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@article{ART001142941},
author={윤미숙 and Minho Moon and Joowon Jeong and 김정혜 and 안희경 and 허영범 and 박 찬},
title={The Effects of Repeated Restraint Stress on the Synaptic Plasticity in the Inner Molecular Layerof Mouse Dentate Gyrus},
journal={Anatomy & Biological Anthropology},
issn={2671-5651},
year={2006},
volume={19},
number={4},
pages={325-337},
doi={10.11637/aba.2006.19.4.325}

TY - JOUR
AU - 윤미숙
AU - Minho Moon
AU - Joowon Jeong
AU - 김정혜
AU - 안희경
AU - 허영범
AU - 박 찬
TI - The Effects of Repeated Restraint Stress on the Synaptic Plasticity in the Inner Molecular Layerof Mouse Dentate Gyrus
JO - Anatomy & Biological Anthropology
PY - 2006
VL - 19
IS - 4
PB - 대한체질인류학회
SP - 325
EP - 337
SN - 2671-5651
AB - Stress induces degeneration of brain structures and functions. Particularly, hippocampus is sensitive to stressful stimulations. In the present study, the change of synaptic related molecules in the mouse dentate gyrus was examined with immunohistochemistry after restraint stress. We subjected mice to restraint stress for 6 h per day for 4 days. As a result, the number of Ki-67, a marker for proliferation, and doublecortin (DCX), a marker for neurogenesis, immunoreactive cells was decreased in the stress group. On the other hand, the intensity of calbindinD-28k, a marker of pre-existing granule cells, immunoreactivity was increased in the granule cell layer after 4 days restraint stress. As well as, the immunoreactivity of synaptic related molecules, postsynaptic density-95 (PSD-95), growth association protein-43 (GAP-43) and β-NADPH-d reactivity were increased in the inner molecular layer of dentate gyrus after 4 days restraint stress. In conclusion, this study shows that repeated restraint stress suppresses neurogenesis in dentate gyrus and strengthens synaptic plasticity of existing granule cells.
KW - Restraint stress;Dentate gyrus;Inner molecular layer;Post synaptic density-95;Doublecortin;Growth associated protein-43;β-NADPH-d
DO - 10.11637/aba.2006.19.4.325
ER -

윤미숙, Minho Moon, Joowon Jeong, 김정혜, 안희경, 허영범 and 박 찬. (2006). The Effects of Repeated Restraint Stress on the Synaptic Plasticity in the Inner Molecular Layerof Mouse Dentate Gyrus. Anatomy & Biological Anthropology, 19(4), 325-337.

윤미숙, Minho Moon, Joowon Jeong, 김정혜, 안희경, 허영범 and 박 찬. 2006, "The Effects of Repeated Restraint Stress on the Synaptic Plasticity in the Inner Molecular Layerof Mouse Dentate Gyrus", Anatomy & Biological Anthropology, vol.19, no.4 pp.325-337. Available from: doi:10.11637/aba.2006.19.4.325

윤미숙, Minho Moon, Joowon Jeong, 김정혜, 안희경, 허영범, 박 찬 "The Effects of Repeated Restraint Stress on the Synaptic Plasticity in the Inner Molecular Layerof Mouse Dentate Gyrus" Anatomy & Biological Anthropology 19.4 pp.325-337 (2006) : 325.

윤미숙, Minho Moon, Joowon Jeong, 김정혜, 안희경, 허영범, 박 찬. The Effects of Repeated Restraint Stress on the Synaptic Plasticity in the Inner Molecular Layerof Mouse Dentate Gyrus. 2006; 19(4), 325-337. Available from: doi:10.11637/aba.2006.19.4.325

윤미숙, Minho Moon, Joowon Jeong, 김정혜, 안희경, 허영범 and 박 찬. "The Effects of Repeated Restraint Stress on the Synaptic Plasticity in the Inner Molecular Layerof Mouse Dentate Gyrus" Anatomy & Biological Anthropology 19, no.4 (2006) : 325-337.doi: 10.11637/aba.2006.19.4.325

윤미숙; Minho Moon; Joowon Jeong; 김정혜; 안희경; 허영범; 박 찬. The Effects of Repeated Restraint Stress on the Synaptic Plasticity in the Inner Molecular Layerof Mouse Dentate Gyrus. Anatomy & Biological Anthropology, 19(4), 325-337. doi: 10.11637/aba.2006.19.4.325

윤미숙; Minho Moon; Joowon Jeong; 김정혜; 안희경; 허영범; 박 찬. The Effects of Repeated Restraint Stress on the Synaptic Plasticity in the Inner Molecular Layerof Mouse Dentate Gyrus. Anatomy & Biological Anthropology. 2006; 19(4) 325-337. doi: 10.11637/aba.2006.19.4.325

윤미숙, Minho Moon, Joowon Jeong, 김정혜, 안희경, 허영범, 박 찬. The Effects of Repeated Restraint Stress on the Synaptic Plasticity in the Inner Molecular Layerof Mouse Dentate Gyrus. 2006; 19(4), 325-337. Available from: doi:10.11637/aba.2006.19.4.325

윤미숙, Minho Moon, Joowon Jeong, 김정혜, 안희경, 허영범 and 박 찬. "The Effects of Repeated Restraint Stress on the Synaptic Plasticity in the Inner Molecular Layerof Mouse Dentate Gyrus" Anatomy & Biological Anthropology 19, no.4 (2006) : 325-337.doi: 10.11637/aba.2006.19.4.325