@article{ART002708910},
author={Ch'oi Yei-kwen and kim kyung yo},
title={Studies on the Regulatory Effect of Cytokine Production in Patients with Cerebral Infarction by Yuldahansotang},
journal={Journal of Sasang Constitutional Medicine},
issn={1226-4075},
year={2000},
volume={12},
number={1},
pages={201-215}
TY - JOUR
AU - Ch'oi Yei-kwen
AU - kim kyung yo
TI - Studies on the Regulatory Effect of Cytokine Production in Patients with Cerebral Infarction by Yuldahansotang
JO - Journal of Sasang Constitutional Medicine
PY - 2000
VL - 12
IS - 1
PB - The Society Of Sasang Constitutional Medicine
SP - 201
EP - 215
SN - 1226-4075
AB - 1. Background and Purpose According to Sasang constitutional medicine, Yuldahansotang(YHT) is a useful prescription for Teaumin patients with a variety of neurologic disorders. Then, I investigated about certain relationships between the effect of YHT and the changes of immune system, especially cytokine network.
2. Methods We studied 8 Taeumin patients with Cerbral infarction. They were treated with YHT in constitutional clinic of Wonkwang Kwagnju Oriental Hospital. We investigated the changes of cytokine network of them. We also investigated cytokine release by lipopolysaccharide- activated peripheral blood mononuclear cells from healthy Taeumin controls.
3. Results The mean interleukin (IL)-2 plasma levels were slightly lower in the plasma of patients than in normal group, whereas the mean IL-4, IL-6 and IgE levels were significantly higher. But there were no significant differences in interferon-γ(IFN-γ) levels between each group.
After administration of YHT for two to four weeks, plasma levels of IFN-γ and IL-2 derived from T helper (Th) 1 cells were elevated significantly, whereas plasma levels of IL-4 and IL-6 derived from Th2 cells were reduced significantly. Plasma levels of IgE were reduced significantly, too. During the period of YHT administration, other adverse effects are not shown.
It is increased significantly to Cytokine release by lipopolysaccharide -activated peripheral blood mononuclear cells from healthy Taeumin controls. And the release of IFN-γ, IL-2 and IL-6 was progressively decreased in the plasma treated with YHT. It shows regulatory effects of YHT to cytokine production.
KW - Sasang constitution;Yuldahansotang;Taeumim;Cerebral infarction;Cytokine
DO -
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ER -
Ch'oi Yei-kwen and kim kyung yo. (2000). Studies on the Regulatory Effect of Cytokine Production in Patients with Cerebral Infarction by Yuldahansotang. Journal of Sasang Constitutional Medicine, 12(1), 201-215.
Ch'oi Yei-kwen and kim kyung yo. 2000, "Studies on the Regulatory Effect of Cytokine Production in Patients with Cerebral Infarction by Yuldahansotang", Journal of Sasang Constitutional Medicine, vol.12, no.1 pp.201-215.
Ch'oi Yei-kwen, kim kyung yo "Studies on the Regulatory Effect of Cytokine Production in Patients with Cerebral Infarction by Yuldahansotang" Journal of Sasang Constitutional Medicine 12.1 pp.201-215 (2000) : 201.
Ch'oi Yei-kwen, kim kyung yo. Studies on the Regulatory Effect of Cytokine Production in Patients with Cerebral Infarction by Yuldahansotang. 2000; 12(1), 201-215.
Ch'oi Yei-kwen and kim kyung yo. "Studies on the Regulatory Effect of Cytokine Production in Patients with Cerebral Infarction by Yuldahansotang" Journal of Sasang Constitutional Medicine 12, no.1 (2000) : 201-215.
Ch'oi Yei-kwen; kim kyung yo. Studies on the Regulatory Effect of Cytokine Production in Patients with Cerebral Infarction by Yuldahansotang. Journal of Sasang Constitutional Medicine, 12(1), 201-215.
Ch'oi Yei-kwen; kim kyung yo. Studies on the Regulatory Effect of Cytokine Production in Patients with Cerebral Infarction by Yuldahansotang. Journal of Sasang Constitutional Medicine. 2000; 12(1) 201-215.
Ch'oi Yei-kwen, kim kyung yo. Studies on the Regulatory Effect of Cytokine Production in Patients with Cerebral Infarction by Yuldahansotang. 2000; 12(1), 201-215.
Ch'oi Yei-kwen and kim kyung yo. "Studies on the Regulatory Effect of Cytokine Production in Patients with Cerebral Infarction by Yuldahansotang" Journal of Sasang Constitutional Medicine 12, no.1 (2000) : 201-215.
