본문 바로가기
  • Home

Effects of antibacterial mouth rinses on multiple oral biofilms model

  • Journal of Korean society of Dental Hygiene
  • Abbr : J Korean Soc Dent Hyg
  • 2023, 23(4), pp.209-218
  • DOI : 10.13065/jksdh.20230023
  • Publisher : Korean Society of Dental Hygiene
  • Research Area : Medicine and Pharmacy > Dentistry
  • Received : June 5, 2023
  • Accepted : July 19, 2023
  • Published : August 30, 2023

Soo-Kyung Jun 1 Young-Suk Choi 2

1Department of Dental Hygiene, Hanseo University
2Department of Dental Hygiene, Shinsung University

Accredited

ABSTRACT

Objectives: To confirm the antibacterial effects of each mouth rinse on multiple oral biofilms in vitro. Methods: The antibacterial effects of different mouth rinses were examined by ATP and counted colony forming units (CFU). Preformed oral biofilms on saliva coated hydroxyapatite (sHA) disks were treated with essential oil and saline; then, the multiple oral biofilms were observed by Scanning electron microscope (SEM). RNA sequencing analysis was performed on total RNA isolated from old biofilms of P. intermedia ATCC 49046. Results: In the CFU measured result compared to controls, preformed multiple oral biofilms were reduced from a low of 39.0% to 95.7% (p <0.05). The size of bacterial cells changed after treatment with the essential oil, and some of the cells ruptured into small pieces of cell debris. Gene expression in P. intermedia ATCC 49046 significantly altered in RNA transcribed and protein translated genes after exposure to essential oil. Conclusions: Mouth rinse solutions with different ingredients had different antibacterial effects and may alter surface structure and gene expression as determined by RNA sequencing.

Citation status

* References for papers published after 2022 are currently being built.