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@article{ART002115523},
author={송미영 and Hyo Won, Jung and Yong-Ki Park},
title={Antiobesity Effect of Water Extract of Coix lacrymajobi var. mayuen in High Fat Fed C5BL/6 Mice},
journal={Journal of Korean Medicine for Obesity Research},
issn={1976-9334},
year={2016},
volume={16},
number={1},
pages={27-35}

TY - JOUR
AU - 송미영
AU - Hyo Won, Jung
AU - Yong-Ki Park
TI - Antiobesity Effect of Water Extract of Coix lacrymajobi var. mayuen in High Fat Fed C5BL/6 Mice
JO - Journal of Korean Medicine for Obesity Research
PY - 2016
VL - 16
IS - 1
PB - The Society of Korean Medicine for Obesity Research
SP - 27
EP - 35
SN - 1976-9334
AB - Objectives: This study investigated the effects of water extract of Coix lacrymajobi var. mayuen on obesity and its associated factors in high fat diet (HFD) induced obese mice. Methods: Male C5BL/6 mice were randomly assigned to 4 groups, normal group (chow diet), a HFD, HFD with water extract of Coix lacrymajobi var. mayuen 100 mg/kg (W-Coix), and HFD with phentermine 5 mg/kg (Phen) as positive control. Body weight, food intake, fasting blood glucose were checked every week and then organs, blood serums were collected after 16 weeks of treatment. Results: Body weight and adipocyte size were significantly lesser in W-Coix than in HFD group; however energy efficiency in W-Coix were not different with HFD. The oral glucose tolerance test, serum glucose and insulin were significantly decreased in W-Coix, also lipid accumulations in liver tissue and lipid levels (total cholesterol, high density lipoprotein-cholesterol) were improved with W-Coix treatment. However skeletal muscle loss with HFD was not changed in W-Coix compared with HFD group. Conclusions: The W-Coix treatment decreased body weight, adipocyte size and it is associated with improved glucose and lipid metabolism. Further studies are needed to know the mechanism of antiobesity in W-Coix.
KW - Coix lacrymajobi var. mayuen;C5BL/6 mouse;Obesity;Glucose;Lipid;Liver
DO -
UR -
ER -

송미영, Hyo Won, Jung and Yong-Ki Park. (2016). Antiobesity Effect of Water Extract of Coix lacrymajobi var. mayuen in High Fat Fed C5BL/6 Mice. Journal of Korean Medicine for Obesity Research, 16(1), 27-35.

송미영, Hyo Won, Jung and Yong-Ki Park. 2016, "Antiobesity Effect of Water Extract of Coix lacrymajobi var. mayuen in High Fat Fed C5BL/6 Mice", Journal of Korean Medicine for Obesity Research, vol.16, no.1 pp.27-35.

송미영, Hyo Won, Jung, Yong-Ki Park "Antiobesity Effect of Water Extract of Coix lacrymajobi var. mayuen in High Fat Fed C5BL/6 Mice" Journal of Korean Medicine for Obesity Research 16.1 pp.27-35 (2016) : 27.

송미영, Hyo Won, Jung, Yong-Ki Park. Antiobesity Effect of Water Extract of Coix lacrymajobi var. mayuen in High Fat Fed C5BL/6 Mice. 2016; 16(1), 27-35.

송미영, Hyo Won, Jung and Yong-Ki Park. "Antiobesity Effect of Water Extract of Coix lacrymajobi var. mayuen in High Fat Fed C5BL/6 Mice" Journal of Korean Medicine for Obesity Research 16, no.1 (2016) : 27-35.

송미영; Hyo Won, Jung; Yong-Ki Park. Antiobesity Effect of Water Extract of Coix lacrymajobi var. mayuen in High Fat Fed C5BL/6 Mice. Journal of Korean Medicine for Obesity Research, 16(1), 27-35.

송미영; Hyo Won, Jung; Yong-Ki Park. Antiobesity Effect of Water Extract of Coix lacrymajobi var. mayuen in High Fat Fed C5BL/6 Mice. Journal of Korean Medicine for Obesity Research. 2016; 16(1) 27-35.

송미영, Hyo Won, Jung, Yong-Ki Park. Antiobesity Effect of Water Extract of Coix lacrymajobi var. mayuen in High Fat Fed C5BL/6 Mice. 2016; 16(1), 27-35.

송미영, Hyo Won, Jung and Yong-Ki Park. "Antiobesity Effect of Water Extract of Coix lacrymajobi var. mayuen in High Fat Fed C5BL/6 Mice" Journal of Korean Medicine for Obesity Research 16, no.1 (2016) : 27-35.