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@article{ART002162387},
author={Park Jung-Eun and Park Yong Duk and Tae Kee HONG and Jong-Hwa Jang},
title={Residue by elapsed time of non-enzymatic antioxidants in dentifrice},
journal={Journal of Korean society of Dental Hygiene},
issn={2287-1705},
year={2016},
volume={16},
number={5},
pages={783-790},
doi={}

TY - JOUR
AU - Park Jung-Eun
AU - Park Yong Duk
AU - Tae Kee HONG
AU - Jong-Hwa Jang
TI - Residue by elapsed time of non-enzymatic antioxidants in dentifrice
JO - Journal of Korean society of Dental Hygiene
PY - 2016
VL - 16
IS - 5
PB - Korean Society of Dental Hygiene
SP - 783
EP - 790
SN - 2287-1705
AB - Objectives: The purpose of this study is to evaluate the non-enzymatic antioxidants stabilities in dentifrices by ascorbic acid and tocopherol according to the chemical condition. Methods: For the analysis of two antioxidants, HPLC UV detector system was used. HPLC was performed using sodium sulfate, acetonitrile(ACN), methanol(MeOH) and measuring absorbance at 240-295 nm. To confirm general pH reaction of two compounds, buffer solution was prepared for the analysis. The dentifrice was titrated by pH so as to examine the change of elapsed time in dentifrice. Linearity of calibration curve of two antioxidants was measured. Results: Each compound showed good linearity at optimized wavelength as well as showing good precision. General pH reaction of two antioxidants was examined. Ascorbic acid showed the highest residue(63.23%) at pH 10 and the lowest residue(2.77%) at pH 4. Tocopherol showed the highest residue(55.70%) at pH 7 and the lowest residue(3.31%) at pH 4. As a result of changing elapsed time of antioxidants in dentifrice by pH, components were remained stably at low temperature(39.2℉) and pH 7. Conclusions: It is necessary to keep dentifrice including ascorbic acid and tocopherol, and non-enzymatic antioxidants at pH 7 and low temperature for improving chemical stability.
KW - antioxidants;change of elapsed time;dentifrice;non-enzymatic antioxidants;stability
DO -
ER -

Park Jung-Eun, Park Yong Duk, Tae Kee HONG and Jong-Hwa Jang. (2016). Residue by elapsed time of non-enzymatic antioxidants in dentifrice. Journal of Korean society of Dental Hygiene, 16(5), 783-790.

Park Jung-Eun, Park Yong Duk, Tae Kee HONG and Jong-Hwa Jang. 2016, "Residue by elapsed time of non-enzymatic antioxidants in dentifrice", Journal of Korean society of Dental Hygiene, vol.16, no.5 pp.783-790. Available from: doi:

Park Jung-Eun, Park Yong Duk, Tae Kee HONG, Jong-Hwa Jang "Residue by elapsed time of non-enzymatic antioxidants in dentifrice" Journal of Korean society of Dental Hygiene 16.5 pp.783-790 (2016) : 783.

Park Jung-Eun, Park Yong Duk, Tae Kee HONG, Jong-Hwa Jang. Residue by elapsed time of non-enzymatic antioxidants in dentifrice. 2016; 16(5), 783-790. Available from: doi:

Park Jung-Eun, Park Yong Duk, Tae Kee HONG and Jong-Hwa Jang. "Residue by elapsed time of non-enzymatic antioxidants in dentifrice" Journal of Korean society of Dental Hygiene 16, no.5 (2016) : 783-790.doi:

Park Jung-Eun; Park Yong Duk; Tae Kee HONG; Jong-Hwa Jang. Residue by elapsed time of non-enzymatic antioxidants in dentifrice. Journal of Korean society of Dental Hygiene, 16(5), 783-790. doi:

Park Jung-Eun; Park Yong Duk; Tae Kee HONG; Jong-Hwa Jang. Residue by elapsed time of non-enzymatic antioxidants in dentifrice. Journal of Korean society of Dental Hygiene. 2016; 16(5) 783-790. doi:

Park Jung-Eun, Park Yong Duk, Tae Kee HONG, Jong-Hwa Jang. Residue by elapsed time of non-enzymatic antioxidants in dentifrice. 2016; 16(5), 783-790. Available from: doi:

Park Jung-Eun, Park Yong Duk, Tae Kee HONG and Jong-Hwa Jang. "Residue by elapsed time of non-enzymatic antioxidants in dentifrice" Journal of Korean society of Dental Hygiene 16, no.5 (2016) : 783-790.doi: