@article{ART002708639},
author={Seo Yong-bae and Jeong-Mo Song},
title={Effecs of Soyangin Indongdeungjikolpitang on the Complication of Diabetes},
journal={Journal of Sasang Constitution and Immune Medicine},
issn={1226-4075},
year={2000},
volume={12},
number={1},
pages={186-200}
TY - JOUR
AU - Seo Yong-bae
AU - Jeong-Mo Song
TI - Effecs of Soyangin Indongdeungjikolpitang on the Complication of Diabetes
JO - Journal of Sasang Constitution and Immune Medicine
PY - 2000
VL - 12
IS - 1
PB - The Society of Sasang Constitution and Immune Medicine
SP - 186
EP - 200
SN - 1226-4075
AB - The purpose of this research was to investigate the effects of Indongdeungjikolpitang water extract(IJTE) on the complication of diabetes. IJTE did not affect the level of blood glucose in alloxan- or streptozotocin-induced hyperglycemic mice, but inhibited the motility of gastrointestine. IJTE inhibited the writhing syndrome induced by acetic acid, the permeability of evans blue into peritoneal cavity induced by acetic acid, the paw edema induced by histamine, and the formation of cotton pellet granuloma. IJTE increased the cell viability of thymocytes and splenocytes. IJTE decreased the release of γ-interferone(γ-IFN) and interleukin-2(IL-2), but did not affect the release of interleukin-4(IL-4) from murine thymocytes. IJTE increased the release of IL-4 and decreased the release of tumor necrosis factor-α(TNF-α) and interleukin-1β(IL-1β), but did not affect of γ-IFN and IL-2 from murine splenocytes. IJTE decreased the release of TNF-α and IL-1β from murine peritoneal macrophages. IJTE decreased the production of niric oxide(NO) from murine peritioneal macrophages and increased the phagocytic activity of murine peritoneal macrophages. These results suggest that IJTE has an anti-inflammatory action via the inhibition of TNF-α, IL-1β and NO production from immune cells.
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Seo Yong-bae and Jeong-Mo Song. (2000). Effecs of Soyangin Indongdeungjikolpitang on the Complication of Diabetes. Journal of Sasang Constitution and Immune Medicine, 12(1), 186-200.
Seo Yong-bae and Jeong-Mo Song. 2000, "Effecs of Soyangin Indongdeungjikolpitang on the Complication of Diabetes", Journal of Sasang Constitution and Immune Medicine, vol.12, no.1 pp.186-200.
Seo Yong-bae, Jeong-Mo Song "Effecs of Soyangin Indongdeungjikolpitang on the Complication of Diabetes" Journal of Sasang Constitution and Immune Medicine 12.1 pp.186-200 (2000) : 186.
Seo Yong-bae, Jeong-Mo Song. Effecs of Soyangin Indongdeungjikolpitang on the Complication of Diabetes. 2000; 12(1), 186-200.
Seo Yong-bae and Jeong-Mo Song. "Effecs of Soyangin Indongdeungjikolpitang on the Complication of Diabetes" Journal of Sasang Constitution and Immune Medicine 12, no.1 (2000) : 186-200.
Seo Yong-bae; Jeong-Mo Song. Effecs of Soyangin Indongdeungjikolpitang on the Complication of Diabetes. Journal of Sasang Constitution and Immune Medicine, 12(1), 186-200.
Seo Yong-bae; Jeong-Mo Song. Effecs of Soyangin Indongdeungjikolpitang on the Complication of Diabetes. Journal of Sasang Constitution and Immune Medicine. 2000; 12(1) 186-200.
Seo Yong-bae, Jeong-Mo Song. Effecs of Soyangin Indongdeungjikolpitang on the Complication of Diabetes. 2000; 12(1), 186-200.
Seo Yong-bae and Jeong-Mo Song. "Effecs of Soyangin Indongdeungjikolpitang on the Complication of Diabetes" Journal of Sasang Constitution and Immune Medicine 12, no.1 (2000) : 186-200.
