Journal of Environmental Impact Assessment 2023 KCI Impact Factor : 0.51
-
pISSN : 1225-7184
- https://journal.kci.go.kr/kseia
KJCKorea
Journal Central
Exposure and Risk Assessments of Multimedia of Arsenic in the Environment
- Journal of Environmental Impact Assessment
- Abbr : J EIA
- 2019, 28(2), pp.152-168
- Publisher : Korean Society Of Environmental Impact Assessment
- Research Area : Engineering > Environmental Engineering
- Published : April 30, 2019
Ki_Tae Sim 1, 김동훈 1, Jae-woo Lee 1, Chae-Hong Lee 1, SoYeon Park 1, Kwang-Seol Seok 2, Young-Hee Kim 2
1국립환경과학원
2국립환경과학원 화학물질연구과
Accredited
ABSTRACT
The element arsenic, which is abundant in the Earth’s crust, is used for various industrial purposes including materials for disease treatment and household goods. Various human activities, such as the disposal of soil waste, metal mining and smelting, and combustion of fossil fuels, have caused the pollution ofthe environment with arsenic.Recently, guidelines for arsenic in rice have been adopted by the Korean ministry of food and drug safety to prevent health risks based on rice consumption. Because of the exposure to arsenic and its accumulation in the human body through various channels, such as air inhalation, skin contact, ingestion of drinking water, and food consumption, integrated multimedia risk assessment is required to adopt appropriate risk management policies. Therefore, integrated human health risk assessment was carried outin this study using integrated exposure assessment based on multimedia (e.g., air, water, and soil) and multi-route (e.g., oral, inhalation, and dermal) scenarios.
The results show that oral uptake via drinking wateris the most common pathway of arsenic into the human body, accounting for 57%-96% of the total arsenic exposure. Among various age groups, the highest exposures to arsenic were observed in infants because the body weight of infants is low and the surface areas ofinfant bodies are large. Based on the results ofthe exposure assessment,the cancer and non-cancer risks were calculated. The cancer risk for CTE and RME is in the range of 2.3E-05 to 6.7E-05 and thus is negligible because it does not exceed the cancer probability of 1.0E-04 for all age groups. On the other hand, the cancer risk for RME varies from 6.4E-05 to 1.8E-04 and from 1.3E-04 to 1.8E-04 for infants and preschool children, exceeding the excess cancerrisk of 1.0E-04. The non-cancerrisks range from 5.4E-02 to 1.9E-01 and from 1.5E-01 to 6.8E-01, respectively. They do not exceed the hazard index 1 for all scenarios and all ages.
Statistics
-
1,120 Viewed
-
345 Downloaded
Tools
Issue List
Citation status
* References for papers published after 2023 are currently being built.
[other]
American Conference of Governmental Industrial Hygienists
/ 2004
/ Arsenic. Threshold limit values for chemical substances and physical agents and biological exposure indices
/ American Conference of Governmental Industrial Hygienists
[other]
Agency for Toxic Substances and Disease Registry
/ 1999
/ Toxicological profile for Arsenic;draft for public comment
/ US Public Health Service
[other]
Agency for Toxic Substances and Disease Registry
/ 2000
/ Toxicological profile for Arsenic;draft for public comment
/ US Public Health Service
[other]
Agency for Toxic Substances and Disease Registry
/ 2007
/ Toxicological profile for Arsenic (update); draft for public comment
/ US Public Health service
[journal]
Ahmad SA
/ 1999
/ Arsenicosis : sex differentials
/ J Prec Soc Med
18
: 35~40
[journal]
Ahmed KM
/ 2004
/ Arsenic enrichment in groundwater of the alluvial aquifer in Bangledesh: an overview
/ Appl. Geochem
19
: 181~200
[journal]
Ahsan H
/ 2006
/ Arsenic exposure from drinking water and risk of premaligmant skin lesions in Bangladesh : baseline results from the health effects of arsenic longitudinal study
/ American Journal of Epidemiology
163
: 1138~1148
[book]
Azcue JM
/ 1994
/ Arsenic in the Environment Part I: Cycling and Characterization
: 1~15
[journal]
Bickley LK
/ 1989
/ Chronic arsenicism with vitiligo, hyperthyroidism and cancer
/ New Jersey Medicine. The Journal of the Medical Society of New Jersey
86
: 377~380
[journal]
Buchet JP
/ 1981
