This study tried to analyze differences in the recognition of career choice, satisfaction, and major adjustment among university students based on their majors. That is to say, this study examined differences in the recognition of career choice, satisfaction, and major adjustment among university students in health-care majors and social science majors. As a result of the analysis, first, there were no significant differences in the career recognition among other career choice factors, but differences between the two types of majors were found in learning preference and activity engagement factors. That is to say, the health-care majoring students were more sensitive to learning preference factors than the social science majoring students in that the former were interested in major classes and found themselves fit to major classes, and the formerwere also susceptible to activity engagement factors as they more frequently participated in major-related job events and club activities than the latter. Second, there were significant differences in major satisfaction and department satisfaction among other career satisfaction factors. That is to say, it turned out that the health-care majoring students were highly satisfied with their majors and with their departments. Third, there were no significant differences in major performance among other major adjustment factors, but there were significant differences in major immersion. That is to say, it turned out that the social science majoring students were highly immersed in their major work. As for other results, the health-care majoring students were much higher in career choice and satisfaction, but the social science majoring students showed higher immersion in their majors. From this, we can tell that career choice and satisfaction do not necessarily have similar influence on major adjustment though a conjecture in this study was that there would be differences in career choice, satisfaction, and major adjustment between the major types. Fourth, as for gender differences, the male students had high recognition of career choice and satisfaction, while their female counterparts had high recognition of major adjustment. Fifth, as for grade years, students in higher grade years had higher recognition of career, but had lower satisfaction with their departments. On the other hand, as a result of the analysis of the relations among career choice, satisfaction, and major adjustment, it turned out that career choice and satisfaction had significant influence on major adjustment in the health-care majoring students, but not in the social science majoring students. It is conjectured that this was because the former were highly satisfied with their career as they well selected their career, and hence based on this, they were well adjusted to their majors.