Clinical Outcomes after Modified Fasting Therapy Supplied with Gamrosu: A Retrospective Observational Study (감로수(甘露水)를 이용한 절식요법의 임상결과에 관한 후향적 관찰연구)

신승우; 김동환; 신현택; Oh， Dal-Seok (오달석)

Clinical Outcomes after Modified Fasting Therapy Supplied with Gamrosu: A Retrospective Observational Study

Journal of Korean Medicine for Obesity Research
Abbr : J Korean Med Obes Res
2016, 16(1), pp.36-49
Publisher : The Society of Korean Medicine for Obesity Research
Research Area : Medicine and Pharmacy > Korean Medicine
Published : June 30, 2016

신승우 ¹, 김동환 ², 신현택 ³, Oh， Dal-Seok ⁴

¹신강한의원
²아름다운여성한의원
³가로세로한의원
⁴한국한의학연구원

Accredited

ABSTRACT

Objectives: Two historical evidence supported the concept of Gamrosu. The first one was Jeho-tang, a selected thirst quencher in Chosun Dynasty and the second one was Saeng- Maek-san, Dongeuibogam’s recommendation as one of the qi-vigorating summer beverages. Gamrosu is a modified fasting therapy beverage which is manufactured from those two prescriptions and the carbohydrates (420.6 kcal/d). A retrospective observational study was conducted to evaluate the clinical outcomes. Methods: Thirty-three cases were reviewed at three local Korean Medical clinics that each site’s participant has finished the modified fasting for 10 consecutive days. Clinical outcomes were reviewed at pre- and post-fasting sessions by retrieving the changes of body composition, blood pressure, blood chemistries & urine tests, and subjective symptoms & fatigue scores. Results: Demographics of the observed participants were 17 of male and 16 of female. Post-Gamrosu session, −6.89% of body weight, −8.97% of body fat mass were reduced with the nutrition indices being improved (P＜0.001). −8.72% of systolic blood pressure, −39.86% of serum triglyceride, −6.75% of fast blood sugar and −8.12% of waist circumference were improved (P＜0.05). The levels of high sensitivity C-reactive protein (−58.34%), CRP (−43.55%) and eosinophil (−21.30%) showed the significant diminished profiles (P＜0.05). Liver/kidney functions and the standard of electrolytes were maintained within normal range in stable manners. The fatigue scale scores indicated significant lower scores. Conclusions: Taken together, obesity-related clinical outcomes after a modified fasting therapy with Gamrosu were sufficiently feasible and the observed findings should be considered for further prospective clinical studies.

KEYWORDS

Gamrosu, Modified fasting, Obesity, Metabolic syndrome, Inflammation

Citation status

* References for papers published after 2023 are currently being built.

[journal] 윤영흠 / 2014 / A Study on Thought of Regimen specified in 『Gyeokchiyeoron』 / 대한한의학원전학회지 / 대한한의학원전학회 27(4) : 153~169

[journal] Heilbronn LK / 2003 / Calorie restriction and aging: review of the literature and implications for studies in humans / Am J Clin Nutr 78(3) : 361~369

[journal] Michalsen A / 2013 / Fasting therapy for treating and preventing disease-current state of evidence / Forsch Komplementmed 20(6) : 444~453

[journal] Wilhelmi de Toledo F / 2013 / Fasting therapy: an expert panel update of the 2002 consensus guidelines / Forsch Komplementmed 20(6) : 434~443

[book] Korean Association of Oriental Rehabilitation Medicine / 2005 / Text book of oriental rehabilitation medicine / Koonja Publisher : 376~384

[journal] Shin SU / 2003 / The clinical study on the effect of reduction in body weight and the change of body composition after fasting therapy / J Korean Med Obes Res 3(1) : 25~35

[thesis] Kim KW / 2013 / Clinical case series on the changes of body composition and blood chemistry after modified fasting therapy: a retrospective observational study / Master / Kyunghee University

[journal] 박원일 / 2002 / Effect of a traditional korean very-low-calorie diet on obese patients / 대한내과학회지 / 대한내과학회 62(3) : 2~257

[journal] Hwang EH / 2004 / The clinical study of comparison efficacy between the vegetable ferment extract and the spring water in fasting therapy / J Orient Rehab Med 14(2) : 119~128

[thesis] Nho JS / 2014 / Very low calorie diet combining fasting with juice for obese patients / Master / Kyunghee University

[journal] Kim DB / 2008 / The effect of zymolysis-dietotherapy with herbal formula on the obesity / Daejeon Univ Inst Korean Med 17(1) : 75~82

[journal] Rothacker DQ / 2001 / Liquid meal replacement vs traditional food: a potential model for women who cannot maintain eating habit change / J Am Diet Assoc 101(3) : 345~347

[journal] 이정민 / 2011 / Effects of Modified Fasting Therapy Using Fermented Herbal Medicine on Changes of Body Compositions / 한방재활의학과학회지 / 한방재활의학과학회 21(3) : 33~43