/ Comparison of the urinary excretion of arsenic metabolites after a single oral dose of sodium arsenite, monomethylarsonate, or dimethylarsinate in man
/ Int Arch Occup Environ Health
48
: 71~79
[other]
Canada
/ 2015
/ Fertilizers Regulations
[journal]
Cappuyns V
/ 2002
/ Arsenic pollution at the industrial site of Reppel-Bocholt (north Belgium)
/ Sci Tot Environ
295
: 217~240
[journal]
Charlet L
/ 2001
/ Risk of arsenic transfer to a semiconfined aquifer and the effect of water level fluctuation in North Mortagne france at a former industrial site
/ Sci Tot Environ
277
: 133~147
[report]
Tokyo University
/ 2010
/ Japanese arsenic exposure and health risk
[other]
European Chemicals Agency
/ 2015
/ European chemical substances information system
[journal]
Enterline PE
/ 1982
/ Cancer among workers exposed to arsenic and other substances in a copper smelter
/ Am J Epidemiol
116
: 895~911
[journal]
European Food Safety Authority
/ 2009
/ SCIENTIFIC OPINION Cadmium in food, Scientific opinion of the panel on contaminants in the food chain
/ The EFSA Journal
980
: 1~139
[book]
Hamilton, A
/ 1998
/ Hamilton and hardy’s industrial toxicology
/ Mosby
[other]
Health Canada
/ 2015
/ List of prohibited and restricted cosmetic ingredients (The cosmetic ingredient “Hotlist”)
[book]
International Agency for Research on Cancer
/ 2012
/ Monographs on the evaluation of carcinogenic risks to humans. A review of human carcinogens: Arsenic, metals, fibers and dusts vol. 100C
[journal]
Jarup DM
/ 1991
/ Arsenic exposure, smoking and lung cancer in smelter workers a case-control study
/ Am J Epidemiol
134
: 545~551
[journal]
전준민
/ 2010
/
Health Risk Assessment of Heavy Metals in PM2.5 in Industrial Areas
/ 한국환경보건학회지
/ 한국환경보건학회
36(4)
: 294~305
[journal]
Juillot F
/ 1999
/ Remobilization of arsenic from buried wastes at an industrial site : mineralogical and geochemical control
/ Appl Geochem
14
: 1031~1048
[report]
Korea Environment Corporation
/ 2010
/ A survey and management measures for indoor activities in children
[journal]
김호현
/ 2012
/
Health risk assessment of trace elements exposure through multi-pathways in children's facilities : focused on elementary-schools and academies
/ 한국실내환경학회지
/ 한국실내환경학회
9(3)
: 213~228
[other]
Korea health industry development agency
/ 2015
/ National nutrition statistics for 2013 (II)
[journal]
김재희
/ 2009
/
Assessment of Physical Activity, Activity Coefficient of Preschool Children and Actual Condition of Daycare Center Outdoor Play
/ 대한지역사회영양학회지
/ 대한지역사회영양학회
14(6)
: 777~788
[journal]
Kligerman AD
/ 2003
/ Methylated trivalent arsenicals as candidate ultimate genotoxic forms of arsenic:induction of chromosomal mutations but not gene mutations
/ Environ Mol Mutagen
42
: 192~205
[journal]
김명진
/ 2003
/
Vertical Distribution and Mobility of Arsenic and Heavy Metals in Mine Tailings and Nearby Paddy Fields
/ 대한환경공학회지
/ 대한환경공학회
25(5)
: 544~553
[journal]
손부순
/ 2007
/
Estimation of Total Exposure to Benzene, Toluene and Xylene by？ Microenvironmental Measurements for Iron Mill Workers
/ 한국환경보건학회지
/ 한국환경보건학회
33(5)
: 359~364
[journal]
김원일
/ 2008
/
Long-term monitoring of heavy metal contents in paddy soils
/ 한국토양비료학회지(Korean Journal of Soil Science and Fertilizer)
/ 한국토양비료학회
41(3)
: 190~198
[journal]
Lee AM
/ 1969
/ Arsenic and respiratory cancer in man : an occupational study
/ J Natl Cancer Inst
42
: 1045~1052
[journal]
이해근
/ 2015
/
Occurrence of Arsenic, Strontium, and Selenium in Drinking Water in Kyungpook Province, Korea, in Relation to Geologic Formations
/ 한국지반환경공학회 논문집
/ 한국지반환경공학회
16(1)
: 55~60
[journal]
이진수
/ 2004
/
Human Risk Assessment of Toxic Heavy Metals Around Abandoned Metal Mine Sites
/ 자원환경지질
/ 대한자원환경지질학회
37(1)
: 73~86
[journal]
이진수
/ 2005
/
Risk Assessment of Arsenic by Human Exposure of Contaminated Soil, Groundwater and Rice Grain
/ 자원환경지질
/ 대한자원환경지질학회
38(5)
: 535~545
[journal]
이상우
/ 2015
/
Human Risk Assessment of Arsenic and Heavy Metal Contamination and Estimation of Remediation Concentration within Abandoned Metal Mine Area
/ 광물과 암석
/ 한국광물학회
28(4)
: 309~323
[journal]
이원영
/ 2014
/
A study on health risk assessment of volatile organic compounds in child-care center
/ 실내환경 및 냄새 학회지
/ 한국냄새환경학회
13(4)
: 297~305
[journal]
Levin-Scherz JK
/ 1987
/ Acute arsenic ingestion
