@article{ART001142988},
author={오수연 and 박웅채 and 김경래 and 왕준호 and 이재동 and 김순제 and 송우철 and 박승화},
title={The Morphometric Changes of the Enteric Nervous System in the Intestinal Transection- reanastomosis Model},
journal={Anatomy & Biological Anthropology},
issn={2671-5651},
year={2007},
volume={20},
number={1},
pages={21-34},
doi={10.11637/aba.2007.20.1.21}
TY - JOUR
AU - 오수연
AU - 박웅채
AU - 김경래
AU - 왕준호
AU - 이재동
AU - 김순제
AU - 송우철
AU - 박승화
TI - The Morphometric Changes of the Enteric Nervous System in the Intestinal Transection- reanastomosis Model
JO - Anatomy & Biological Anthropology
PY - 2007
VL - 20
IS - 1
PB - 대한체질인류학회
SP - 21
EP - 34
SN - 2671-5651
AB - This study was performed to investigate the morphometric changes of myenteric plexus and type 1 interstitial cells of
Cajal (ICC-I) in regeneration process of small intestine transection.
Sprague Dawley rats (200~250 g) were anesthetized with ether; then the full thickness of ileal wall were semitransected;
and subsequent end-to-end anastomosis were performed by using 6-0 silk suture thread. Sham-operated rats,
which only underwent the laparotomy, were used for control group. Experimental animals were sacrificed at 3 days, 7
days, 15 days, and 30 days after the operation. In each group myenteric plexus and ICC-Is were prepared by histochemical
method (NADH-TR stain for myenteric plexus, ZIO stain for ICC-Is) and cell numbers were counted by
image analyzer (Image plus pro-5.0, Media Cybermedics, USA).
Degeneration of myenteric neurons and ICC-Is occurred simultaneously and it was similar in oral and anal to the site
of transection. Degeneration effects were most prominent at 3 days and 7 days after intestinal transection. In myenteric
plexus, many neurons had degenerated appearances and about 40% of them were lost. Most of ICC-Is had cytoplasmic
vacuoles and 20~37% of the cells were lost. At 15 days after transection, there were no more degeneration in
myenteric neurons (20~25% cell loss) and ICC-Is (20~13% cell loss). At 30 days after transection, numbers of
myenteric neurons were not recovered as that of the control group. However numbers of ICC-Is were as similar as that
of the control group.
In conclusion, we confirmed that degeneration effects of intestinal transection are more severe in myenteric plexus
than in ICC-Is, and recovery of cell loss occurs more slowly in myenteric plexus.
KW - Intestinal transection-reanastomosis;Myenteric plexus;Type 1 interstitial cells of Cajal (ICC-Is);Regeneration;
Morphometry
DO - 10.11637/aba.2007.20.1.21
ER -
오수연, 박웅채, 김경래, 왕준호, 이재동, 김순제, 송우철 and 박승화. (2007). The Morphometric Changes of the Enteric Nervous System in the Intestinal Transection- reanastomosis Model. Anatomy & Biological Anthropology, 20(1), 21-34.
오수연, 박웅채, 김경래, 왕준호, 이재동, 김순제, 송우철 and 박승화. 2007, "The Morphometric Changes of the Enteric Nervous System in the Intestinal Transection- reanastomosis Model", Anatomy & Biological Anthropology, vol.20, no.1 pp.21-34. Available from: doi:10.11637/aba.2007.20.1.21
오수연, 박웅채, 김경래, 왕준호, 이재동, 김순제, 송우철, 박승화 "The Morphometric Changes of the Enteric Nervous System in the Intestinal Transection- reanastomosis Model" Anatomy & Biological Anthropology 20.1 pp.21-34 (2007) : 21.
오수연, 박웅채, 김경래, 왕준호, 이재동, 김순제, 송우철, 박승화. The Morphometric Changes of the Enteric Nervous System in the Intestinal Transection- reanastomosis Model. 2007; 20(1), 21-34. Available from: doi:10.11637/aba.2007.20.1.21
오수연, 박웅채, 김경래, 왕준호, 이재동, 김순제, 송우철 and 박승화. "The Morphometric Changes of the Enteric Nervous System in the Intestinal Transection- reanastomosis Model" Anatomy & Biological Anthropology 20, no.1 (2007) : 21-34.doi: 10.11637/aba.2007.20.1.21
오수연; 박웅채; 김경래; 왕준호; 이재동; 김순제; 송우철; 박승화. The Morphometric Changes of the Enteric Nervous System in the Intestinal Transection- reanastomosis Model. Anatomy & Biological Anthropology, 20(1), 21-34. doi: 10.11637/aba.2007.20.1.21
오수연; 박웅채; 김경래; 왕준호; 이재동; 김순제; 송우철; 박승화. The Morphometric Changes of the Enteric Nervous System in the Intestinal Transection- reanastomosis Model. Anatomy & Biological Anthropology. 2007; 20(1) 21-34. doi: 10.11637/aba.2007.20.1.21
오수연, 박웅채, 김경래, 왕준호, 이재동, 김순제, 송우철, 박승화. The Morphometric Changes of the Enteric Nervous System in the Intestinal Transection- reanastomosis Model. 2007; 20(1), 21-34. Available from: doi:10.11637/aba.2007.20.1.21
오수연, 박웅채, 김경래, 왕준호, 이재동, 김순제, 송우철 and 박승화. "The Morphometric Changes of the Enteric Nervous System in the Intestinal Transection- reanastomosis Model" Anatomy & Biological Anthropology 20, no.1 (2007) : 21-34.doi: 10.11637/aba.2007.20.1.21
