Journal of Korean society of Dental Hygiene 2023 KCI Impact Factor : 0.8
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pISSN : 2287-1705 / eISSN : 2288-2294
- https://journal.kci.go.kr/jksdh
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Association between dental X-ray exposure and the thyroid cancer risk: A meta-analysis of case–control studies
- Journal of Korean society of Dental Hygiene
- Abbr : J Korean Soc Dent Hyg
- 2020, 20(3), pp.269-279
- DOI : 10.13065/jksdh.20200025
- Publisher : Korean Society of Dental Hygiene
- Research Area : Medicine and Pharmacy > Dentistry
- Received : March 18, 2020
- Accepted : April 19, 2020
- Published : June 30, 2020
Su-Yeon Hwang 1, Kim Hae-Young 1, Sunmi Song 1, Eun-Sil Choi 2
1고려대학교
2Gangwon Public Health Policy Institute
Accredited
ABSTRACT
Objectives: Previous studies have reported inconsistent findings in the association between dental diagnostic X-ray exposure and thyroid cancer. This study was a meta-analysis of case–control studies evaluating the association between exposure to dental radiation and the thyroid cancer risk. Methods: We searched the PubMed and EMBASE databases to identify studies on dental radiation and thyroid cancer risks that were published up to September 2018. Quality of studies was assessed using the Newcastle–Ottawa scale. A fixed-effects model was used to estimate pooled odds ratios (ORs) and 95% confidence intervals (CIs) using STATA 14.0. Potential publication biases were evaluated using Egger's test and Begg's funnel plot. Results: From the literature search, we included six case–control studies in this meta-analysis. The meta-analysis using the fixed-effects model found that dental X-ray exposure was associated with 2.34 times increased risk for thyroid cancer (OR=2.34, 95% CI=1.79–3.21). There was no heterogeneity in the data (p=0.662, I2 =0%).
Egger's test showed that there was no publication bias (p=0.532). Conclusions: This meta-analysis confirmed the association of dental X-ray exposure and thyroid cancer risk. The current results underscore the importance of applying safety regulations at dental clinics to protect thyroid glands during dental radiography examinations.
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[journal]
Pellegriti G
/ 2013
/ Worldwide increasing incidence of thyroid cancer: update on epidemiology and risk factors
/ J Cancer Epidemiol
2013
: 965212~
[journal]
Jung CK
/ 2014
/ The increase in thyroid cancer incidence during the last four decades is accompanied by a high frequency of BRAF mutations and a sharp increase in RAS mutations
/ The Journal of Clinical Endocrinology & Metabolism
99(2)
: E276~E285
[book]
Curado MP
/ 2007
/ Cancer incidence in five continents
/ IARC Press, International Agency for Research on Cancer
: 896~
[journal]
Siegel RL
/ 2017
/ Cancer statistics, 2017
/ CA Cancer J Clin
67(1)
: 7~30
[journal]
Joseph KR
/ 2018
/ Multifocality as a prognostic factor in thyroid cancer: A meta-analysis
/ International Journal of Surgery
50
: 121~125
[journal]
Clark OH
/ 1991
/ Thyroid cancer
/ Med Clin North Am
75(1)
: 211~234
[journal]
Bogdanova TI
/ 2006
/ A cohort study of thyroid cancer and other thyroid diseases after the Chornobyl accident: pathology analysis of thyroid cancer cases in Ukraine detected during the first screening (1998-2000)
/ Cancer
107(11)
: 2559~2566
[journal]
Ivanov VK
/ 2012
/ Radiation-epidemiological studies of thyroid cancer incidence in Russia after the Chernobyl accident (estimation of radiation risks, 1991-2008 follow-up period)
/ Radiat Prot Dosimetry
151(3)
: 489~499
[journal]
Nagataki S
/ 1994
/ Thyroid diseases among atomic bomb survivors in Nagasaki
/ JAMA
272(5)
: 364~370
[journal]
Mettler Jr FA
/ 2000
