@article{ART003215958},
author={Juwoong Jang and DeukYong Lee},
title={Biological stability and transplantation test of PLLA/gelatin hybrid polymer as a barrier to periodontal tissue regeneration},
journal={Journal of the Korean Crystal Growth and Crystal Technology},
issn={1225-1429},
year={2025},
volume={35},
number={2},
pages={55-62},
doi={10.6111/JKCGCT.2025.35.2.055}
TY - JOUR
AU - Juwoong Jang
AU - DeukYong Lee
TI - Biological stability and transplantation test of PLLA/gelatin hybrid polymer as a barrier to periodontal tissue regeneration
JO - Journal of the Korean Crystal Growth and Crystal Technology
PY - 2025
VL - 35
IS - 2
PB - The Korea Association Of Crystal Growth, Inc.
SP - 55
EP - 62
SN - 1225-1429
AB - The feasibility of the PLLA/gelatin absorbable periodontal tissue regeneration barrier membrane was investigated by examining the biological stability (cytotoxicity, guinea pig maximization test, intradermal test, acute systemic toxicity, and chromosome abnormalty test) and efficacy evaluation using a rat calvarial defect model. As a result of the biological stability evaluation, no abnormal results were observed, indicating excellent biocompatibility. In addition, the transplantation test using a bone defect model for 2 weeks exhibited no significant difference in the volume of regenerated bone and average weight loss of more than 20 %. As a result of the skull observation, the barrier membrane was well fixed to the transplantation site, properly shielding the bone defect area, and no inflammatory response was observed. The experimental results suggest that PLLA/gelain barrier membrane was well suited for absorbable periodontal tissue regeneration.
KW - PLLA;Gelatin;Periodontal tissue regeneration barrier membrane;Biological stability;Transplantation tes
DO - 10.6111/JKCGCT.2025.35.2.055
ER -
Juwoong Jang and DeukYong Lee. (2025). Biological stability and transplantation test of PLLA/gelatin hybrid polymer as a barrier to periodontal tissue regeneration. Journal of the Korean Crystal Growth and Crystal Technology, 35(2), 55-62.
Juwoong Jang and DeukYong Lee. 2025, "Biological stability and transplantation test of PLLA/gelatin hybrid polymer as a barrier to periodontal tissue regeneration", Journal of the Korean Crystal Growth and Crystal Technology, vol.35, no.2 pp.55-62. Available from: doi:10.6111/JKCGCT.2025.35.2.055
Juwoong Jang, DeukYong Lee "Biological stability and transplantation test of PLLA/gelatin hybrid polymer as a barrier to periodontal tissue regeneration" Journal of the Korean Crystal Growth and Crystal Technology 35.2 pp.55-62 (2025) : 55.
Juwoong Jang, DeukYong Lee. Biological stability and transplantation test of PLLA/gelatin hybrid polymer as a barrier to periodontal tissue regeneration. 2025; 35(2), 55-62. Available from: doi:10.6111/JKCGCT.2025.35.2.055
Juwoong Jang and DeukYong Lee. "Biological stability and transplantation test of PLLA/gelatin hybrid polymer as a barrier to periodontal tissue regeneration" Journal of the Korean Crystal Growth and Crystal Technology 35, no.2 (2025) : 55-62.doi: 10.6111/JKCGCT.2025.35.2.055
Juwoong Jang; DeukYong Lee. Biological stability and transplantation test of PLLA/gelatin hybrid polymer as a barrier to periodontal tissue regeneration. Journal of the Korean Crystal Growth and Crystal Technology, 35(2), 55-62. doi: 10.6111/JKCGCT.2025.35.2.055
Juwoong Jang; DeukYong Lee. Biological stability and transplantation test of PLLA/gelatin hybrid polymer as a barrier to periodontal tissue regeneration. Journal of the Korean Crystal Growth and Crystal Technology. 2025; 35(2) 55-62. doi: 10.6111/JKCGCT.2025.35.2.055
Juwoong Jang, DeukYong Lee. Biological stability and transplantation test of PLLA/gelatin hybrid polymer as a barrier to periodontal tissue regeneration. 2025; 35(2), 55-62. Available from: doi:10.6111/JKCGCT.2025.35.2.055
Juwoong Jang and DeukYong Lee. "Biological stability and transplantation test of PLLA/gelatin hybrid polymer as a barrier to periodontal tissue regeneration" Journal of the Korean Crystal Growth and Crystal Technology 35, no.2 (2025) : 55-62.doi: 10.6111/JKCGCT.2025.35.2.055
2