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Antimicrobial activity of Prunus mume extract to oral microbes

Jong-Hwa Jang 1 김영인 2 이현 3

1한서대학교
2한서대학교대학원 치위생학과
3서울대학교병원 진단검사의학과

Accredited

ABSTRACT

Objectives : Prunus mume has been used for the folk medicine from old times. The purposeof the study was to investigate the antimicrobial activity of prunus mume extract to various oralmicrobes. Methods : This study was carried out to examine the antimicrobial effect of Prunus mumeextract against oral microbes. Data were collected using a Dentocult SM Strip mutans and DentocultLB Strip mutans from April 5 to May 4, 2013. A total of 36 experimental and 32 control groupwere selected for this study. Results : The MIC of Prunus mume extract was tested for 0.39% in S. mutans, S. salivariusand S. auerus, 0.78% in S. mitis, S. equi and E. coli. In vivo, experimental group showed significantlythe lower Streptococcus mutans levels by the use of the gum contained Prunus mume extractfrom 15 days compared with control group(p=0.012). The reduction was more significant inLactobacilli level of the experimental group than the control group(p=0.022). Conclusions : These findings suggest that the oral products containing Prunus mume extractsis effective in preventing oral diseases.

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