Antimicrobial activity of Prunus mume extract to oral microbes (매실추출물(PME)의 구강 미생물에 대한 항균작용)

Jong-Hwa Jang (장종화); 김영인; 이현

doi:10.13065/jksdh.2014.14.01.109

Antimicrobial activity of Prunus mume extract to oral microbes

Journal of Korean society of Dental Hygiene
Abbr : J Korean Soc Dent Hyg
2014, 14(1), pp.109~115
DOI : 10.13065/jksdh.2014.14.01.109
Publisher : Korean Society of Dental Hygiene
Research Area : Medicine and Pharmacy > Dentistry

Jong-Hwa Jang ¹, 김영인 ², 이현 ³

¹한서대학교
²한서대학교대학원 치위생학과
³서울대학교병원 진단검사의학과

Accredited

ABSTRACT

Objectives : Prunus mume has been used for the folk medicine from old times. The purposeof the study was to investigate the antimicrobial activity of prunus mume extract to various oralmicrobes. Methods : This study was carried out to examine the antimicrobial effect of Prunus mumeextract against oral microbes. Data were collected using a Dentocult SM Strip mutans and DentocultLB Strip mutans from April 5 to May 4, 2013. A total of 36 experimental and 32 control groupwere selected for this study. Results : The MIC of Prunus mume extract was tested for 0.39% in S. mutans, S. salivariusand S. auerus, 0.78% in S. mitis, S. equi and E. coli. In vivo, experimental group showed significantlythe lower Streptococcus mutans levels by the use of the gum contained Prunus mume extractfrom 15 days compared with control group(p=0.012). The reduction was more significant inLactobacilli level of the experimental group than the control group(p=0.022). Conclusions : These findings suggest that the oral products containing Prunus mume extractsis effective in preventing oral diseases.

KEYWORDS

antimicrobial activity, minimum inhibition concentration(MIC), minimum bactericidal concentration(MBC), oral microbes, Prunus mume extract (PME)

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