@article{ART003196779},
author={Cho Mu-Yeol and Hwang Ji-Young and Eom Je-Hyun and Choi Eun-Mi and Lee Jeong-Hoo and Kim Yeon-Jin and Hwang Ju-Young and Kim Hye-Sung and Hwang In-Seong},
title={Effects of non-surgical periodontal treatment with probiotic supplementation on metabolic dysfunction in patients with periodontitis: a retrospective study},
journal={Journal of Korean society of Dental Hygiene},
issn={2287-1705},
year={2025},
volume={25},
number={2},
pages={101-111},
doi={10.13065/jksdh.2025.25.2.2}
TY - JOUR
AU - Cho Mu-Yeol
AU - Hwang Ji-Young
AU - Eom Je-Hyun
AU - Choi Eun-Mi
AU - Lee Jeong-Hoo
AU - Kim Yeon-Jin
AU - Hwang Ju-Young
AU - Kim Hye-Sung
AU - Hwang In-Seong
TI - Effects of non-surgical periodontal treatment with probiotic supplementation on metabolic dysfunction in patients with periodontitis: a retrospective study
JO - Journal of Korean society of Dental Hygiene
PY - 2025
VL - 25
IS - 2
PB - Korean Society of Dental Hygiene
SP - 101
EP - 111
SN - 2287-1705
AB - Objectives: Probiotic supplementation, integrated into routine oral care, may improve periodontal status and metabolic function. In this retrospective longitudinal study, we evaluated the efficacy of probiotics added to non-surgical periodontal treatment (NSPT) in reducing the burden of oral pathogens and improving metabolic dysfunction. Methods: Twenty outpatients with chronic periodontitis and at least one metabolic abnormality underwent NSPT with daily probiotic supplementation for 12 weeks. Baseline and post-intervention assessments included clinical indices, blood pressure, and blood biomarkers (HbA1c, fasting glucose, and lipid profiles), with analysis of oral pathogens using qPCR. Results: Among the 13 eligible participants, probiotics with NSPT resulted in significant reductions in HbA1c (-0.3%, p<0.001), and systolic blood pressure (-9.6 mmHg, p<0.001), and Tannerella forsythia (p<0.05) levels, along with decreasing trends in other pathogens. However, no significant changes were noted in periodontal indices, including probing pocket depth and bleeding on probing, nor in lipid profiles. Conclusions: These f indings suggest that probiotic supplementation with NSPT may improve glycemic control and systolic blood pressure but may have a limited effect on periodontal indices, warranting larger trials to confirm its potential.
KW - Blood glucose;Blood pressure;Periodontal therapy;Periodontitis;Probiotics
DO - 10.13065/jksdh.2025.25.2.2
ER -
Cho Mu-Yeol, Hwang Ji-Young, Eom Je-Hyun, Choi Eun-Mi, Lee Jeong-Hoo, Kim Yeon-Jin, Hwang Ju-Young, Kim Hye-Sung and Hwang In-Seong. (2025). Effects of non-surgical periodontal treatment with probiotic supplementation on metabolic dysfunction in patients with periodontitis: a retrospective study. Journal of Korean society of Dental Hygiene, 25(2), 101-111.
Cho Mu-Yeol, Hwang Ji-Young, Eom Je-Hyun, Choi Eun-Mi, Lee Jeong-Hoo, Kim Yeon-Jin, Hwang Ju-Young, Kim Hye-Sung and Hwang In-Seong. 2025, "Effects of non-surgical periodontal treatment with probiotic supplementation on metabolic dysfunction in patients with periodontitis: a retrospective study", Journal of Korean society of Dental Hygiene, vol.25, no.2 pp.101-111. Available from: doi:10.13065/jksdh.2025.25.2.2
Cho Mu-Yeol, Hwang Ji-Young, Eom Je-Hyun, Choi Eun-Mi, Lee Jeong-Hoo, Kim Yeon-Jin, Hwang Ju-Young, Kim Hye-Sung, Hwang In-Seong "Effects of non-surgical periodontal treatment with probiotic supplementation on metabolic dysfunction in patients with periodontitis: a retrospective study" Journal of Korean society of Dental Hygiene 25.2 pp.101-111 (2025) : 101.
Cho Mu-Yeol, Hwang Ji-Young, Eom Je-Hyun, Choi Eun-Mi, Lee Jeong-Hoo, Kim Yeon-Jin, Hwang Ju-Young, Kim Hye-Sung, Hwang In-Seong. Effects of non-surgical periodontal treatment with probiotic supplementation on metabolic dysfunction in patients with periodontitis: a retrospective study. 2025; 25(2), 101-111. Available from: doi:10.13065/jksdh.2025.25.2.2
Cho Mu-Yeol, Hwang Ji-Young, Eom Je-Hyun, Choi Eun-Mi, Lee Jeong-Hoo, Kim Yeon-Jin, Hwang Ju-Young, Kim Hye-Sung and Hwang In-Seong. "Effects of non-surgical periodontal treatment with probiotic supplementation on metabolic dysfunction in patients with periodontitis: a retrospective study" Journal of Korean society of Dental Hygiene 25, no.2 (2025) : 101-111.doi: 10.13065/jksdh.2025.25.2.2
Cho Mu-Yeol; Hwang Ji-Young; Eom Je-Hyun; Choi Eun-Mi; Lee Jeong-Hoo; Kim Yeon-Jin; Hwang Ju-Young; Kim Hye-Sung; Hwang In-Seong. Effects of non-surgical periodontal treatment with probiotic supplementation on metabolic dysfunction in patients with periodontitis: a retrospective study. Journal of Korean society of Dental Hygiene, 25(2), 101-111. doi: 10.13065/jksdh.2025.25.2.2
Cho Mu-Yeol; Hwang Ji-Young; Eom Je-Hyun; Choi Eun-Mi; Lee Jeong-Hoo; Kim Yeon-Jin; Hwang Ju-Young; Kim Hye-Sung; Hwang In-Seong. Effects of non-surgical periodontal treatment with probiotic supplementation on metabolic dysfunction in patients with periodontitis: a retrospective study. Journal of Korean society of Dental Hygiene. 2025; 25(2) 101-111. doi: 10.13065/jksdh.2025.25.2.2
Cho Mu-Yeol, Hwang Ji-Young, Eom Je-Hyun, Choi Eun-Mi, Lee Jeong-Hoo, Kim Yeon-Jin, Hwang Ju-Young, Kim Hye-Sung, Hwang In-Seong. Effects of non-surgical periodontal treatment with probiotic supplementation on metabolic dysfunction in patients with periodontitis: a retrospective study. 2025; 25(2), 101-111. Available from: doi:10.13065/jksdh.2025.25.2.2
Cho Mu-Yeol, Hwang Ji-Young, Eom Je-Hyun, Choi Eun-Mi, Lee Jeong-Hoo, Kim Yeon-Jin, Hwang Ju-Young, Kim Hye-Sung and Hwang In-Seong. "Effects of non-surgical periodontal treatment with probiotic supplementation on metabolic dysfunction in patients with periodontitis: a retrospective study" Journal of Korean society of Dental Hygiene 25, no.2 (2025) : 101-111.doi: 10.13065/jksdh.2025.25.2.2
