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Bioactivity behavior of Si and Mg ion-substituted biphasic calcium phosphate powders

  • Journal of the Korean Crystal Growth and Crystal Technology
  • Abbr : J. Korean Cryst. Growth Cryst. Technol.
  • 2012, 22(2), pp.92~98
  • DOI : 10.6111/JKCGCT.2012.22.2.092
  • Publisher : The Korea Association Of Crystal Growth, Inc.
  • Research Area : Engineering > Materials Science and Engineering

김태완 1,  김동헌 1,  진형호 1,  이헌수 2,  PARK,HONG-CHAE 1,  Seog-Young Yoon 1

1부산대학교
2대구공업대학교

Accredited

ABSTRACT

The co-precipitation technique has been applied to synthesize biphasic calcium phosphate (BCP). Ca(NO3)2 · 4H2O,(NH4)2HPO4, TEOS and Mg(NO3)2 · 6H2O as the starting materials was used. After the heat treatment of powder crystalline phases HAp and β-TCP analysis showed a mixed phase. The overall spectra appear to have mainly two modes corresponding to characteristic PO43− and OH− groups. After immersion in Hanks’ Balanced Salt Solution (HBSS) for 1week a precipitation started to be formed with individual small granules on the specimen surface. An MTT assay indicated that ionic substituted BCP powders had no cytotoxic effects on MG-63 cells, and that they have good biocompatibility.

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