@article{ART002708911},
author={Park Jae-hyung and kim kyung yo},
title={Effect of Taeumin Chungsimyoinjatang Extract on Blood Pressure and Regional Cerebral Blood Flow in Rats},
journal={Journal of Sasang Constitution and Immune Medicine},
issn={1226-4075},
year={2000},
volume={12},
number={1},
pages={216-227}
TY - JOUR
AU - Park Jae-hyung
AU - kim kyung yo
TI - Effect of Taeumin Chungsimyoinjatang Extract on Blood Pressure and Regional Cerebral Blood Flow in Rats
JO - Journal of Sasang Constitution and Immune Medicine
PY - 2000
VL - 12
IS - 1
PB - The Society of Sasang Constitution and Immune Medicine
SP - 216
EP - 227
SN - 1226-4075
AB - 1. Purpose For many years, Taeumin Chungsimyoinjatang(太陰人 淸心蓮子湯, CS) has been used in Sasang(四象) constitutional medicine as a therapeutic agent for cerebral disease. The effects of CS on the vascular system is not well-known. The purpose of this study is to make it clear the effects of SJ and composing drugs on blood pressure(BP) and regional cerebral blood flow(rCBF).
2. Method We measured BP with Pressure Transducer, rCBF with Laser-Doppler flowmeter. Propranolol and methylene blue were used to determine the mechanisms of CS effects.
3. Results and Conclusion BP was not affected by CS in rats, and rCBF was significantly increased by CS in rats. rCBF was increased by Nelumbinis Semen(蓮于肉), Ophiopogonis Radix(麥門冬), Asparagi Radix(天門冬), Polygalae Radix(遠志), Zizyphi Spinosae Semen(酸棗仁), Longnae Arillus(龍眼肉), Raphani Semen, Chrysanthemi Flos(甘菊) in rats. The increase of rCBF is mediated by adrenergic β- receptor and guanylyl cyclase which is enzyme producing cyclic GMP.
KW - Taeumin;Chungsimyoinjatang;blood pressure;regional cerebral blood flow
DO -
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Park Jae-hyung and kim kyung yo. (2000). Effect of Taeumin Chungsimyoinjatang Extract on Blood Pressure and Regional Cerebral Blood Flow in Rats. Journal of Sasang Constitution and Immune Medicine, 12(1), 216-227.
Park Jae-hyung and kim kyung yo. 2000, "Effect of Taeumin Chungsimyoinjatang Extract on Blood Pressure and Regional Cerebral Blood Flow in Rats", Journal of Sasang Constitution and Immune Medicine, vol.12, no.1 pp.216-227.
Park Jae-hyung, kim kyung yo "Effect of Taeumin Chungsimyoinjatang Extract on Blood Pressure and Regional Cerebral Blood Flow in Rats" Journal of Sasang Constitution and Immune Medicine 12.1 pp.216-227 (2000) : 216.
Park Jae-hyung, kim kyung yo. Effect of Taeumin Chungsimyoinjatang Extract on Blood Pressure and Regional Cerebral Blood Flow in Rats. 2000; 12(1), 216-227.
Park Jae-hyung and kim kyung yo. "Effect of Taeumin Chungsimyoinjatang Extract on Blood Pressure and Regional Cerebral Blood Flow in Rats" Journal of Sasang Constitution and Immune Medicine 12, no.1 (2000) : 216-227.
Park Jae-hyung; kim kyung yo. Effect of Taeumin Chungsimyoinjatang Extract on Blood Pressure and Regional Cerebral Blood Flow in Rats. Journal of Sasang Constitution and Immune Medicine, 12(1), 216-227.
Park Jae-hyung; kim kyung yo. Effect of Taeumin Chungsimyoinjatang Extract on Blood Pressure and Regional Cerebral Blood Flow in Rats. Journal of Sasang Constitution and Immune Medicine. 2000; 12(1) 216-227.
Park Jae-hyung, kim kyung yo. Effect of Taeumin Chungsimyoinjatang Extract on Blood Pressure and Regional Cerebral Blood Flow in Rats. 2000; 12(1), 216-227.
Park Jae-hyung and kim kyung yo. "Effect of Taeumin Chungsimyoinjatang Extract on Blood Pressure and Regional Cerebral Blood Flow in Rats" Journal of Sasang Constitution and Immune Medicine 12, no.1 (2000) : 216-227.
