@article{ART002063487},
author={송미영},
title={The Effects of Cinnamomum cassia Blume, Aconitum carmichaeli Debx, and Pueraria lobata Benth on Glucose and Energy Metabolism in C2C12 Myotubes},
journal={Journal of Korean Medicine for Obesity Research},
issn={1976-9334},
year={2015},
volume={15},
number={2},
pages={131-136}
TY - JOUR
AU - 송미영
TI - The Effects of Cinnamomum cassia Blume, Aconitum carmichaeli Debx, and Pueraria lobata Benth on Glucose and Energy Metabolism in C2C12 Myotubes
JO - Journal of Korean Medicine for Obesity Research
PY - 2015
VL - 15
IS - 2
PB - The Society of Korean Medicine for Obesity Research
SP - 131
EP - 136
SN - 1976-9334
AB - Objectives: The prevalence of obesity and metabolic syndrome is increasing worldwide. Regulationof cellular energy metabolis has the potential to be manipulated therapeutically to serveas a target for obesity and insulin resistance. Skeletal muscle is regarded as a target for regulationof energy metabolism and insulin resistance. In this study, the authors investigated the regulatoryeffect of (Cinnamomum cassia Blume, CCB), Aconitum carmichaeli Debx (ACD), and Benth(Pueraria lobata Benth, PLB) on energy and glucose metabolism in C2C12 myotubes.
Methods: The water extracts of CCB, ACD, and PLB (0.5 mg/ml) were treated in differentiatedC2C12 myotubes. The expressions of adenosine monophosphate-activated protein kinase(AMPK) and phosphorylation AMPK were detected with western blotting. Glucose metabolismwas investigated with glucose uptake assay and glucose consumption assay, total adenosinetriphosphate (ATP) content was also analyzed.
Results: CCB, ACD, and PLB activated the phophorylation of AMPK, they also increased theglucose metabolism and total ATP contents in C2C12 myotubes.
Conclusions: This study suggests that CCB, ACD, and PLB have the potential to increase energyand glucose metabolism in skeletal muscle.
KW - Cinnamomum cassia Blume;Aconitum carmichaeli Debx;Pueraria lobata Benth;Glucose;Energy;C2C12
DO -
UR -
ER -
송미영. (2015). The Effects of Cinnamomum cassia Blume, Aconitum carmichaeli Debx, and Pueraria lobata Benth on Glucose and Energy Metabolism in C2C12 Myotubes. Journal of Korean Medicine for Obesity Research, 15(2), 131-136.
송미영. 2015, "The Effects of Cinnamomum cassia Blume, Aconitum carmichaeli Debx, and Pueraria lobata Benth on Glucose and Energy Metabolism in C2C12 Myotubes", Journal of Korean Medicine for Obesity Research, vol.15, no.2 pp.131-136.
송미영 "The Effects of Cinnamomum cassia Blume, Aconitum carmichaeli Debx, and Pueraria lobata Benth on Glucose and Energy Metabolism in C2C12 Myotubes" Journal of Korean Medicine for Obesity Research 15.2 pp.131-136 (2015) : 131.
송미영. The Effects of Cinnamomum cassia Blume, Aconitum carmichaeli Debx, and Pueraria lobata Benth on Glucose and Energy Metabolism in C2C12 Myotubes. 2015; 15(2), 131-136.
송미영. "The Effects of Cinnamomum cassia Blume, Aconitum carmichaeli Debx, and Pueraria lobata Benth on Glucose and Energy Metabolism in C2C12 Myotubes" Journal of Korean Medicine for Obesity Research 15, no.2 (2015) : 131-136.
송미영. The Effects of Cinnamomum cassia Blume, Aconitum carmichaeli Debx, and Pueraria lobata Benth on Glucose and Energy Metabolism in C2C12 Myotubes. Journal of Korean Medicine for Obesity Research, 15(2), 131-136.
송미영. The Effects of Cinnamomum cassia Blume, Aconitum carmichaeli Debx, and Pueraria lobata Benth on Glucose and Energy Metabolism in C2C12 Myotubes. Journal of Korean Medicine for Obesity Research. 2015; 15(2) 131-136.
송미영. The Effects of Cinnamomum cassia Blume, Aconitum carmichaeli Debx, and Pueraria lobata Benth on Glucose and Energy Metabolism in C2C12 Myotubes. 2015; 15(2), 131-136.
송미영. "The Effects of Cinnamomum cassia Blume, Aconitum carmichaeli Debx, and Pueraria lobata Benth on Glucose and Energy Metabolism in C2C12 Myotubes" Journal of Korean Medicine for Obesity Research 15, no.2 (2015) : 131-136.