
PB - Cellmed Orthocellular Medicine and Pharmaceutical Association
SP - 15
EP - 15
SN - 3022-6805
AB - Introduction: Buthūr Labaniyya (Acne vulgaris) is a multifactorial disorder of the pilosebaceous units characterized by non-inflammatory and inflammatory clinical lesions. Several Unani medications have been used for centuries to treat acne. Objectives: Evaluation of safety and efficacy of Tila-i Muhāsā in patients with acne vulgarisMaterials and Methods: This clinical study was conducted in patients with acne vulgaris. Patients applied Tila-i Muhāsā or 5% Benzoyl Peroxide (BPO) once daily for 6 weeks. Assessment of efficacy was carried out by Global Acne Grading System (GAGS) and Patient Global Assessment (PGA) scores. In addition, overall severity of acne was evaluated on a 5-point Cook’s acne grading scale using photographic standards. Assessment of safety was performed through adverse drug reactions, local dermal tolerability, vital signs, and routine laboratory investigations. Results: A total of 60 patients (30 in each group) completed 6 weeks of treatment. The mean percentage reduction in GAGS score at 6 weeks from baseline in Unani group (66.97%) and BPO group (59.09%) was statistically significant (P<0.0001). After 6 weeks of therapy, the mean percentage reduction in PGA score compared to baseline in Unani group (57.44%) and BPO group (50.23%) was statistically significant (P<0.0001). No serious adverse events were reported in both groups; however, mild adverse events occurred more frequently in BPO group (30%) compared to Unani group (10%). Conclusion: Tila-i Muhāsā was found to be effective and safe in the treatment of acne vulgaris. However, further clinical studies with larger sample size and longer duration of therapy need to be conducted.
KW - Acne vulgaris;Buthūr Labaniyya;Unani;Tila-i Muhāsā;Benzoyl peroxide
DO - 10.5667/CellMed.2020.0015
ER -

Mohd Azahar, Qamar Uddin, Munawwar Husain Kazmi, Faiza Khatoon and Nazim Husain. (2020). Therapeutic Evaluation of a Topical Unani Formulation, Tila-i Muhāsā in Buthūr Labaniyya (Acne Vulgaris): A Randomized, Controlled Clinical Study. CELLMED, 10(2), 15-15.

Mohd Azahar, Qamar Uddin, Munawwar Husain Kazmi, Faiza Khatoon and Nazim Husain. 2020, "Therapeutic Evaluation of a Topical Unani Formulation, Tila-i Muhāsā in Buthūr Labaniyya (Acne Vulgaris): A Randomized, Controlled Clinical Study", CELLMED, vol.10, no.2 pp.15-15. Available from: doi:10.5667/CellMed.2020.0015

Mohd Azahar, Qamar Uddin, Munawwar Husain Kazmi, Faiza Khatoon, Nazim Husain "Therapeutic Evaluation of a Topical Unani Formulation, Tila-i Muhāsā in Buthūr Labaniyya (Acne Vulgaris): A Randomized, Controlled Clinical Study" CELLMED 10.2 pp.15-15 (2020) : 15.

Mohd Azahar, Qamar Uddin, Munawwar Husain Kazmi, Faiza Khatoon, Nazim Husain. Therapeutic Evaluation of a Topical Unani Formulation, Tila-i Muhāsā in Buthūr Labaniyya (Acne Vulgaris): A Randomized, Controlled Clinical Study. 2020; 10(2), 15-15. Available from: doi:10.5667/CellMed.2020.0015

Mohd Azahar, Qamar Uddin, Munawwar Husain Kazmi, Faiza Khatoon and Nazim Husain. "Therapeutic Evaluation of a Topical Unani Formulation, Tila-i Muhāsā in Buthūr Labaniyya (Acne Vulgaris): A Randomized, Controlled Clinical Study" CELLMED 10, no.2 (2020) : 15-15.doi: 10.5667/CellMed.2020.0015

Mohd Azahar; Qamar Uddin; Munawwar Husain Kazmi; Faiza Khatoon; Nazim Husain. Therapeutic Evaluation of a Topical Unani Formulation, Tila-i Muhāsā in Buthūr Labaniyya (Acne Vulgaris): A Randomized, Controlled Clinical Study. CELLMED, 10(2), 15-15. doi: 10.5667/CellMed.2020.0015

Mohd Azahar; Qamar Uddin; Munawwar Husain Kazmi; Faiza Khatoon; Nazim Husain. Therapeutic Evaluation of a Topical Unani Formulation, Tila-i Muhāsā in Buthūr Labaniyya (Acne Vulgaris): A Randomized, Controlled Clinical Study. CELLMED. 2020; 10(2) 15-15. doi: 10.5667/CellMed.2020.0015

Mohd Azahar, Qamar Uddin, Munawwar Husain Kazmi, Faiza Khatoon, Nazim Husain. Therapeutic Evaluation of a Topical Unani Formulation, Tila-i Muhāsā in Buthūr Labaniyya (Acne Vulgaris): A Randomized, Controlled Clinical Study. 2020; 10(2), 15-15. Available from: doi:10.5667/CellMed.2020.0015

Mohd Azahar, Qamar Uddin, Munawwar Husain Kazmi, Faiza Khatoon and Nazim Husain. "Therapeutic Evaluation of a Topical Unani Formulation, Tila-i Muhāsā in Buthūr Labaniyya (Acne Vulgaris): A Randomized, Controlled Clinical Study" CELLMED 10, no.2 (2020) : 15-15.doi: 10.5667/CellMed.2020.0015