[journal] 오달석 / 2015 / A Pilot Study to Develop Gamrosu, a Modified Fasting Therapy Beverage: Case Series / 한방비만학회지 / 한방비만학회 15(2) : 153~161

[journal] Lee SB / 1996 / The clinical study on protein analysis during fasting therapy period / J Orient Rehab Med 6(1) : 317~326

[journal] 김고운 / 2010 / A Clinical Case Study on the Changes of Body Composition and Blood Chemistry after Modified Fasting Therapy in a Patient with Obesity / 한방비만학회지 / 한방비만학회 10(1) : 49~56

[journal] 정원석 / 2011 / A Case Report on the Jaundice Occurred during the Modified Fasting Therapy Period : The Gilbert's Syndrome / 한방비만학회지 / 한방비만학회 11(2) : 69~74

[journal] 정순관 / 2008 / The Retrospective Study on Modified Fasting Therapy in Inpatients / 한방재활의학과학회지 / 한방재활의학과학회 18(4) : 171~187

[journal] Kwon YY / 1995 / The clinical studies on obesity by fasting therapy / J Orient Rehab Med 5(1) : 225~260

[journal] An JW / 2001 / A clinical study on the body composition changes after fasting therapy / J Orientl Rehab Med 11(1) : 29~43

[journal] Yeom SR / 2001 / The clinical study on the change of bone mineral density during fasting therapy / J Orient Rehab Med 11(2) : 27~37

[journal] 지명순 / 2006 / 제호탕의 장내 세균 및 면역 활성에 미치는 연구 / 한국식품과학회지 / 한국식품과학회 38(1) : 104~108

[journal] 정세현 / 2012 / Antioxidant and antidiabetic Activity of Jehotang according to Different Cooking Methods / 한국조리학회지 / 한국조리학회 18(5) : 233~242

[journal] Park KJ / 2002 / Saeng-Maek-San, a medicinal herb complex, protects liver cell damage induced by alcohol / Biol Pharm Bull 25(11) : 1451~1455

[thesis] Ju IH / 2013 / Effects of Saengmaek-san on osteoclastogenesis and gene expression / Master / Wonkwang university

[journal] 이상엽 / 2005 / Predictive Values of Body Mass Index and Waist Circumference for Cardiovascular Risk Factors in Korean : Comparison with American Population / Korean Journal of Health Promotion / 대한임상건강증진학회 5(2) : 97~113

[journal] Goldhamer A / 2001 / Medically supervised water-only fasting in the treatment of hypertension / J Manipulative Physiol Ther 24(5) : 335~339

[journal] Cho SI / 1994 / The effect of the fasting on body weight, blood pressure, blood cell count and blood chemistry in people / J Korean Acad Fam Med 15(12) : 1128~1140

[journal] Ryu EK / 1989 / Clinical studies on hematologic change by fasting therapy / J Korean Med 10(1) : 148~153

[book] The Korean Association of Internal Medicine / 2003 / Harrison's internal medicine / MIP : 460~

[journal] Kim BH / 2005 / Diagnostic approach to abnormal liver tests in apparently healthy subjects / J Korean Med Assoc 48(5) : 414~422

[journal] Samra M / 2012 / False estimates of elevated creatinine / The Perm J 16(2) : 51~52

[journal] Watts NB / 1990 / Carbohydrate tolerance improves with fasting in obese subjects with noninsulin-dependent (type II) diabetes / Am J Med Sci 299(4) : 250~256

[journal] Kang HJ / 1997 / Dietary fiber and cholesterol metabolism / J Korean Soc Food Sci Nutr 26(2) : 358~369

[journal] Sävendahl L / 1999 / Fasting increases serum total cholesterol, LDL cholesterol and apolipoprotein b in healthy, nonobese humans / J Nutr 129(11) : 2005~2008

[journal] Min WK / 2008 / Factors affecting the difference between the low-density lipoprotein cholesterol concentrations measured directly and calculated using the friedewald formula / J Lab Med Qual Assur 30(2) : 233~235

[journal] 박전수 / 2009 / The Role of C-reactive Protein as a Infl ammation-related Factor in Metabolic Syndrome / Korean Journal of Family Medicine / 대한가정의학회 30(6) : 449~456

[journal] Son JC / 2003 / The most associated risk factor of the metabolic syndrome with C-reactive protein / Korean J Obes 12(1) : 15~23

[journal] Lim KH / 1999 / Metabolic adaptation to starvation / Inje Med J 20 : 197~208

[journal] Edwards C / 2014 / D-beta-hydroxybutyrate extends lifespan in C. elegans / Aging(Albany NY) 6(8) : 621~644

[journal] Jing MJ / 2016 / Reliability and construct validity of two versions of Chalder Fatigue Scale among the general population in mainland China / Int J Environ Res Public Health 13(1) : 147~

KJCKorea
Journal Central

Journal of Korean Medicine for Obesity Research 2023 KCI Impact Factor : 0.43