/ Ann Emerg Med
16
: 702~704
[journal]
임현철
/ 2004
/
The Study on the Quality of Natural Mineral Water
/ 지구물리
/ 대한지구물리학회
7(1)
: 41~49
[journal]
Lim YR
/ 2000
/ Determination of total arsenic in drinking water by inductively coupled plasma-mass spectrometry
/ Analytical Science & Technology
13(4)
: 423~427
[journal]
Mass MJ
/ 2001
/ Methylated trivalent arsenic species are genotoxic
/ Chem Res Toxicol
14
: 355~361
[journal]
Meent D. Van de
/ 1995
/ A modeling procedure to evaluate the coherence of independently derived environmental quality objectives for air, water and soil
/ Environmental Toxicology and Chemistry
14
: 177~186
[report]
Ministry of Environment
/ 2006
/ Exposure assessment and non-cancer risk assessment of domestic drinking water in arsenic
[other]
Ministry of Environment
/ 2007
/ Korea exposure factor handbook
[report]
Ministry of Environment
/ 2009
/ A study on the health influential factors in healthy area
[report]
Ministry of Environment
/ 2009
/ A survey on pollution situation of hazardous substances in children’s activity space for risk assessment management
[report]
Ministry of Environment
/ 2010
/ Risk assessment and infrastructure construction of environmental harmful factors
[other]
Ministry of Environment
/ 2015
/ Heavy metals network (As in PM10)
[other]
Ministry of Environment
/ 2016
/ Notice No. 2016-178. Chemical management act
[other]
Ministry of Environment
/ 2016
/ Guidance on procedures and methods for risk assessment of environmental hazard factors. No. 585
[other]
Ministry of Environment
/ 2017
/ Basic law on environmental policy law No. 14532. 2017.1.17
[other]
Ministry of Environment
/ 2017
/ Drinking water act law No. 14532. 2017.1.17
[report]
Ministry of Employment and Labor
/ 2016
/ Business workforce report
[report]
Ministry of Employment and Labor
/ 2017
/ Business workforce report
[other]
Ministry of Food and Drug Safety
/ 2016
/ Notice No. 2016-101. Standards and specification for food
[other]
Ministry of Health and Welfare
/ 2011
/ National health statistics
[other]
Ministry of Health and Welfare
/ 2012
/ National health statistics
[other]
Ministry of Health and Welfare
/ 2013
/ National health statistics
[other]
Ministry of Health and Welfare
/ 2015
/ National childcare survey
[other]
Ministry of the Interior and Safety
/ 2016
/ Resident registration demographic data
[other]
Ministry of Education
/ 2015
/ Elementary and secondary education law. Presidential Decree No. 28112
[other]
Ministry of Education
/ 2015
/ Infant education law. Presidential Decree No. 28112
[report]
National Institute of Environmental Research
/ 2008
/ A study on risk assessment and establishment of risk management plan
[report]
National Institute of Environmental Research
/ 2005
/ A study on the evaluation and establishment of soil pollution standards (II)
[report]
National Institute of Environmental Research
/ 2010
/ A study on the risk assessment and the establishment of infrastructure for environmental hazardous factors
[report]
National Institute of Environmental Research
/ 2012
/ A study on the environmental safety management of children’s activity space
[other]
National Institute of Environmental Research
/ 2014
/ Notice No. 2014-48. Regulation on specific methods of chemical risk assessment
[report]
National Institute of Environmental Research
/ 2014
/ Multi-media and multi-pathway aggregate risk assessment (IV)
[other]
National Institute of Environmental Research
/ 2016
/ Children exposure factor handbook
[report]
National Institute of Environmental Research
/ 2016
/ A survey on soil prediction and soil contamination in 2015
[other]
National Institute for Occupational Safety and Health
/ 2005
/ Arsenic. NIOSH pocket guide to chemical hazards
/ Centers for Disease Control and Prevention
[report]
National Institute of Technology and Evaluation
/ 2007
/ Summary of initial risk assessment report_arsenic and its inorganic compounds
[book]
National Research Council Canada
/ 1978
/ Effects of arsenic in the Canadian environment
: 1~249
[confproc]
Oline S
/ 1998
/ Aggregate assessment
/ ILSI Workshop Report
[journal]
박은정
/ 2005
/
Health risk assessment of health metals in fine particles collected in seoul metropolitan area.
