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Effects of Midazolam with Sevoflurane Insufflation Sedation on Concomitant Administration in Pediatric Patients : A Preliminary Study

지성인 1 Jong-Soo Kim ORD ID 1

1단국대학교

Accredited

ABSTRACT

Patients with extreme anxiety who are unable to cope with dental treatment under non-pharmacologicalbehavioral management method may require sedation, or other forms pharmacological behavioral managementmethod. The aim of this retrospective study was to investigate the effect of concomitant administration of 0.1mg/kg intramuscular midazolam with or without sevoflurane insufflation sedation on sedation depth andcardiopulmonary function in pediatric patients. We analysed the records of anesthesia on patients who receiveddental treatment under deep sedation using sevoflurane insufflation from January 2013 to March 2014. Thirtysixchildren, aged 3 to 6 years, undergoing dental treatment were sedated using either sevoflurane insufflationalone (Group S, n = 18) or a combination of intramuscular injection of 0.1 mg/kg midazolam plus sevofluraneinsufflation (Group SM, n = 18). Upon comparison, the average entropy value of group SM was lower than thatof group S, but there were no statistically significant difference between the two groups (p > 0.05). The averageheart rate and mean arterial pressure of group SM were higher than those of group S (p < 0.05). Concomitantintramuscular injection of 0.1 mg/kg midazolam with sevoflurane insufflation sedation is not sufficient to enhancethe quality of sedation.

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* References for papers published after 2023 are currently being built.