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Preparation and evaluation of hydrogels containing Loratadine for the treatment of allergic diseases

  • Journal of The Korea Society of Computer and Information
  • Abbr : JKSCI
  • 2024, 29(11), pp.311-316
  • DOI : 10.9708/jksci.2024.29.11.311
  • Publisher : The Korean Society Of Computer And Information
  • Research Area : Engineering > Computer Science
  • Received : November 4, 2024
  • Accepted : November 25, 2024
  • Published : November 29, 2024

Chul-Tae Kim 1 Kwang-Soon Kang 2

1건양대학교
2대전보건대학교

Accredited

ABSTRACT

Anti-histamines are drugs used to relieve allergic diseases such as urticaria. Loratadine is a second-generation ant-ihistamine that works better with fewer side effects such as sleepiness and headaches. However, even if the effect is good, it takes a long time for the effect to take a pill. The method of delivering drugs to the skin is a way to overcome these shortcomings and show quick effects. Therefore, hydrogels containing Loratadine were produced and their properties were evaluated. The content of Loratadine was more than 98%, and the uniformity of the contents was good. When manufacturing hydrogels, the higher the amount of carbomer, the higher the viscosity of the gel. As a result of evaluation of the prepared hydrogel, it was obtained that most of it fell within the range of commercially available gels.

Citation status

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