/ CT scanning: patterns of use and dose
/ J Radiol Prot
20(4)
: 353~
[journal]
Schonfeld SJ
/ 2011
/ Medical exposure to radiation and thyroid cancer
/ Clin Oncol
23(4)
: 244~250
[journal]
Neta G
/ 2013
/ A prospective study of medical diagnostic radiography and risk of thyroid cancer
/ Am J Epidemiol
177(8)
: 800~809
[journal]
Mazonakis M
/ 2007
/ Thyroid dose from common head and neck CT examinations in children : is there an excess risk for thyroid cancer induction
/ Eur Radiol
17(5)
: 1352~1357
[journal]
Lintag K
/ 2019
/ Radiation safety practices of dental hygienists in the United States
/ J Dent Hyg
93(4)
: 14~23
[journal]
Claus EB
/ 2012
/ Dental x-rays and risk of meningioma
/ Cancer
118(18)
: 4530~4537
[journal]
Han YY
/ 2012
/ Are frequent dental x-ray examinations associated with increased risk of vestibular schwannoma
/ J Neurosurg
117(Special_Suppl)
: 78~83
[journal]
Horn-Ross PL
/ 1997
/ Environmental factors and the risk of salivary gland cancer
/ Epidemiology
1
: 414~419
[journal]
Memon A
/ 2010
/ Dental x-rays and the risk of thyroid cancer: A case-control study
/ Acta Oncol
49(4)
: 447~453
[journal]
Wingren G
/ 1993
/ Determinants of papillary cancer of the thyroid
/ Am J Epidemiol
138(7)
: 482~491
[journal]
Inskip PD
/ 1995
/ Medical diagnostic x rays and thyroid cancer
/ JNCI : Journal of the National Cancer Institute
87(21)
: 1613~1621
[journal]
Wingren G
/ 1997
/ Diagnostic X-ray exposure and female papillary thyroid cancer:A pooled analysis of two Swedish studies
/ Eur J Cancer Prev
6(6)
: 550~556
[journal]
Hallquist A
/ 1994
/ Medical diagnostic and therapeutic ionizing radiation and the risk for thyroid cancer : A case-control study
/ Eur J Cancer Prev
3(3)
: 259~267
[journal]
Zhang Y
/ 2015
/ Diagnostic radiography exposure increases the risk for thyroid microcarcinoma : A population-based case-control study
/ Eur J Cancer Prev
24(5)
: 439~446
[journal]
Han MA
/ 2018
/ Diagnostic X-ray exposure and thyroid cancer risk : Systematic review and metaanalysis
/ Thyroid
28(2)
: 220~228
[journal]
Stroup DF
/ 2000
/ Meta-analysis of observational studies in epidemiology : a proposal for reporting
/ JAMA
283(15)
: 2008~2012
[journal]
Stang A
/ 2010
/ Critical evaluation of the Newcastle-Ottawa scale for the assessment of the quality of nonrandomized studies in meta-analyses
/ Eur J Epidemiol
25(9)
: 603~605
[journal]
Xu P
/ 2015
/ Exposure to ionizing radiation during dental X-rays is not associated with risk of developing meningioma : A meta-analysis based on seven casecontrol studies
/ PLoS One
10(2)
: e0113210~
[journal]
Ron E
/ 1995
/ Thyroid cancer after exposure to external radiation : a pooled analysis of seven studies
/ Radiat Res
141(3)
: 259~277
[journal]
Ron E
/ 2003
/ Cancer risks from medical radiation
/ Health Phys
85(1)
: 47~59
[journal]
Crane G
/ 2016
/ Radiation shielding in dentistry : an update
/ Aust Dent J
61(3)
: 277~281
[journal]
Hall E
/ 2008
/ Cancer risks from diagnostic radiology
/ Br J Radiol
81(965)
: 362~378
[journal]
Zielinski J
/ 2009
/ Low dose ionizing radiation exposure and cardiovascular disease mortality : cohort study based on Canadian national dose registry of radiation workers
/ Int J Occup Med Environ Health
22(1)
: 27~33
[journal]
한원정
/ 2012
/
Absorbed and effective dose for periapical radiography using portable and wall type dental X-ray machines
/ 대한치과보철학회지
/ 대한치과보철학회
50(3)
: 184~190
[journal]
Hershman JM
/ 2013
/ Repeated dental X-rays without neck shielding predispose to thyroid cancer
/ Clin Thyroidol
25
: 201~202
[journal]
Su-Yeon Hwang
/ 2018
/ Health effects from exposure to dental diagnostic X-ray
/ Environmental Health and Toxicology
/ The Korean Society of Environmental Health and Toxicology
33(4)
: e2018017~