/ 환경독성보건학회지
/ 환경독성보건학회
20(2)
: 179~186
[journal]
박명규
/ 2016
/
Health risk assessment for heavy metal exposure in the living environment
/ 실내환경 및 냄새 학회지
/ 한국냄새환경학회
15(4)
: 392~400
[journal]
Quatrehomme G
/ 1992
/ Acute arsenic intoxication : forensic and toxicologic aspects(an observation)
/ J Forensic Sci
37
: 1163~1171
[report]
Netherlands National Institute for Public Health and the Environment (RIVM)
/ 2001
/ Reevaluation of human-toxicological maximum permissible risk level
[journal]
Scheuplein R
/ 2002
/ Differential sensitivity of children and adults to chemical toxicity : I. Biological basis
/ Regul Toxicol Pharmacol
35(3)
: 429~447
[journal]
서정관
/ 2013
/
Aggregate Risk Assessment on Xylene and Ethylbenzene
/ 한국환경과학회지
/ 한국환경과학회
22(2)
: 163~171
[journal]
Shin DS
/ 1994
/ Carcinogenic risk assessment of heavy metals in suspended particulates of Seoul
/ Korean Society for Atmospheric Environment
10(2)
: 105~115
[journal]
Simeonova PP
/ 2003
/ Arsenic exposure accelerates atherogenesis in apolipoprotein E(-/-)mice
/ Environ Health Perspect
111
: 1744~1748
[journal]
Smedley PL
/ 2002
/ A review of the source, behavior and distribution of arsenic in natural waters
/ Appl Geochem
17
: 517~568
[book]
Sofia G
/ 2008
/ Water Framework Directive:Defining the Ecological Quality Status in Transitional and Coastal Waters, Sustainable use and development of watersheds
/ Springer Netherlands
[journal]
Tokudome S
/ 1976
/ A cohort study on mortality from cancer and other causes among workers at a metal refinery
/ Int J Cancer
17
: 310~317
[journal]
Vahter M
/ 1982
/ Metabolism of 74Aslabeled trivalent and pentavalent inorganic arsenic in mice
/ Environ Res
21
: 446~457
[journal]
Vantroyen B
/ 2004
/ Survival after a lethal dose of arsenic trioxide
/ Journal of Toxicology. Clinical Toxicology
42
: 889~895
[other]
VDEQ
/ 2017
/ Voluntary Remediation Program Risk Assessment Guidance
/ Virginia Department of Environmental Quality
[journal]
Welch AH
/ 2000
/ Arsenic in ground water of The United States : Occurrence and geochemistry
/ Ground Water
38(4)
: 589~604
[other]
WHO
/ 1996
/ Guidelines for drinking-water quality, 2th edition
[journal]
Woolson EA
/ 1975
/ The persistence and chemical distribution of arsenic acid in three soil
/ Journal of Agricultural Food Chemical
23
: 677~681
[journal]
Uede K
/ 2003
/ Skin manifestations in acute arsenic poisoning from the Wakayama curry-poisoning incident
/ Br J Dermatol
149
: 757~762
[other]
US EPA
/ 1986
/ Guidelines for the Health Risk Assessments of Chemical Mixtures, 51Federal Register 34014
[other]
US EPA
/ 1990
/ Guidance for data useability in risk assessment
[other]
US EPA
/ 1993
/ Integrated Risk Information System-Arsenic (Inorganic)
[other]
US EPA
/ 1998
/ Arsenic, inorganic (CASRN 7440-38-2)
[other]
US EPA
/ 2004
/ Risk assessment guidance for superfund volume: Human health evaluation manual (Part A)
[other]
US EPA
/ 2011
/ Exposure factors handbook
[other]
US EPA
/ 2012
/ Resource conservation and recovery act, 40CFR 261. 24-toxicity characteristic
[journal]
양경
/ 2014
/
Determination of Human Health Risk Incorporated with Arsenic Bioaccessibility and Remediation Goals at the Former Janghang Smelter Site
/ 지하수토양환경
/ 한국지하수토양환경학회
19(4)
: 52~61
[journal]
양지연
/ 2011
/
Health risk assessment of trace elements exposure through multi pathways in children's facilities
/ 한국실내환경학회지
/ 한국실내환경학회
8(1)
: 20~38
[journal]
Zaldivar R
/ 1977
/ Environmental and clinical investigations on endemic chronic arsenic poisoning in infants and children
/ Zentrabl Bakt Hyg I Abt Orig B
165(2)
: 226~234